Quality Assurance Manager Jobs in Massachusetts
Quality Assurance Manager jobs in Massachusetts are in strong demand, concentrated in the state's life sciences, medical device, defense, and advanced manufacturing sectors, with openings from entry-level QA supervisors through senior quality directors. The largest hiring activity is in the Greater Boston, Worcester, and Lowell corridors, where employers such as Raytheon Technologies, Thermo Fisher Scientific, and Boston Scientific maintain major operations. The most in-demand specialties are FDA regulatory compliance, ISO 13485 quality systems, and software QA for medtech and biopharma. Find a role that fits below and apply directly.
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Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
Headquartered in Boston, Massachusetts, Centessa was recognized as a Great Place to Work® in 2026.
Description of Role
The Associate Director, Clinical Quality Assurance (CQA) will oversee GCP-focused quality assurance for Centessa-sponsored clinical trials (Early to Late Phase), ensuring compliance with global regulations, ICH guidelines, Centessa SOPs, and industry standards. This role leads daily clinical quality operations, maintains effective quality programs and documentation, and ensures GCP compliance and inspection readiness across all regulatory requirements.
Key Responsibilities
- Lead and maintain GCP QA programs, policies, and procedures.
- Serve as primary GCP QA expert and point of contact.
- Ensure clinical programs comply with global health authority regulations and ICH guidelines.
- Provide QA oversight for protocols, ICFs, CSRs, and other trial documents.
- Monitor evolving GCP regulations and communicate impact to stakeholders.
- Develop and execute global GCP audit strategies and annual plans.
- Conduct and manage audits of investigator sites, CROs, suppliers, systems, and documents.
- Prepare audit reports, evaluate CAPAs, and ensure effective follow-up.
- Lead inspection readiness activities and support regulatory inspections (e.g., FDA, EMA, MHRA).
- Partner with cross-functional teams to ensure compliance.
- Represent CQA on study teams and contribute to protocol design and risk management.
- Collaborate on procedures, forms, and templates related to clinical quality.
- Identify compliance risks and implement mitigation strategies.
- Investigate quality issues, perform root cause analyses, and drive CAPA resolution.
- Prepare and present KPIs, metrics, and audit status updates to leadership.
- Develop and maintain GCP-related SOPs, training materials, and quality metrics.
- Lead process improvement initiatives across QA and broader organization.
- Provide mentorship and leadership to QA staff; may include direct management
Qualifications
- BS or higher in Life Sciences, Chemistry, Pharmacy, or related field.
- 8–10 years of experience in pharmaceutical quality roles.
- Experience with document control software (e.g., ZenQMS, Veeva Vault, MasterControl) required.
Compensation
The annual base salary range for this position is $140,000.00 to $180,000.00. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, job knowledge and location.
In addition to base pay, this role is eligible for a discretionary annual bonus. The Company also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program.
Work Location
The Associate Director, Clinical Quality Assurance role is based in the US, with occasional travel.
POSITION: Full-Time, Exempt
EEOC Statement: Centessa Pharmaceuticals, a wholly owned subdisary of Eli Lilly and Company believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. We will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.
Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, is a clinical-stage company developing orexin receptor 2 (OX2R) agonists as a new class of medicines for the treatment of narcolepsy and potentially other sleep-wake disorders. Centessa’s lead investigational candidate – cleminorexton (formerly ORX750) – is being developed for narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia. Centessa's OX2R agonist portfolio includes additional clinical and preclinical-stage assets with potential utility across a broader range of neurological, neurodegenerative, and neuropsychiatric conditions.
Headquartered in Boston, Massachusetts, Centessa was recognized as a Great Place to Work® in 2026.
Description of Role
The Associate Director, Clinical Quality Assurance (CQA) will oversee GCP-focused quality assurance for Centessa-sponsored clinical trials (Early to Late Phase), ensuring compliance with global regulations, ICH guidelines, Centessa SOPs, and industry standards. This role leads daily clinical quality operations, maintains effective quality programs and documentation, and ensures GCP compliance and inspection readiness across all regulatory requirements.
Key Responsibilities
- Lead and maintain GCP QA programs, policies, and procedures.
- Serve as primary GCP QA expert and point of contact.
- Ensure clinical programs comply with global health authority regulations and ICH guidelines.
- Provide QA oversight for protocols, ICFs, CSRs, and other trial documents.
- Monitor evolving GCP regulations and communicate impact to stakeholders.
- Develop and execute global GCP audit strategies and annual plans.
- Conduct and manage audits of investigator sites, CROs, suppliers, systems, and documents.
- Prepare audit reports, evaluate CAPAs, and ensure effective follow-up.
- Lead inspection readiness activities and support regulatory inspections (e.g., FDA, EMA, MHRA).
- Partner with cross-functional teams to ensure compliance.
- Represent CQA on study teams and contribute to protocol design and risk management.
- Collaborate on procedures, forms, and templates related to clinical quality.
- Identify compliance risks and implement mitigation strategies.
- Investigate quality issues, perform root cause analyses, and drive CAPA resolution.
- Prepare and present KPIs, metrics, and audit status updates to leadership.
- Develop and maintain GCP-related SOPs, training materials, and quality metrics.
- Lead process improvement initiatives across QA and broader organization.
- Provide mentorship and leadership to QA staff; may include direct management
Qualifications
- BS or higher in Life Sciences, Chemistry, Pharmacy, or related field.
- 8–10 years of experience in pharmaceutical quality roles.
- Experience with document control software (e.g., ZenQMS, Veeva Vault, MasterControl) required.
Compensation
The annual base salary range for this position is $140,000.00 to $180,000.00. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, job knowledge and location.
In addition to base pay, this role is eligible for a discretionary annual bonus. The Company also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program.
Work Location
The Associate Director, Clinical Quality Assurance role is based in the US, with occasional travel.
POSITION: Full-Time, Exempt
EEOC Statement: Centessa Pharmaceuticals, a wholly owned subdisary of Eli Lilly and Company believes in a diverse environment and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion, or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. We will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Please note: We will not assign referral rights for any unsolicited resumes from recruitment agencies.
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Find JobsQuality Assurance Manager Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Quality Assurance Manager Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Electronics & Hardware
- Biotechnology & Pharmaceuticals
- Medical Devices
- Technology & Software
- Distribution & Wholesale
What Massachusetts Employers Look For
The qualifications that appear most often in quality assurance manager jobs across Massachusetts.
- Bachelor's degree in engineering, life sciences, or a related technical field required
- Five or more years of quality assurance experience in a regulated manufacturing environment
- Hands-on expertise with ISO 9001, ISO 13485, or FDA 21 CFR Part 820 quality systems
- Demonstrated experience leading internal audits, CAPA processes, and nonconformance investigations
- Proficiency with statistical tools such as SPC, Minitab, or Six Sigma methodologies
- Strong written communication skills for producing technical documentation and regulatory submissions
Quality Assurance Manager Jobs in Massachusetts: Frequently Asked Questions
How do you become a quality assurance manager in Massachusetts?
Most quality assurance managers in Massachusetts build their path through a bachelor's degree in engineering, biology, chemistry, or a related field, followed by progressive QA roles in regulated industries such as medical devices, biopharma, or defense. Massachusetts does not require a state-issued license for the role, but employers in regulated sectors heavily favor candidates with ASQ Certified Quality Manager credentials or equivalent certifications. Experience with FDA quality systems and ISO standards is expected before moving into management.
How much do quality assurance managers make in Massachusetts?
Quality assurance managers in Massachusetts earn a median of about $148,050 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $99,920 for the lowest 10% to over $227,080 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire quality assurance managers in Massachusetts?
Employers hiring quality assurance managers in Massachusetts right now include Teleflex, Integrated Pharmacy Solutions, and Replimune, based on current listings on Migrate Mate as of September 2026. Massachusetts's deep concentration of medical device, biopharma, and defense contractors makes it one of the most consistent states for quality management hiring across the country.
Which Massachusetts cities have the most quality assurance manager jobs?
Boston, Waltham, and Massachusetts have the most quality assurance manager openings in Massachusetts. Greater Boston drives the largest share, anchored by its dense cluster of biopharma and medical device headquarters, while Worcester and Lowell reflect the strength of advanced manufacturing and defense operations that have long been rooted in the Merrimack Valley and Central Massachusetts.
Are there remote quality assurance manager jobs in Massachusetts?
Yes, but they're less common than in purely desk-based fields, because quality assurance managers in Massachusetts frequently need to be on the production floor, in the lab, or at an audit site. About 54% of quality assurance manager openings tied to Massachusetts are remote or hybrid as of September 2026. The parts of the role most suited to remote work are documentation review, supplier audits conducted virtually, and regulatory submission writing.
How can I get hired as a quality assurance manager in Massachusetts with little or no experience?
The most realistic entry path is starting as a quality assurance technician or quality control associate at a Massachusetts medical device or biopharma company, then working toward a supervisory role. Large employers such as Thermo Fisher Scientific and Boston Scientific regularly bring in new graduates for QA associate and documentation specialist roles that feed the management pipeline. Earning an ASQ Certified Quality Improvement Associate credential early, and gaining hands-on exposure to CAPA and batch record review, meaningfully strengthens a candidate's profile before pursuing a manager title.
Where can I find and apply to quality assurance manager jobs in Massachusetts?
You can find and apply to quality assurance manager jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across life sciences, manufacturing, defense, and technology. Find roles that fit your background and apply directly to the employers posting them.
See All 105+ Quality Assurance Manager Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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