Research Jobs in San Mateo, CA
Research jobs in San Mateo are concentrated in the Hillsdale and downtown corridors, across life sciences, technology, and financial services. Demand is strong and active, with employers like Skild AI, BigHat Biosciences, and Cognitiv posting openings regularly. Find a role that fits below and apply directly.
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We are WisdomAI.
We exist to help people unlock clarity from complexity.
WisdomAI builds AI-powered analytics that put answers directly in the hands of the people closest to the business. Our platform doesn’t just surface insights — it explains the why behind them, helping teams move from data to decisions with speed, confidence, and context.
We’re trusted by companies like Cisco, Patreon, and Rubrik — and we’re just getting started.The problems here are hard, and the expectations are high. Our team is energized by both. If you’re compelled by ambitious problems, high standards, and meaningful ownership, you’ll thrive here.
We're looking for exceptional Research Engineers who enjoy turning cutting-edge AI research into production systems used by enterprise customers. This role sits at the intersection of research and engineering - you'll design experiments, invent new approaches, and ship systems that directly impact customer experience.
This role is based out of our San Mateo office.
What You'll Do
Design and run rigorous experiments, including ablations, benchmarking, and error analysis, to improve NL-to-SQL generation, retrieval, ranking, and agentic reasoning.
Advance multi-turn conversational understanding through improved context retention, entity resolution, conversational memory, and intelligent clarification strategies.
Build robust evaluation frameworks, including automated benchmarks, regression suites, and LLM-as-a-judge methodologies to measure and improve model quality.
Prototype, validate, and productionize ML techniques, including fine-tuning, distillation, retrieval optimization, and agent architectures.
Evaluate emerging foundation models and AI research, rapidly translating promising advances into production experiments.
Contribute to the broader AI community through technical reports, or conference talks.
What We're Looking For
5+ years of experience in applied machine learning, NLP, large language models, or AI research, with a proven track record of shipping production AI systems.
Master's degree in Computer Science, Machine Learning, Artificial Intelligence, NLP, or a related field required; PhD is a strong plus.
Deep experience with modern LLMs and agent architectures.
Strong software engineering skills with production-quality Python and experience using modern AI frameworks.
Demonstrated ability to design rigorous evaluation frameworks, benchmark models, and make data-driven decisions balancing quality, latency, cost, and reliability.
Demonstrated ability to improve model cost/quality through experimentation—including retrieval optimization, fine-tuning, distillation, inference optimization, and agent design.
Nice to Have
Publications at leading AI or NLP conferences (ACL, EMNLP, NeurIPS, ICML, ICLR, NAACL, CVPR) or meaningful contributions to open-source AI projects.
Experience adapting foundation models and deploying production-scale LLM systems.
You'll Thrive Here If You...
Think scientifically and validate ideas through rigorous experimentation.
Care equally about elegant research and measurable production impact.
Enjoy digging into production failure cases to uncover new research directions.
Balance curiosity with pragmatism, you know when to explore and when to ship.
Want your work to directly influence how enterprises interact with AI every day.
Why WisdomAI
We're building foundational technology at the intersection of large language models, reasoning, and enterprise analytics. Our platform empowers people closest to the business with trustworthy, conversational access to insights hidden across their organization's data.
You'll join a team of engineers and researchers tackling some of the hardest problems in applied AI—from structured reasoning and conversational memory to retrieval, planning, and trustworthy analytical agents.
You'll have the freedom to explore bold ideas, the infrastructure to validate them quickly, and the opportunity to see your work deployed in production for leading enterprises.
If solving unsolved AI problems while shipping real-world impact excites you, we'd love to build with you.
Additional Details:
Compensation: The expected starting base salary for this role is $280,000+, in addition to equity and benefits. Final compensation will be determined based on factors including experience, technical depth, interview performance, and overall alignment with the role. We believe in paying competitively for exceptional talent and leveling compensation based on demonstrated impact.
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Our CRAFT
CRAFT isn’t a list of aspirational values. It’s how we hire, how we promote, how we resolve hard calls, and how we stay honest with ourselves.
C — Customer trust. Everything starts here. We listen carefully, act with integrity, and respond with urgency. Delight is downstream of trust — never the other way around.
R — Relentless on outcomes. We move with urgency, take initiative, and see things through. Effort isn’t the measure — results are. If something isn’t working, we change the approach now.
A — Authenticity. We say the hard things, directly and with respect. We also show up as full humans. That combination is how trust is earned and how we grow together.
F — First principles, grounded in reality. We don’t accept “that’s how it’s done.” We strip problems to what’s actually true and build up from there — then validate quickly and let real-world results decide.
T — Transparency. We share the why, not just the what. When something can’t be shared, we say so. We’re one team — information flows so we can do our best work and challenge each other when we’re wrong.
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Equal opportunity employer
WisdomAI is an equal opportunity employer. We do not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, or any other characteristic protected by applicable law. We are committed to building a diverse, inclusive team where everyone can do their best work.
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Who's Hiring



Top Industries Hiring
- Technology & Software
- Science & Research
- Artificial Intelligence
Research Jobs in San Mateo: Frequently Asked Questions
How do I get a research job in San Mateo?
Focus on the sectors that drive the most local hiring: biotech and life sciences companies clustered near the Bay Meadows and Hillsdale areas, technology firms along the 101 corridor, and financial services firms anchored downtown. Candidates who demonstrate hands-on data analysis experience, familiarity with research methodologies relevant to their target sector, and knowledge of local industry players tend to stand out. Tailoring your application to a specific company's research focus area gives you a clear edge.
Which companies hire researchs in San Mateo?
San Mateo research roles are posted by Skild AI, BigHat Biosciences, and Cognitiv and others right now, based on current listings on Migrate Mate as of July 2026. San Mateo attracts a mix of established life sciences firms, mid-size technology companies, and financial services organizations, all of which maintain active research functions.
Are there remote research jobs in San Mateo?
Yes, though it depends heavily on the type of research work: analytical, desk-based, and quantitative roles are far more remote-friendly than lab-based or field research positions. About 33% of research openings tied to San Mateo are remote or hybrid as of July 2026, reflecting broader flexibility in tech and finance research. Roles in market research, data research, and financial analysis are the most likely to offer remote or hybrid arrangements locally.
How can I get a research job in San Mateo with little or no experience?
The most realistic entry path is targeting research assistant or junior analyst roles at San Mateo's mid-size biotech and technology companies, which often hire candidates with strong academic project experience in place of direct industry work. Local contract research organizations and financial services firms also bring on entry-level researchers for data gathering and analysis support. Building familiarity with tools common in your target sector, such as statistical software or laboratory platforms, and highlighting any relevant coursework or independent projects gives early-career candidates a concrete advantage.
Which industries hire the most researchs in San Mateo?
The sectors hiring the most researchs in San Mateo are Technology & Software, Science & Research, and Artificial Intelligence, based on current listings on Migrate Mate as of July 2026. San Mateo's position between Silicon Valley and San Francisco means technology and life sciences companies maintain particularly deep research functions, while the concentration of financial services firms downtown sustains steady demand for market and investment research roles.
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