Physician Assistant Jobs in St. Louis, MO

Physician Assistant jobs in St. Louis are concentrated across hospital systems and specialty clinics in the Central West End, Clayton, and South County, with strong demand in primary care, orthopedics, and emergency medicine. Employers hiring right now include Washington University in St. Louis, Mercy, and BJC HealthCare. See the openings below and apply to the ones that match your experience.

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Overview

Open roles45
Top employerWashington University in St. Louis
Work type100% On-site
Top credentialBLS Certification
Companies hiring15

Showing 5 of 45+ Physician Assistant jobs

fast track urgent care
Urgent Care Provider — MD / DO / NP / PA / AP (Assistant Physician)
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fast track urgent care
Added 1d ago
Urgent Care Provider — MD / DO / NP / PA / AP (Assistant Physician)
fast track urgent care
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
PALS Certification
51-200

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Esse Health
Medical Assistant/CNA/PCT - Doctor's Office - Lab/Phlebotomy - South County/Tesson Ferry
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Esse Health
Added 2d ago
Medical Assistant/CNA/PCT - Doctor's Office - Lab/Phlebotomy - South County/Tesson Ferry
Esse Health
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification

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BJC HealthCare
Nurse Practitioner or Physician Assistant - GI Clinic at Christian Hospital in Florissant
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BJC HealthCare
Added 2d ago
Nurse Practitioner or Physician Assistant - GI Clinic at Christian Hospital in Florissant
BJC HealthCare
St. Louis, Missouri
Healthcare Administration
Patient Services & Wellbeing
Physicians
$110k.2 - $168k.59/yr
Doctoral degree
10,000+

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Altea Healthcare
Nurse Practitioner or Certified Physician Assistant***Weekend***
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Altea Healthcare
Added 1w ago
Nurse Practitioner or Certified Physician Assistant***Weekend***
Altea Healthcare
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
$420 - $520/hr
On-Site
201-500

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Esse Health
Nurse Practitioner or Physician Assistant - Richmond Heights/Clayton - Part Time!
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Esse Health
Added 2w ago
Nurse Practitioner or Physician Assistant - Richmond Heights/Clayton - Part Time!
Esse Health
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Master's degree in nursing

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See All 45 Physician Assistant Jobs in St. Louis

Find roles in St. Louis that match your experience and apply in just a few clicks.

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Physician Assistant Job Market in St. Louis

Who's Hiring

  • Washington University in St. Louis
    Washington University in St. Louis17
  • Mercy
    Mercy10
  • BJC HealthCare
    BJC HealthCare4
  • AP Health
    AP Health2
  • Esse Health
    Esse Health2

Top Industries Hiring

  • Education
  • Healthcare & Medical Services

Physician Assistant Jobs in St. Louis: Frequently Asked Questions

How do I get a physician assistant job in St. Louis?

Target St. Louis's large academic medical systems, regional health networks, and specialty practices in the Central West End and Clayton, which consistently post the most openings. Candidates with urgent care, orthopedics, or emergency medicine experience have an edge here given how those practices are distributed across the metro. Building connections through clinical rotations at St. Louis's teaching hospitals also opens doors that cold applications often don't.

Which companies hire physician assistants in St. Louis?

Employers hiring physician assistants in St. Louis right now include Washington University in St. Louis, Mercy, and BJC HealthCare, based on current listings on Migrate Mate as of July 2026. The local market is anchored by large academic medical centers, multispecialty clinic groups, and community health organizations spread across the city and inner suburbs.

Are there remote physician assistant jobs in St. Louis?

Yes, but with clear limits, since most physician assistant work is hands-on and requires in-person patient contact. About 0% of physician assistant openings tied to St. Louis are remote or hybrid as of July 2026, and those tend to cluster in telehealth triage, utilization review, and care management roles rather than clinical practice.

How can I get a physician assistant job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is through community health centers, urgent care networks, and federally qualified health centers in underserved neighborhoods, which regularly hire new graduates. Entry-level roles in hospital float pools and outpatient primary care clinics also give new PAs broad exposure quickly. Completing rotations locally at a St. Louis program and staying visible in those networks gives candidates a meaningful head start.

Which industries hire the most physician assistants in St. Louis?

The sectors hiring the most physician assistants in St. Louis are Education and Healthcare & Medical Services, based on current listings on Migrate Mate as of July 2026. St. Louis's role as a regional medical hub, anchored by its major academic and community health institutions, drives consistent demand for PAs across both inpatient and outpatient settings.

See All 45 Physician Assistant Jobs in St. Louis

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