Remote Principal Solutions Engineer Jobs
Remote Principal Solutions Engineer jobs are available nationwide at employers like Humana, Sentara, and Fastly and other distributed teams, at every experience level. See the openings below and apply to the ones that match your experience.
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Datavant is the data collaboration platform trusted for healthcare. Guided by our mission to make the world's health data secure, accessible and actionable, we provide critical data solutions for organizations across the healthcare ecosystem - including providers, health plans, researchers, and life sciences companies. From fulfilling a single patient's request for their medical records to powering the AI revolution in healthcare, Datavanters are building the future of how data is connected and used to improve health.
By joining Datavant today, you're stepping onto a driven and highly collaborative team that is passionate about creating transformative change in healthcare.
What We're Looking For
The Principal, Commercial Life Sciences Solutions is responsible for helping Life Sciences customers understand, design, and adopt high-value data connectivity solutions across commercial, medical, market access, and real-world data use cases.
You will serve as a senior commercial pharma subject matter expert and pre-sales solutioning partner for Datavant's Life Sciences business. In this role, you will partner closely with Sales, Solutions Consulting, Product, Partnerships, Customer Success, Privacy, Legal, and Delivery teams to shape customer strategy, scope complex opportunities, and translate business needs into clear, executable Datavant solutions.
This role is highly customer-facing and requires deep understanding of how pharmaceutical organizations use data to support therapy adoption, launch planning, market access, patient and provider insights, medical affairs, HEOR, omnichannel engagement, healthcare marketing, and real-world evidence generation. You will help Datavant's commercial teams win and expand strategic Life Sciences accounts by bringing domain expertise, solution strategy, executive presence, and practical knowledge of privacy-preserving data connectivity.
Responsibilities of the Role
- Serve as a senior commercial pharma subject matter expert for Datavant's Life Sciences go-to-market team, with a focus on pre-sales solutioning, customer discovery, and strategic opportunity development.
- Partner with Client Partners, sales leaders, and solutions consultants to shape customer conversations across commercial analytics, market access, patient services, healthcare marketing, and digital/ad tech use cases.
- Lead discovery with pharmaceutical customers to understand their business objectives, stakeholder priorities, available data assets, privacy requirements, operational constraints, and desired outcomes.
- Translate customer goals into Datavant solution strategies that leverage privacy-preserving linkage, tokenization, data connectivity, real-world data partnerships, and health data exchange infrastructure.
- Design and communicate solution approaches for use cases such as patient journey analytics, launch planning, commercial analytics aggregation, adherence and persistence insights, market access evidence, medical affairs insights, provider targeting, omnichannel measurement, and privacy-preserving media activation.
- Help customers understand how Datavant can connect internal and external data assets across the healthcare ecosystem to create more complete, actionable views of patients, providers, products, and markets.
- Build executive-ready narratives that articulate the business value, feasibility, privacy posture, implementation path, and expected impact of connected data strategies.
- Support complex enterprise pursuits by developing solution hypotheses, shaping proposals, identifying risks, pressure-testing scope, and aligning internal teams around a credible and compelling approach.
- Collaborate with Product and Partnerships to identify market needs, solution gaps, customer feedback, and opportunities to convert demand into scalable Datavant offerings.
- Create reusable go-to-market assets, including solution playbooks, discovery guides, use case narratives, customer-facing materials, objection handling, case studies, and sales enablement.
- Act as a bridge between commercial teams and technical, product, privacy, and delivery teams to ensure customer-facing solutions are compelling, credible, feasible, and operationally executable.
- Represent Datavant in strategic customer workshops, executive briefings, industry forums, conferences, and thought leadership opportunities.
- Stay current on trends shaping commercial pharma data strategy, including real-world data adoption, healthcare media networks, clean rooms, first-party data strategy, privacy-preserving collaboration, tokenization, AI-enabled analytics, and the evolving life sciences data ecosystem.
Qualifications of the Role
- 10+ years of relevant experience in life sciences, pharmaceutical commercial strategy, commercial analytics, market access, healthcare data, real-world data, digital health, healthcare marketing, omnichannel marketing, or a related field.
- Deep understanding of life sciences companies, especially biopharma organizations, and how they use data across commercial, medical, market access, analytics, and evidence generation functions.
- Experience supporting pre-sales, enterprise solutioning, strategic consulting, customer advisory, business development, or complex commercial partnerships with pharmaceutical or healthcare customers.
- Strong fluency in real-world data and linked data use cases, including how claims, EHR, lab, mortality, specialty pharmacy, patient services, consumer, digital engagement, and first-party enterprise data can be connected to support commercial business decisions.
- Strong commercial instincts, including the ability to identify high-value use cases, understand buying centers, shape value propositions, support revenue growth, and help advance complex opportunities.
- Ability to lead senior customer conversations, uncover business needs, frame solution options, and guide customers from broad ambition to concrete, executable use cases.
- Ability to translate complex technical, data, and privacy concepts into clear business language for commercial, medical, analytics, and executive audiences.
- Highly consultative, hands on, and collaborative, with strong ability to influence cross-functional teams.
- Excellent communication, presentation, analytical, and organizational skills.
- Experience with Google suite of productivity applications, including Sheets, Slides, and Docs, as well as Salesforce.com or similar CRM tools.
- Self-motivated, able to take initiative, work efficiently and independently, and operate effectively in a fast-paced, dynamic environment.
- Ability to travel for strategic customer meetings, workshops, and industry events.
Bonus Points If
- You have worked directly inside, or closely alongside, a pharmaceutical commercial organization.
- You have experience with commercial analytics, medical affairs analytics, HEOR, market access, patient services, healthcare media, ad tech, or omnichannel measurement.
- You have sold, solutioned, or implemented enterprise data, analytics, SaaS, real-world data, or data connectivity solutions for pharmaceutical customers.
- You are familiar with the life sciences data vendor ecosystem, including RWD providers, analytics platforms, media partners, clean rooms, agencies, and data collaboration technologies.
- You have created scalable GTM materials such as solution playbooks, use case guides, sales enablement, customer-facing narratives, or executive thought leadership.
#LI-BC1
To ensure the safety of patients and staff, many of our clients require post-offer health screenings and proof and/or completion of various vaccinations such as the flu shot, Tdap, COVID-19, etc. Any requests to be exempted from these requirements will be reviewed by Datavant Human Resources and determined on a case-by-case basis. Depending on the state in which you will be working, exemptions may be available on the basis of disability, medical contraindications to the vaccine or any of its components, pregnancy or pregnancy-related medical conditions, and/or religion.
This job is not eligible for employment sponsorship.
Datavant is committed to a work environment free from job discrimination. We are proud to be an Equal Employment Opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, or other legally protected status. To learn more about our commitment, please review our EEO Commitment Statement here. Know Your Rights, explore the resources available through the EEOC for more information regarding your legal rights and protections. In addition, Datavant does not and will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay.
At the end of this application, you will find a set of voluntary demographic questions. If you choose to respond, your answers will be anonymous and will help us identify areas for improvement in our recruitment process. (We can only see aggregate responses, not individual ones. In fact, we aren't even able to see whether you've responded.) Responding is entirely optional and will not affect your application or hiring process in any way.
Datavant is committed to working with and providing reasonable accommodations to individuals with physical and mental disabilities. If you need an accommodation while seeking employment, please request it here, by selecting the 'Interview Accommodation Request' category. You will need your requisition ID when submitting your request, you can find instructions for locating it here. Requests for reasonable accommodations will be reviewed on a case-by-case basis.
For more information about how we collect and use your data, please review our Privacy Policy.
Datavant is the data collaboration platform trusted for healthcare. Guided by our mission to make the world's health data secure, accessible and actionable, we provide critical data solutions for organizations across the healthcare ecosystem - including providers, health plans, researchers, and life sciences companies. From fulfilling a single patient's request for their medical records to powering the AI revolution in healthcare, Datavanters are building the future of how data is connected and used to improve health.
By joining Datavant today, you're stepping onto a driven and highly collaborative team that is passionate about creating transformative change in healthcare.
What We're Looking For
The Principal, Commercial Life Sciences Solutions is responsible for helping Life Sciences customers understand, design, and adopt high-value data connectivity solutions across commercial, medical, market access, and real-world data use cases.
You will serve as a senior commercial pharma subject matter expert and pre-sales solutioning partner for Datavant's Life Sciences business. In this role, you will partner closely with Sales, Solutions Consulting, Product, Partnerships, Customer Success, Privacy, Legal, and Delivery teams to shape customer strategy, scope complex opportunities, and translate business needs into clear, executable Datavant solutions.
This role is highly customer-facing and requires deep understanding of how pharmaceutical organizations use data to support therapy adoption, launch planning, market access, patient and provider insights, medical affairs, HEOR, omnichannel engagement, healthcare marketing, and real-world evidence generation. You will help Datavant's commercial teams win and expand strategic Life Sciences accounts by bringing domain expertise, solution strategy, executive presence, and practical knowledge of privacy-preserving data connectivity.
Responsibilities of the Role
- Serve as a senior commercial pharma subject matter expert for Datavant's Life Sciences go-to-market team, with a focus on pre-sales solutioning, customer discovery, and strategic opportunity development.
- Partner with Client Partners, sales leaders, and solutions consultants to shape customer conversations across commercial analytics, market access, patient services, healthcare marketing, and digital/ad tech use cases.
- Lead discovery with pharmaceutical customers to understand their business objectives, stakeholder priorities, available data assets, privacy requirements, operational constraints, and desired outcomes.
- Translate customer goals into Datavant solution strategies that leverage privacy-preserving linkage, tokenization, data connectivity, real-world data partnerships, and health data exchange infrastructure.
- Design and communicate solution approaches for use cases such as patient journey analytics, launch planning, commercial analytics aggregation, adherence and persistence insights, market access evidence, medical affairs insights, provider targeting, omnichannel measurement, and privacy-preserving media activation.
- Help customers understand how Datavant can connect internal and external data assets across the healthcare ecosystem to create more complete, actionable views of patients, providers, products, and markets.
- Build executive-ready narratives that articulate the business value, feasibility, privacy posture, implementation path, and expected impact of connected data strategies.
- Support complex enterprise pursuits by developing solution hypotheses, shaping proposals, identifying risks, pressure-testing scope, and aligning internal teams around a credible and compelling approach.
- Collaborate with Product and Partnerships to identify market needs, solution gaps, customer feedback, and opportunities to convert demand into scalable Datavant offerings.
- Create reusable go-to-market assets, including solution playbooks, discovery guides, use case narratives, customer-facing materials, objection handling, case studies, and sales enablement.
- Act as a bridge between commercial teams and technical, product, privacy, and delivery teams to ensure customer-facing solutions are compelling, credible, feasible, and operationally executable.
- Represent Datavant in strategic customer workshops, executive briefings, industry forums, conferences, and thought leadership opportunities.
- Stay current on trends shaping commercial pharma data strategy, including real-world data adoption, healthcare media networks, clean rooms, first-party data strategy, privacy-preserving collaboration, tokenization, AI-enabled analytics, and the evolving life sciences data ecosystem.
Qualifications of the Role
- 10+ years of relevant experience in life sciences, pharmaceutical commercial strategy, commercial analytics, market access, healthcare data, real-world data, digital health, healthcare marketing, omnichannel marketing, or a related field.
- Deep understanding of life sciences companies, especially biopharma organizations, and how they use data across commercial, medical, market access, analytics, and evidence generation functions.
- Experience supporting pre-sales, enterprise solutioning, strategic consulting, customer advisory, business development, or complex commercial partnerships with pharmaceutical or healthcare customers.
- Strong fluency in real-world data and linked data use cases, including how claims, EHR, lab, mortality, specialty pharmacy, patient services, consumer, digital engagement, and first-party enterprise data can be connected to support commercial business decisions.
- Strong commercial instincts, including the ability to identify high-value use cases, understand buying centers, shape value propositions, support revenue growth, and help advance complex opportunities.
- Ability to lead senior customer conversations, uncover business needs, frame solution options, and guide customers from broad ambition to concrete, executable use cases.
- Ability to translate complex technical, data, and privacy concepts into clear business language for commercial, medical, analytics, and executive audiences.
- Highly consultative, hands on, and collaborative, with strong ability to influence cross-functional teams.
- Excellent communication, presentation, analytical, and organizational skills.
- Experience with Google suite of productivity applications, including Sheets, Slides, and Docs, as well as Salesforce.com or similar CRM tools.
- Self-motivated, able to take initiative, work efficiently and independently, and operate effectively in a fast-paced, dynamic environment.
- Ability to travel for strategic customer meetings, workshops, and industry events.
Bonus Points If
- You have worked directly inside, or closely alongside, a pharmaceutical commercial organization.
- You have experience with commercial analytics, medical affairs analytics, HEOR, market access, patient services, healthcare media, ad tech, or omnichannel measurement.
- You have sold, solutioned, or implemented enterprise data, analytics, SaaS, real-world data, or data connectivity solutions for pharmaceutical customers.
- You are familiar with the life sciences data vendor ecosystem, including RWD providers, analytics platforms, media partners, clean rooms, agencies, and data collaboration technologies.
- You have created scalable GTM materials such as solution playbooks, use case guides, sales enablement, customer-facing narratives, or executive thought leadership.
#LI-BC1
To ensure the safety of patients and staff, many of our clients require post-offer health screenings and proof and/or completion of various vaccinations such as the flu shot, Tdap, COVID-19, etc. Any requests to be exempted from these requirements will be reviewed by Datavant Human Resources and determined on a case-by-case basis. Depending on the state in which you will be working, exemptions may be available on the basis of disability, medical contraindications to the vaccine or any of its components, pregnancy or pregnancy-related medical conditions, and/or religion.
This job is not eligible for employment sponsorship.
Datavant is committed to a work environment free from job discrimination. We are proud to be an Equal Employment Opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, or other legally protected status. To learn more about our commitment, please review our EEO Commitment Statement here. Know Your Rights, explore the resources available through the EEOC for more information regarding your legal rights and protections. In addition, Datavant does not and will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay.
At the end of this application, you will find a set of voluntary demographic questions. If you choose to respond, your answers will be anonymous and will help us identify areas for improvement in our recruitment process. (We can only see aggregate responses, not individual ones. In fact, we aren't even able to see whether you've responded.) Responding is entirely optional and will not affect your application or hiring process in any way.
Datavant is committed to working with and providing reasonable accommodations to individuals with physical and mental disabilities. If you need an accommodation while seeking employment, please request it here, by selecting the 'Interview Accommodation Request' category. You will need your requisition ID when submitting your request, you can find instructions for locating it here. Requests for reasonable accommodations will be reviewed on a case-by-case basis.
For more information about how we collect and use your data, please review our Privacy Policy.
See All 518+ Remote Principal Solutions Engineer Jobs
Find roles that match your experience and apply in just a few clicks.
Find JobsRemote Principal Solutions Engineer Job Market
Who's Hiring
- Humana47
- Sentara30
- Fastly27
- Crowe LLP17
- Fivetran14
Top Industries Hiring
- Technology & Software209
- Healthcare & Medical Services73
- Insurance59
- Consulting & Professional Services36
- Cybersecurity29
What Employers Look For
The qualifications that appear most often in remote principal solutions engineer jobs.
- 5 or more years of solutions engineering, sales engineering, or pre-sales experience in a B2B technology environment
- Proven ability to lead complex proof-of-concept engagements and technical evaluations for enterprise accounts
- Deep expertise in at least one platform category such as cloud infrastructure, CRM, cybersecurity, or data integration
- Strong executive presentation skills with experience delivering architecture walkthroughs to C-suite stakeholders
- Experience mentoring junior solutions engineers and contributing to team playbooks or enablement programs
- Bachelor's degree in computer science, engineering, or a related technical field, or equivalent demonstrated experience
Tips for Your Remote Principal Solutions Engineer Job Search
Quantify your pre-sales impact on your resume
Principal solutions engineer resumes often look identical. Separate yours by quantifying deals closed with your technical support, proof-of-concept win rates, and the revenue tied to accounts you helped land or expand. Hiring managers scan for those numbers immediately.
Tailor your demo portfolio before applying
Many principal-level postings ask for a technical presentation or architecture walkthrough in the final round. Prepare a reusable demo environment in your specialty, whether that's Kubernetes, Salesforce, or a REST API stack, before you even send your first application.
Apply early to roles that fit
Migrate Mate lists principal solutions engineer openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Filter openings by your technical stack
Principal solutions engineer roles are highly stack-specific. A cloud-infrastructure opening at a hyperscaler demands different depth than a CRM-focused role at a SaaS vendor. Search by platform keyword, not just job title, so you apply only where your hands-on depth actually fits.
Prepare a whiteboard architecture walkthrough
Principal-level interviews almost always include a live system-design or solution-architecture exercise. Practice talking through a real integration challenge you solved, narrating your trade-off reasoning aloud. Interviewers at this level evaluate your thought process, not just your conclusion.
Negotiate scope, not just compensation
At the principal tier, your negotiation should address territory size, deal-stage involvement, and access to product roadmap input, not only base pay. Clarify which decisions you own independently versus which require sign-off before you accept any offer.
Remote Principal Solutions Engineer Jobs: Frequently Asked Questions
How do I get a remote principal solutions engineer job?
Target companies that already run distributed teams, since they hire remotely by default and know how to onboard someone they never meet in person. Remote principal solutions engineer employers screen hard for self-direction and clear written communication on top of the core skills, so show evidence you can own work without someone over your shoulder. Apply to the openings above that match your experience.
Which companies hire remote principal solutions engineers?
Remote principal solutions engineer roles are posted by Humana, Sentara, and Fastly and others right now, based on current remote listings on Migrate Mate as of June 2026. Remote-first firms and large companies running distributed teams post the most remote principal solutions engineer roles.
Can you get a remote principal solutions engineer job with no experience?
Yes, but it is harder than an on-site role, because remote work expects you to operate independently from the start. Entry-level remote principal solutions engineer openings do exist, especially at remote-first companies, and a portfolio of real work helps more than a long resume. Applying broadly to the roles that fit improves your odds.
Do you need a degree for remote principal solutions engineer jobs?
Not always. Many employers hire remote principal solutions engineers on demonstrated skills and prior work rather than a specific degree, though some larger companies still prefer one. Showing relevant results matters more than a credential for most remote principal solutions engineer roles.
Which industries hire the most remote principal solutions engineers?
Most remote principal solutions engineer openings sit in Technology & Software, Healthcare & Medical Services, and Insurance, per current remote listings on Migrate Mate as of June 2026. These sectors run distributed teams and hire principal solutions engineers remotely most consistently.
See All 518+ Remote Principal Solutions Engineer Jobs
Find roles that match your experience and apply in just a few clicks.
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