Regional Manager Jobs in Denver, CO
Regional Manager jobs in Denver are concentrated in the LoDo, Cherry Creek, and Stapleton corridors, with strong demand across retail, healthcare, and financial services. Employers actively hiring right now include Mission Rock Residential, KETTLER, and NOV. Scan the live roles below and apply to whichever ones fit.
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A Rare Opportunity to Shape the Future of Genomics
Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
We are looking for a Regional Manager - Prenatal, Denver (CO) with 4+ years of direct sales management experience out of Women's Health, Prenatal Diagnostics, or Reproductive Health within Denver. You will build, develop, and lead a high impact team of sales reps who will bring the first and only single-gene NIPT supported carrier and aneuploidy screen to OBGYN clinics, MFMs, and private OBGYN practices throughout the Denver area. You will deliver clinical information to both external clients and internal teams. You will have significant influence over how the test is communicated to physicians and patients, and contribute to how the test evolves to better serve market needs. The Regional Manager - Prenatal is a remote position and reports to the Area Director.
Responsibilities:
- Develop a comprehensive, data-driven sales strategy and business plan to build and grow market development throughout the Denver region
- Build and lead a team of talented, high performing sales reps in the execution of sales strategies and optimization of opportunities to increase profitability and market share
- Recruit, Hire, Train, Manage, and Develop representatives
- Develop and enhance customized pitches to individual OBGYNs, MFMs, and prenatal Genetic Counselors.
- Use data to analyze sales results, identify industry trends, and stay abreast of competition to increase sales volume and drive success within territory
- Minimum 4+ years of field sales management experience leading a team of sales reps at a molecular diagnostics/genetics company required, specifically out of Women's Health, Prenatal, and/or Reproductive Health selling directly to OBGYNs, MFMs, GCs throughout the Denver, with an existing portfolio of convertible client relationships
- Strong experience hiring, developing, coaching, and motivating a team of sales reps to exceed ambitious sales goals
- Must have prior experience in lab diagnostics
- Demonstrated successful sales track record (eg. multiple award winning - President's Club, Chairman's Club, Circle of Excellence or equivalent), solid negotiation and closing skills, strong data analysis skills, understanding of buyer/decision maker types, exhibit effective selling, listening, presentation skills, strong focus on pull through, and good follow through skills
- Excellent organizational and communication skills (written and verbal) with demonstrated ability to effectively present to both internal and external customers.
- Effective time management skills required with a demonstrated ability to assess and prioritize opportunities required
- Exceptionally bright, flexible, self-motivated and results oriented with strong interpersonal and analytical skills and the ability to think strategically as well as execute tactically
- Must act with a sense of urgency, with a focus on closing business
- Ability to assess the needs of OBGYNs & MFMs and their office staff with a focus on consultative sales, coordination of logistics, and problem solving
- Strong desire to work in a startup environment and build out a new territory and team
Nice-to-Haves:
- Experience in a start-up environment
- Clinical laboratory experience
Benefits And Perks:
- Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousand patients
- Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
- Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
- Supplemental fertility benefits coverage
- Retirement savings program including a 4% Company match
- Increase paid time off with increased tenure
- Latest and greatest hardware (laptop, lab equipment, facilities)
At BillionToOne, we are proud to offer a combination of (1) base pay (2) generous equity options offering, on top of (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave etc.).
For this position, we offer a total compensation of $313,209 per year (at plan), including a base salary range of $205,509 per year. Commission potential is uncapped and can be significant.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
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BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact
Unity Completeâ„¢ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirmâ„¢ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne's Fetal Cell Captureâ„¢ Technology.
Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth
From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition
Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future
Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.
Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com
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Who's Hiring



Top Industries Hiring
- Construction & Real Estate
Regional Manager Jobs in Denver: Frequently Asked Questions
How do I get a regional manager job in Denver?
Focus on Denver's highest-volume hiring sectors: retail chains with Front Range footprints, healthcare networks anchored in the Denver metro, and financial services firms based in the central business district. Candidates who demonstrate multi-unit oversight experience in Colorado's mountain-to-metro markets stand out. Networking through Denver Metro Chamber of Commerce events and targeting employers expanding along the I-25 corridor gives a practical edge over applicants applying from outside the region.
Which companies hire regional managers in Denver?
Companies currently hiring regional managers in Denver include Mission Rock Residential, KETTLER, and NOV, per current listings on Migrate Mate as of November 2026. Denver's mix of national retail brands, regional healthcare systems, and homegrown technology and outdoor-industry companies creates a broad base of employers regularly seeking regional leadership talent.
Are there remote regional manager jobs in Denver?
Yes, though remote availability depends heavily on the role's function: operations and field-management positions are almost always on-site, while analytical, planning, and inside-sales regional roles run remote more often. About 86% of regional manager openings tied to Denver are remote or hybrid as of November 2026, with hybrid schedules most common among Denver's technology and financial services employers.
How can I get a regional manager job in Denver with little or no experience?
The most realistic path in Denver is moving up through assistant or district manager roles at retail and food-service chains that operate multiple Front Range locations, since those employers promote from within and hire entry-level supervisors regularly. Denver's growing healthcare and logistics sectors also use team-lead and shift-supervisor roles as a pipeline into regional oversight. Highlighting measurable results from any multi-site or cross-location responsibility, even in a smaller scope, makes a meaningful difference to Denver hiring managers.
Which industries hire the most regional managers in Denver?
The sectors hiring the most regional managers in Denver are Construction & Real Estate, based on current listings on Migrate Mate as of November 2026. Denver's role as a regional hub for the Mountain West drives outsized demand, as companies use the city as a base for overseeing operations across Colorado, Utah, and neighboring states.
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