OPT Clinical Manager Jobs
Clinical Manager roles on OPT typically fall under healthcare administration or public health, both solid specialty occupation categories for H-1B visa sponsorship. Most positions require a relevant master's or bachelor's degree. STEM OPT extension eligibility depends on your specific program classification, so confirm your CIP code with your DSO early.
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Get Access To All JobsWork Schedule
Standard (Mon-Fri)
Environmental Conditions
Office
Job Description
As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.
Job Description:
The Clinical Research Manager III independently leads complex, high-visibility clinical research projects, ensuring strong scientific quality, operational performance, financial oversight, and client satisfaction. This role manages cross-functional teams, builds trusted client relationships, mentors junior colleagues, and promotes consistent, efficient project delivery across the organization.
Key Responsibilities
- Lead complex projects from initiation through completion, ensuring deliverables meet quality, timeline, budget, and client expectations.
- Develop strong client partnerships, anticipate needs, identify risks and opportunities, and provide proactive project guidance.
- Manage project finances, including forecasting, budget oversight, variance analysis, and performance tracking.
- Coordinate collaboration across Clinical Epidemiology, Biostatistics, Pharmacovigilance, and other internal teams.
- Review project deliverables for scientific accuracy, clarity, consistency, and alignment with client and organizational standards.
- Supervise, coach, and mentor Research Coordinators, Clinical Research Managers, and other team members.
- Identify and implement process improvements that increase efficiency, visibility, accountability, and quality.
- Administer policies and procedures that affect team operations and workflow.
Qualifications
- Bachelor’s degree or an equivalent combination of education, training, and relevant experience.
- Up to five years of related experience, including at least one year of leadership responsibility.
- Advanced knowledge of project management methods and tools.
- Demonstrated ability to independently manage multiple complex or multi-registry projects.
- Strong strategic thinking, problem-solving, and analytical skills.
- Excellent client-facing, communication, and cross-functional collaboration capabilities.
- Experience managing project budgets, forecasts, and financial performance.
- Proven ability to lead, influence, coach, and develop multidisciplinary teams.
- Proficiency in Microsoft Office and familiarity with project management and financial tracking systems.
Why Join Us?
When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You’ll work in an environment where collaboration and development are part of the everyday experience—and where your contributions truly make a difference.
Compensation and Benefits
The salary range estimated for this position based in Massachusetts is $105,000.00–$115,000.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
- A choice of national medical and dental plans, and a national vision plan, including health incentive programs
- Employee assistance and family support programs, including commuter benefits and tuition reimbursement
- At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
- Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
- Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
Work Schedule
Standard (Mon-Fri)
Environmental Conditions
Office
Job Description
As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.
Job Description:
The Clinical Research Manager III independently leads complex, high-visibility clinical research projects, ensuring strong scientific quality, operational performance, financial oversight, and client satisfaction. This role manages cross-functional teams, builds trusted client relationships, mentors junior colleagues, and promotes consistent, efficient project delivery across the organization.
Key Responsibilities
- Lead complex projects from initiation through completion, ensuring deliverables meet quality, timeline, budget, and client expectations.
- Develop strong client partnerships, anticipate needs, identify risks and opportunities, and provide proactive project guidance.
- Manage project finances, including forecasting, budget oversight, variance analysis, and performance tracking.
- Coordinate collaboration across Clinical Epidemiology, Biostatistics, Pharmacovigilance, and other internal teams.
- Review project deliverables for scientific accuracy, clarity, consistency, and alignment with client and organizational standards.
- Supervise, coach, and mentor Research Coordinators, Clinical Research Managers, and other team members.
- Identify and implement process improvements that increase efficiency, visibility, accountability, and quality.
- Administer policies and procedures that affect team operations and workflow.
Qualifications
- Bachelor’s degree or an equivalent combination of education, training, and relevant experience.
- Up to five years of related experience, including at least one year of leadership responsibility.
- Advanced knowledge of project management methods and tools.
- Demonstrated ability to independently manage multiple complex or multi-registry projects.
- Strong strategic thinking, problem-solving, and analytical skills.
- Excellent client-facing, communication, and cross-functional collaboration capabilities.
- Experience managing project budgets, forecasts, and financial performance.
- Proven ability to lead, influence, coach, and develop multidisciplinary teams.
- Proficiency in Microsoft Office and familiarity with project management and financial tracking systems.
Why Join Us?
When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You’ll work in an environment where collaboration and development are part of the everyday experience—and where your contributions truly make a difference.
Compensation and Benefits
The salary range estimated for this position based in Massachusetts is $105,000.00–$115,000.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:
- A choice of national medical and dental plans, and a national vision plan, including health incentive programs
- Employee assistance and family support programs, including commuter benefits and tuition reimbursement
- At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy
- Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan
- Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount
For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards
See all 775+ OPT Clinical Manager Jobs
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Get Access To All JobsTips for Finding OPT Sponsorship as a Clinical Manager
Target healthcare systems with established immigration programs
Large hospital networks and integrated health systems like Kaiser, HCA, and academic medical centers regularly sponsor H-1B visas. They have dedicated HR infrastructure for immigration paperwork, making them far more likely to follow through than smaller clinics.
Frame your degree field precisely in applications
Clinical Manager roles qualify as specialty occupations when the job requires a specific degree in healthcare administration, public health, or nursing. Confirm your resume and cover letter explicitly connect your degree field to the role's clinical oversight responsibilities.
Clarify your OPT end date before the first interview
Hiring timelines for management roles often run 6 to 10 weeks. Know your exact OPT expiration and cap-gap eligibility so you can reassure employers that your work authorization covers the onboarding window without any gap.
Prioritize roles with direct patient care oversight components
Clinical Manager positions with explicit clinical supervision responsibilities are easier to classify as specialty occupations under USCIS standards. Roles blended heavily with general operations management carry more ambiguity and can complicate future H-1B petitions.
Ask about sponsorship timing in the second interview, not the first
Raising H-1B sponsorship in an initial screening can stall your candidacy before employers assess your fit. Wait until there is clear mutual interest, then frame it as a logistics question rather than a demand requiring immediate commitment.
Check whether STEM OPT applies to your specific degree program
Not all healthcare administration or public health degrees carry a STEM CIP code. If yours does, you gain 24 additional months of work authorization. Verify with your DSO before interviewing so you can accurately communicate your authorization timeline to employers.
Clinical Manager OPT: Frequently Asked Questions
Can I work as a Clinical Manager on OPT?
Yes, Clinical Manager roles generally qualify for OPT work authorization as long as the position is directly related to your degree field. A degree in healthcare administration, public health, nursing, or a related clinical discipline typically satisfies that requirement. Confirm the connection between your specific program and the job description with your DSO before accepting an offer.
Do Clinical Manager jobs typically come with H-1B sponsorship?
Sponsorship availability varies significantly by employer size and type. Large hospital networks, academic medical centers, and multi-site healthcare organizations are the most consistent sponsors because they have the legal and HR infrastructure to manage petitions. Smaller outpatient clinics and private practices rarely sponsor. Migrate Mate filters job listings by sponsorship willingness, which helps you focus your search on employers who have sponsored before.
Is a Clinical Manager role considered a specialty occupation for H-1B purposes?
It can be, but the classification depends on how the role is defined. If the job description requires a specific bachelor's degree or higher in a clinical or health administration field, it meets the specialty occupation threshold. Roles where the employer accepts any business or management degree regardless of field are harder to classify. The more clinical the oversight responsibilities, the stronger the specialty occupation argument.
Am I eligible for the STEM OPT extension as a Clinical Manager?
STEM OPT eligibility depends on your degree's CIP code, not the job title. Some health informatics, biomedical sciences, and health services research programs carry qualifying STEM codes. Standard healthcare administration and public health programs often do not. Check your program's CIP code with your DSO as early as possible, since this 24-month extension significantly changes what you can tell employers about your authorization window.
What should I tell a hiring manager who asks about my work authorization timeline?
Be direct and specific. State your OPT expiration date, whether you qualify for a STEM extension, and that H-1B sponsorship through the April lottery would be needed to continue employment beyond that window. Avoid vague answers like 'I have authorization for now.' Employers making management-level hires need to plan 12 to 18 months ahead, and clarity on your timeline builds confidence rather than concern.