Registered Nurse Jobs in St. Louis, MO

Registered Nurse jobs in St. Louis are concentrated across the medical corridor along Forest Park Avenue, the Central West End, and south city hospital campuses, with strong demand in acute care, pediatrics, and critical care. Employers hiring right now include American Traveler, SSM Health, and Moments Hospice. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles82
Top employerAmerican Traveler
Top credentialBLS Certification
Companies hiring11

Showing 5 of 82+ Registered Nurse jobs

Registered Nurse Hospice On-Call
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New 23h ago
Registered Nurse Hospice On-Call
Friendship Village Senior Living Communities
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
501-1,000

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Travel RN - Emergency Dept - Pediatric ED
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Added 1d ago
Travel RN - Emergency Dept - Pediatric ED
American Traveler
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
TNCC Certification
501-1,000

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Travel RN - Cardiovascular ICU
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Added 1d ago
Travel RN - Cardiovascular ICU
American Traveler
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
TNCC Certification
501-1,000

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Travel RN - Home Health
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Added 1d ago
Travel RN - Home Health
American Traveler
St. Louis, Missouri
Healthcare Administration
Patient Services & Wellbeing
Public Health
BLS Certification
501-1,000

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Travel RN - Rehab - In Patient
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Added 2d ago
Travel RN - Rehab - In Patient
American Traveler
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
501-1,000

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Registered Nurse Job Market in St. Louis

Who's Hiring

  • American Traveler27
  • SSM Health12
  • Moments Hospice8
  • Washington University in St. Louis8
  • Mercy4

Registered Nurse Jobs in St. Louis: Frequently Asked Questions

How do I get a registered nurse job in St. Louis?

Focus your search on St. Louis's dense cluster of large health systems, children's hospitals, and specialty care centers, which do the bulk of local hiring. Acute care, oncology, and critical care units tend to have the most consistent openings. Candidates who have completed clinical rotations at a St. Louis facility or hold a BSN have a clear edge over the field in this market.

Which companies hire registered nurses in St. Louis?

St. Louis registered nurse roles are posted by American Traveler, SSM Health, and Moments Hospice and others right now, based on current listings on Migrate Mate as of November 2026. The local market is anchored by major academic medical centers, community hospital networks, and specialty pediatric and rehabilitation facilities that hire across nearly every nursing discipline.

How can I get a registered nurse job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is a new-graduate residency program, which most of the city's large health systems and academic medical centers run on a rolling basis. Community hospitals in south city and north county often have more flexible experience requirements than flagship academic sites. Certifications in BLS and ACLS, combined with local clinical hours, strengthen any application significantly.

See All 82 Registered Nurse Jobs in St. Louis

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