Registered Nurse Jobs in St. Louis, MO

Registered Nurse jobs in St. Louis are concentrated across the medical corridor along Forest Park Avenue, the Central West End, and south city hospital campuses, with strong demand in acute care, pediatrics, and critical care. Employers hiring right now include SSM Health, Mercy, and BJC HealthCare. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles565+
Top employerSSM Health
Work type82% On-site
Top credentialBLS Certification
Companies hiring70

Showing 5 of 565+ Registered Nurse jobs

BJC HealthCare
Medical ICU (MICU) Registered Nurse - Rotating or Nights
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BJC HealthCare
New 1m ago
Medical ICU (MICU) Registered Nurse - Rotating or Nights
BJC HealthCare
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Nursing Diploma
10,000+

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State of Missouri
RN House Supervisor
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State of Missouri
New 1m ago
RN House Supervisor
State of Missouri
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Managed Registered Nurses (RNs)

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State of Missouri
Registered Nurse (FTC-South)
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State of Missouri
New 1m ago
Registered Nurse (FTC-South)
State of Missouri
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Nursing Diploma

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Mercy
RN - Supervisor, LDRP (Evenings)
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Mercy
New 1m ago
RN - Supervisor, LDRP (Evenings)
Mercy
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
TNCC Certification
10,000+

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Mercy
RN Care Manager II-IPCM (NRN Care Manager I-IPCM-Weekend)
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Mercy
New 1m ago
RN Care Manager II-IPCM (NRN Care Manager I-IPCM-Weekend)
Mercy
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
10,000+

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Registered Nurse Job Market in St. Louis

Who's Hiring

  • SSM Health
    SSM Health131
  • Mercy
    Mercy126
  • BJC HealthCare
    BJC HealthCare70
  • American Traveler
    American Traveler69
  • Washington University in St. Louis
    Washington University in St. Louis33

Top Industries Hiring

  • Healthcare & Medical Services283
  • Education24
  • Technology & Software7
  • Consulting & Professional Services2

Registered Nurse Jobs in St. Louis: Frequently Asked Questions

How do I get a registered nurse job in St. Louis?

Focus your search on St. Louis's dense cluster of large health systems, children's hospitals, and specialty care centers, which do the bulk of local hiring. Acute care, oncology, and critical care units tend to have the most consistent openings. Candidates who have completed clinical rotations at a St. Louis facility or hold a BSN have a clear edge over the field in this market.

Which companies hire registered nurses in St. Louis?

St. Louis registered nurse roles are posted by SSM Health, Mercy, and BJC HealthCare and others right now, based on current listings on Migrate Mate as of July 2026. The local market is anchored by major academic medical centers, community hospital networks, and specialty pediatric and rehabilitation facilities that hire across nearly every nursing discipline.

Are there remote registered nurse jobs in St. Louis?

Yes, though remote opportunities are limited for most registered nurse roles because the work is fundamentally hands-on and patient-facing. About 18% of registered nurse openings tied to St. Louis are remote or hybrid as of July 2026, concentrated in care management, utilization review, and telehealth triage positions rather than bedside or procedural roles.

How can I get a registered nurse job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is a new-graduate residency program, which most of the city's large health systems and academic medical centers run on a rolling basis. Community hospitals in south city and north county often have more flexible experience requirements than flagship academic sites. Certifications in BLS and ACLS, combined with local clinical hours, strengthen any application significantly.

Which industries hire the most registered nurses in St. Louis?

St. Louis registered nurse roles concentrate in Healthcare & Medical Services, Education, and Technology & Software, based on current listings on Migrate Mate as of July 2026. The city's position as a major academic medicine and research hub drives sustained hiring across hospital systems, outpatient specialty clinics, and long-term care networks throughout the metro area.

See All 565+ Registered Nurse Jobs in St. Louis

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