QA Lead Jobs in Missouri

QA Lead jobs in Missouri are open across O'Fallon, Bridgeton, and Clayton and other Missouri metros, with employers like Mastercard, Centene, and HDR hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles7+
Top employerMastercard
Top cityO'Fallon, MO
Cities hiring4
Work type86% On-site
Top industryTechnology

Showing 5 of 7+ QA Lead jobs

Centene
Lead Data Engineers
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Centene
Added 1w ago
Lead Data Engineers
Centene
Clayton, Missouri
Data Science & Analytics
Data Engineering
Quality Assurance & Testing (QA Testing)
Data Science
$146k - $191k/yr
Remote (US)
Bachelor's
10,000+

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Hunter Engineering Company
Lead Hardware Test Engineer
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Hunter Engineering Company
Added 1w ago
Lead Hardware Test Engineer
Hunter Engineering Company
Bridgeton, Missouri
Specialized Engineering
Mechanical Engineering
Quality Assurance & Testing (QA Testing)
Engineering (Non-Software)
On-Site
Bachelor's
1,001-5,000

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Mastercard
Lead Software Engineer
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Mastercard
Added 2w ago
Lead Software Engineer
Mastercard
O'Fallon, Missouri
Software Engineering
Technical Product & Program Management
Quality Assurance & Testing (QA Testing)
Backend Engineering
Technical Program Management
$140k - $231k/yr
On-Site
Bachelor's
10,000+

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Mastercard
Lead Site Reliability Engineer
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Mastercard
Added 1mo ago
Lead Site Reliability Engineer
Mastercard
O'Fallon, Missouri
Cloud & DevOps
Technical Product & Program Management
Quality Assurance & Testing (QA Testing)
DevOps
Cloud Engineering
Technical Program Management
$122k - $207k/yr
On-Site
Bachelor's
10,000+

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Mastercard
Lead Site Reliability Engineer
We won't show you this job again
Mastercard
Added 3mo ago
Lead Site Reliability Engineer
Mastercard
O'Fallon, Missouri
Cloud & DevOps
Technical Product & Program Management
Quality Assurance & Testing (QA Testing)
DevOps
Cloud Engineering
Technical Program Management
Automation QA
$122k - $207k/yr
On-Site
Bachelor's
10,000+

Have you applied for this role?

See All 7 QA Lead Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

Find QA Lead Jobs

QA Lead Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

O'Fallon
4 jobs
Bridgeton
1 jobs
Clayton
1 jobs
Kansas City
1 jobs

QA Lead Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • Mastercard
    Mastercard4
  • Centene
    Centene1
  • HDR
    HDR1
  • Hunter Engineering Company
    Hunter Engineering Company1

Top Industries Hiring

  • Technology & Software2
  • Automotive1
  • Banking & Financial Services1
  • Fintech1
  • Insurance1

What Missouri Employers Look For

The qualifications that appear most often in QA lead jobs across Missouri.

  • 3 to 7 years of software QA experience with at least one year in a lead or senior role
  • Hands-on experience with automation frameworks such as Selenium, Cypress, or Playwright
  • Proficiency in test management tools including Jira, TestRail, or Zephyr
  • Experience writing and reviewing test plans, test cases, and defect reports
  • Familiarity with CI/CD pipelines and integrating automated tests into build workflows
  • Bachelor's degree in computer science, information systems, or a related field preferred

QA Lead Jobs in Missouri: Frequently Asked Questions

How many QA lead jobs are there in Missouri?

There are 7+ QA lead openings in Missouri on Migrate Mate as of June 2026, with the most roles in O'Fallon, Bridgeton, and Clayton. New positions post regularly as employers across Missouri hire.

Which Missouri cities have the most QA lead jobs?

O'Fallon, Bridgeton, and Clayton have the most QA lead openings in Missouri right now, with additional roles spread across smaller metros statewide.

Which companies hire QA leads in Missouri?

Employers hiring QA leads in Missouri include Mastercard, Centene, and HDR, based on current listings on Migrate Mate as of June 2026.

Are there remote QA lead jobs in Missouri?

Yes. About 14% of QA lead openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.

How do I apply for QA lead jobs in Missouri?

You can apply to QA lead jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.

See All 7 QA Lead Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

Find QA Lead Jobs