Registered Nurse Jobs in St. Louis, MO

Registered Nurse jobs in St. Louis are concentrated across the medical corridor along Forest Park Avenue, the Central West End, and south city hospital campuses, with strong demand in acute care, pediatrics, and critical care. Employers hiring right now include SSM Health, LiveWell Homecare Agency, and BJC HealthCare. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles116+
Top employerSSM Health
Work type100% Remote
Top credentialBLS Certification
Companies hiring9

Showing 5 of 116+ Registered Nurse jobs

SSM Health
Registered Nurse - Clinical - Neurology
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SSM Health
New 23h ago
Registered Nurse - Clinical - Neurology
SSM Health
St. Louis, Missouri
Customer Service
Customer Success
Customer Support
BLS Certification
10,000+

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SSM Health
Registered Nurse - Intensive Care Unit (ICU) - Cardiology
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SSM Health
New 23h ago
Registered Nurse - Intensive Care Unit (ICU) - Cardiology
SSM Health
St. Louis, Missouri
Customer Service
Customer Success
Customer Support
BLS Certification
10,000+

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SSM Health
Registered Nurse - Medical Surgical
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SSM Health
New 23h ago
Registered Nurse - Medical Surgical
SSM Health
St. Louis, Missouri
Customer Service
Customer Success
Customer Support
BLS Certification
10,000+

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SSM Health
Registered Nurse - Intensive Care Unit - Cardiology
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SSM Health
New 23h ago
Registered Nurse - Intensive Care Unit - Cardiology
SSM Health
St. Louis, Missouri
Customer Service
Customer Success
Customer Support
BLS Certification
10,000+

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Vituity
Aesthetic RN - MOOV - St. Louis
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Vituity
Added 1d ago
Aesthetic RN - MOOV - St. Louis
Vituity
St. Louis, Missouri
Caregiving & Elderly Support
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
1,001-5,000

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Registered Nurse Job Market in St. Louis

Who's Hiring

  • SSM Health
    SSM Health51
  • L
    LiveWell Homecare Agency24
  • BJC HealthCare
    BJC HealthCare15
  • Mercy
    Mercy9
  • Suncrest Hospice
    Suncrest Hospice6

Registered Nurse Jobs in St. Louis: Frequently Asked Questions

How do I get a registered nurse job in St. Louis?

Focus your search on St. Louis's dense cluster of large health systems, children's hospitals, and specialty care centers, which do the bulk of local hiring. Acute care, oncology, and critical care units tend to have the most consistent openings. Candidates who have completed clinical rotations at a St. Louis facility or hold a BSN have a clear edge over the field in this market.

Which companies hire registered nurses in St. Louis?

St. Louis registered nurse roles are posted by SSM Health, LiveWell Homecare Agency, and BJC HealthCare and others right now, based on current listings on Migrate Mate as of September 2026. The local market is anchored by major academic medical centers, community hospital networks, and specialty pediatric and rehabilitation facilities that hire across nearly every nursing discipline.

Are there remote registered nurse jobs in St. Louis?

Yes, though remote opportunities are limited for most registered nurse roles because the work is fundamentally hands-on and patient-facing. About 100% of registered nurse openings tied to St. Louis are remote or hybrid as of September 2026, concentrated in care management, utilization review, and telehealth triage positions rather than bedside or procedural roles.

How can I get a registered nurse job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is a new-graduate residency program, which most of the city's large health systems and academic medical centers run on a rolling basis. Community hospitals in south city and north county often have more flexible experience requirements than flagship academic sites. Certifications in BLS and ACLS, combined with local clinical hours, strengthen any application significantly.

See All 116+ Registered Nurse Jobs in St. Louis

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