Remote Director of Safety and Compliance Jobs
Remote director of safety and compliance jobs are open across the U.S. at remote-first firms and distributed teams that need compliance leadership without a fixed office. Employers hiring remotely right now include Humana, Centene, and Block, with strong demand in Technology & Software, Insurance, and Accounting & Auditing. Scan the live roles below and apply to whichever ones fit.
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Who We Are
Power Digital is an AI-Native Growth Firm built at the intersection of world-class talent and proprietary technology. We help leading and emerging brands grow by combining deep vertical expertise, strategic thinking, and enterprise intelligence to drive measurable business outcomes. For more than a decade, we have built our business around one belief: the best technology makes great people better. Our teams of strategists, creatives, analysts, and technologists use Omega, our AI operating system, to surface opportunities faster, investigate what is driving performance, and execute approved work with greater speed and precision. Behind Omega is Iris, our proprietary intelligence layer, built on years of real performance data, strategic frameworks, testing, and learnings from across our client portfolio. AI expands the capacity of our people to think, create, solve harder problems, and make better decisions. Human judgment, creativity, and accountability remain central to how we work. As a people-first firm, we value diversity in backgrounds and experiences. We strongly believe our people and culture are key to our success. We partner closely with our clients as an extension of their teams, working across strategy, execution, and measurement to identify what is truly blocking growth and determine what to do next. Our culture is built on people who are curious, ambitious, accountable, and committed to delivering meaningful results for our clients and for one another. At Power Digital, we believe the future belongs to teams that combine the best talent with the best technology. We are building that future today.
We support 100% remote, in-office, or hybrid work styles for anyone legally eligible to work in the U.S.
A Day In The Life
As a Creative Quality & Compliance Specialist, you’ll play an integral part in the overall quality and regulatory integrity of creative output across the Healthcare division, serving as the quality and compliance checkpoint within the creative production workflow. In this role, you’ll report directly to the Creative department and work alongside Creative Project Managers who own delivery timelines and task trafficking. You will act as the gate through which every piece of creative passes before it reaches client Medical, Legal, and Regulatory (MLR) reviewers and again before it goes live. You'll review ads, landing pages, emails, social content, and video for MLR regulatory compliance, brand and design standards, and copy accuracy. Additionally, you’ll operate hands-on inside Veeva Vault PromoMats—managing claims, annotations, references, and submission packages—while building and refining the quality standards the creative team works against to raise the bar across the healthcare portfolio. While your primary authority is quality and compliance, you’ll also support the creative production workflow by maintaining deliverable trackers, coordinating feedback cycles with client stakeholders, and trafficking tasks between the creative team and client POCs. As the Creative Project Manager and Account PM lead delivery management at scale, you will keep the creative lane organized and moving while ensuring nothing ships that shouldn’t.
Key Responsibilities
- Pre-Submission Compliance QA: Review all creative assets against MLR requirements — claims accuracy, fair balance, ISI placement, reference linking, branded vs. unbranded vs. disease-awareness rules — before they enter client Medical, Legal, and Regulatory review.
- Post-Approval Launch QA: Final quality proof of approved assets — landing pages, ads, emails, creative — before they go live, confirming that approved content was implemented correctly and no errors were introduced in production.
- Veeva Vault PromoMats Operations: Own the hands-on Veeva workflow — annotating assets, entering and linking claims, managing references, tracking submission status, and packaging 2253 filings.
- Brand & Design Standards Enforcement: Review creative output for visual consistency, spec adherence, and style guide compliance across all healthcare client deliverables.
- Copy Quality Review: Review all copy for grammar, tone, messaging accuracy, and alignment with approved claims and client brand voice.
- QA Process Documentation & Refinement: Build, maintain, and continuously improve the quality and compliance standards, checklists, and review processes the creative team follows.
- Creative Workflow Coordination: Support creative production operations alongside the Creative Project Manager and Account PM — maintaining Asana boards and deliverable trackers, communicating timelines and managing feedback cycles with client stakeholders, trafficking tasks between the creative team and client POCs, coordinating with cross-channel PMs on shared deliverables, and organizing client-provided assets within Power Digital’s file structure.
- Employ AI technologies to enhance and optimize business processes.
- Utilize and leverage Power Digital’s Nova ecosystem as it relates to your department.
- Other applicable or related duties as assigned.
Role Requirements
- 4+ years in healthcare or pharmaceutical creative production, agency or in-house, with direct exposure to MLR review workflows
- Demonstrated understanding of FDA OPDP guidance and 21 CFR 202, including fair balance, ISI placement, branded vs. unbranded vs. disease-awareness content rules, and 2253 filing requirements
- Veeva Vault PromoMats experience (annotating, claims management, submission tracking) highly preferred
- Strong eye for brand consistency, design quality, and copy accuracy across digital formats (paid social, display, landing pages, email)
- Process-oriented with the ability to document, maintain, and improve QA standards without external direction
- Comfortable reviewing and providing clear, actionable feedback on creative work from designers, copywriters, and freelancers
- Proficiency with Asana or comparable project management platforms
- Experience working alongside project management teams in a fast-paced agency environment
- Bonus: Veeva PromoMats certification, experience with modular content strategies, or prior work across both pharma-regulated and non-regulated healthcare clients
Key Performance Indicators (KPIs)
- First-pass approval rate: 80%+ of assets cleared by client M/L/R reviewers on first submission
- QA turnaround time: internal reviews completed within defined SLA (e.g. 24–48 hours)
- Pre-launch error rate: <2% of launched assets requiring post-launch correction
- 100% accuracy on 2253 filings and regulatory submission packaging
- Documented QA standards maintained and current across all supported accounts
Most Important Things (MITs)
- Establish the pre-submission and pre-launch QA checkpoints as defined, repeatable stages in the creative workflow.
- Own the Veeva PromoMats workflow for assigned accounts — claims, annotations, references, and submissions operating cleanly from day one.
- Build and maintain the QA standards documentation (checklists, compliance reference guides, brand review criteria) the creative team works against.
- Develop a working rhythm with Creative Project Managers so that QA is a checkpoint in the pipeline, not a bottleneck.
Benefits & Perks
- Base salary + commission opportunities
- Robust Medical, Dental, Vision insurance plans with up to 100% employer contribution towards employee monthly premium
- 401(k) plan - 4% employer contribution matching
- Unlimited Time Off available on day one
- Up to 4 hours per quarter for paid Volunteer Time Off (VTO) towards philanthropic endeavors
- Fully flex work environment: full-remote, in-office, or hybrid
- A one time $100 USD Work From Home (WFH) stipend automatically added to your first paycheck
- Employee Assistance Program (EAP)
- 12 observed United States national holidays + 2 mental health recharge days per year
- Unlimited opportunities for growth & leadership within a rapidly growing firm
- Ongoing employee development programs for personal and professional growth (Hedgehog and Vital 5s)
- Quarterly awards including prize money and recognition for outstanding performance
- Opportunities to be involved in company DEI initiatives
Power Digital’s people and culture are at the core of our success, which is why diversity in our team’s backgrounds and experiences are paramount. We are an Equal Opportunity Employer and our employees are people with different strengths, experiences, and backgrounds, who strive to make an impact inside and outside of the workplace. Diversity not only includes race and gender identity, but also age, disability status, veteran status, sexual orientation, religion and many other parts of one’s identity. All of our employees' points of view are key to our success, and inclusion is everyone's responsibility.
Please be aware of fictitious job openings, consulting engagements, solicitations, or employment offers from suspicious sources. These engagements may be an attempt to obtain private information, or to induce you to pay a fee for services related to recruitment or training. Power Digital does NOT charge any application, processing, or training fee at any stage of the recruitment or hiring process. All genuine job openings will be posted on our careers page. If you have any doubts about the authenticity of any messaging behalf of Power Digital, please send us an email at recruiting@powerdigital.com before taking any further action in relation to the correspondence.
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Who's Hiring



Top Industries Hiring
- Technology & Software11
- Insurance5
- Accounting & Auditing4
- Healthcare & Medical Services4
- Construction & Real Estate3
What Employers Look For
The qualifications that appear most often in remote director of safety and compliance jobs.
- 7-10 years of progressive experience in environmental health, safety, or regulatory compliance
- Bachelor's degree in occupational health, environmental science, law, or a related field
- Certified Safety Professional (CSP) or Certified Compliance and Ethics Professional (CCEP) credential
- Deep working knowledge of OSHA standards, EPA regulations, or industry-specific compliance frameworks
- Proven experience developing, implementing, and managing enterprise-wide compliance programs
- Strong written communication skills for policy development, audit reports, and regulatory submissions
Tips for Your Remote Director of Safety and Compliance Job Search
Apply early to remote roles that fit
Migrate Mate lists remote director of safety and compliance openings from across the U.S. in one place, so you can find roles that match your background and apply directly. Remote postings often fill faster than on-site ones, so acting early matters.
Show async compliance leadership in your materials
Remote employers want to see that you can run audits, manage regulatory programs, and coordinate with distributed teams without in-person check-ins. Call out specific examples of async communication, remote team oversight, and digital compliance management in your resume and cover letter.
Get certified to stand out for remote roles
Certifications like a Certified Safety Professional, Certified Compliance and Ethics Professional, or OSHA credentials signal competence that remote hiring managers can verify without meeting you in person. They carry extra weight when you can't demonstrate your skills through on-site observation.
Prepare for competency-based remote interviews
Remote director interviews focus heavily on how you've handled compliance decisions independently, managed cross-functional stakeholders without face-to-face access, and kept programs on track across distributed teams. Have two or three detailed examples ready that show self-direction and results under minimal supervision.
Remote Director of Safety and Compliance Jobs: Frequently Asked Questions
How do I get a remote director of safety and compliance job?
Target remote-first companies and distributed organizations in regulated industries like healthcare, financial services, and technology, where compliance leadership is handled entirely off-site. Remote employers screen for strong written communication, the ability to manage audits and regulatory programs without in-person oversight, and comfort with async collaboration tools. Demonstrating that you've managed multi-site or cross-functional compliance programs independently gives you a clear edge.
Which companies hire remote director of safety and compliances?
Employers currently hiring remote director of safety and compliances include Humana, Centene, and Block, per current remote listings on Migrate Mate as of November 2026. These tend to be remote-first organizations, distributed enterprise teams, and companies in heavily regulated sectors that have built compliance infrastructure designed to operate without a central office.
Can you get a remote director of safety and compliance job with no experience?
Yes, but remote director-level roles are competitive and typically require demonstrated independence, since you won't have on-site managers guiding daily decisions. Entry paths include moving up from a remote compliance manager or EHS specialist role, contributing to distributed compliance projects, or showing measurable results from past regulatory work. Certifications like a CSP or CCEP and a portfolio of written compliance documentation help close the experience gap.
Do you need a degree for remote director of safety and compliance jobs?
Not always, though many remote employers in regulated industries prefer a bachelor's degree in occupational health, environmental science, law, or a related field. What remote hiring teams weigh heavily alongside formal education is hands-on compliance program leadership, relevant certifications such as a CSP, CHST, or CCEP, and a clear record of building or managing safety and compliance systems independently.
Which industries hire the most remote director of safety and compliances?
Remote director of safety and compliance roles concentrate in Technology & Software, Insurance, and Accounting & Auditing, based on current remote listings on Migrate Mate as of November 2026. These sectors hire remotely because their compliance programs are documentation-driven and policy-based, making them well suited to distributed teams that coordinate across multiple sites or business units without a shared physical office.
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