Physician Assistant Jobs in Missouri
Physician assistant jobs in Missouri are concentrated in Kansas City, St. Louis, and Springfield, where major health systems like BJC HealthCare, Children's Mercy, and SSM Health maintain steady hiring pipelines for PAs at every career stage. Demand is strongest in primary care, emergency medicine, and orthopedics, with hospital-employed and multispecialty group roles making up the bulk of active openings. The market draws both new graduates and experienced clinicians, with rural and underserved areas across the state increasingly competitive as well. Scan the live roles below and apply to whichever ones fit.
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Schedule:
- Part-time opportunity, two to three days per week.
- Flexible scheduling, with specific days and hours discussed during the interview process.
- Potential for full-time employment.
Position Overview:
Responsibilities:
- Evaluate patients with orthopedic and chronic pain conditions.
- Develop individualized treatment plans and educate patients on their care.
- Perform joint, trigger point, tendon, sacroiliac, PRP, and peripheral nerve block injections within your scope of practice.
- Perform ultrasound- and C-arm-guided procedures.
- Review diagnostic imaging and use findings to guide treatment.
- Coordinate care with Physical Therapy, Chiropractic, and medical providers.
- Monitor patient progress and adjust care plans as appropriate.
- Lead and support Medical Assistant staff.
- Maintain accurate clinical documentation and follow established protocols.
Minimum Qualifications:
- Graduate of an accredited Physician Assistant program.
- Active Physician Assistant licenses in both Missouri and Kansas.
- Strong clinical reasoning, communication, and leadership skills.
- Ability to work effectively in a fast-paced, multidisciplinary environment.
- Willingness to learn new procedures and follow established clinical protocols.
Preferred qualifications:
- Orthopedic or pain-management experience.
- Experience performing injections.
- Workers’ compensation experience.
- Procedure-specific training is available for candidates whose skills and experience align with the role.
Compensation & Benefits:
- Part-time compensation: $40–$45 per hour.
- Potential full-time compensation: $85,000–$110,000 annually.
- Flexible scheduling.
- 401(k).
- Dental insurance.
- Tuition reimbursement.
Additional benefits may include health insurance, vision insurance, life insurance, and paid time off. Eligibility and benefit details will be discussed based on employment status and final offer terms.
About the Area:
Please include your availability for two to three days per week and whether you’re interested in future full-time opportunities when applying.
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Find Physician Assistant JobsPhysician Assistant Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Physician Assistant Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- Mercy17
- GoHealth Urgent Care4
- CoxHealth3
- Esse Health3
- Golden Valley Memorial Healthcare3
Top Industries Hiring
- Education
- Healthcare & Medical Services
What Missouri Employers Look For
The qualifications that appear most often in physician assistant jobs across Missouri.
- Active Missouri physician assistant license issued by the Missouri State Board of Registration for the Healing Arts
- Graduation from an ARC-PA accredited physician assistant program
- Current NCCPA certification or eligibility to sit for the PANCE
- Current BLS certification required, with ACLS preferred for acute care or hospital settings
- Experience in a relevant specialty such as primary care, emergency medicine, or orthopedics
- Strong electronic health record proficiency, with Epic experience commonly preferred by Missouri health systems
Physician Assistant Jobs in Missouri: Frequently Asked Questions
How do you become a physician assistant in Missouri?
To become a physician assistant in Missouri, you must complete a master's-level program accredited by the ARC-PA, pass the PANCE administered by the NCCPA, and then apply for licensure through the Missouri State Board of Registration for the Healing Arts. Missouri requires a licensed supervising physician on file as part of the collaborative practice arrangement. Once licensed, you may practice in any approved setting, including hospitals, outpatient clinics, and rural health centers.
How much do physician assistants make in Missouri?
Physician assistants in Missouri earn a median of about $135,130 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $82,690 for the lowest 10% to over $169,650 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire physician assistants in Missouri?
Companies currently hiring physician assistants in Missouri include Mercy, GoHealth Urgent Care, and CoxHealth, per current listings on Migrate Mate as of October 2026. Missouri's large integrated health systems and academic medical centers tend to post the most consistent volume, with multispecialty group practices and federally qualified health centers also representing a meaningful share of openings.
Which Missouri cities have the most physician assistant jobs?
St. Louis, Kansas City, and Springfield have the most physician assistant openings in Missouri. Kansas City and St. Louis drive the highest volume because of their large academic medical centers and integrated hospital networks, while Springfield's growing regional health sector, anchored by CoxHealth and Mercy, keeps it consistently active for PA hiring as well.
Are there remote physician assistant jobs in Missouri?
Yes, but they're rare. Physician assistant work is inherently hands-on and patient-facing, which limits how much of the role can be performed remotely. About 30% of physician assistant openings tied to Missouri are remote or hybrid as of October 2026, and those positions tend to concentrate in telehealth triage, utilization review, or chronic disease management roles rather than traditional clinical practice.
How can I get hired as a physician assistant in Missouri with little or no experience?
The most realistic entry path is applying directly to new-graduate or postgraduate residency programs, several of which are offered by Missouri-based systems including BJC HealthCare and Mercy. These structured programs are designed for candidates coming straight out of accredited PA programs. Beyond residency, new graduates often enter through urgent care, rural health clinics, and federally qualified health centers, which tend to be more open to onboarding early-career PAs. Having your Missouri license and NCCPA certification in hand before you apply gives you a clear advantage over candidates still awaiting results.
Where can I find and apply to physician assistant jobs in Missouri?
You can find and apply to physician assistant jobs in Missouri on Migrate Mate, which lists current Missouri openings across health systems, group practices, and specialty clinics. Search the listings to find roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.
See All 65 Physician Assistant Jobs in Missouri
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