Research Technician Jobs in California
Research Technician jobs in California represent one of the most active markets in the country, concentrated in biotechnology, pharmaceutical research, academic science, and public health laboratories across the San Francisco Bay Area, San Diego, and Los Angeles. Employers like Genentech, UC San Diego Health, and Kaiser Permanente maintain consistent demand for research technicians, particularly those with backgrounds in molecular biology, clinical laboratory science, and environmental testing. Openings range from entry-level bench positions to senior lab technician roles supporting principal investigators and clinical trials. Scan the live roles below and apply to whichever ones fit.
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The USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, Titus Family Department of Clinical Pharmacy, is seeking a Research Lab Technician II to support ongoing studies in immunogenomics, cancer genomics and therapeutics.
We are a translational genomics and experimental therapeutics lab focused on identifying and investigating novel therapeutic targets in acute myeloid leukemia (AML) and developing new therapeutic strategies. We seek a highly motivated, detail-oriented individual to perform molecular, cellular, and in vivo experiments and support the day-to-day operation of the laboratory.
Responsibilities
- Process and run quality control on next-generation sequencing data (e.g., RNA-seq, whole-exome/genome sequencing, ATAC-seq, ChIP-seq, single-cell sequencing) using established pipelines
- Perform downstream analyses, including differential expression, variant calling and annotation, pathway enrichment, and clustering, under the guidance of the Principal Investigator and senior lab members
- Analyze data from high-throughput drug screens, flow cytometry, and preclinical mouse studies; perform basic statistical analyses
- Mine public ‘omics’ resources (e.g., TCGA, BeatAML, GEO, DepMap) to support target discovery and validation
- Maintain, document, and update analysis pipelines and scripts using version control
- Organize and manage lab datasets, sample metadata, and clinical annotations in compliance with IRB and data security requirements
- Run jobs on USC’s high-performance computing cluster and manage data storage
- Prepare figures, tables, and summaries of results for lab meetings, presentations, and manuscripts
Minimum Preferred Qualifications
- Bachelor’s degree in biology, molecular biology, biochemistry, immunology, or a related field
- Hands-on laboratory experience with routine molecular biology and cell culture techniques
- Excellent organizational, record-keeping, and communication skills
- Ability to work both independently and as part of a team
Preferred Qualifications
- Master’s degree or 1–2 years of research laboratory experience
- Experience with flow cytometry, NGS sample preparation, or high-throughput assays
- Experience with mouse handling and in vivo studies
- Familiarity with basic data analysis tools (e.g., R, Python, GraphPad Prism) or interest in learning bioinformatics
- Background in cancer biology or hematologic malignancies
Applicants should attach the following:
- Cover letter describing research experience and interests
- Résumé or CV
- Names and contact information for two to three references
The hourly rate range for this position is $25.71 - $28.32. When extending an offer of employment, the University of Southern California considers factors such as (but not limited to) the scope and responsibilities of the position, the candidate’s work experience, education/training, key skills, internal peer equity, federal, state, and local laws, contractual stipulations, grant funding, as well as external market and organizational considerations.
Minimum Education: Associate's degree, Specialized/technical training, Combined experience/education as substitute for minimum education Minimum Experience: 2 years Minimum Field of Expertise: Working knowledge of laboratory equipment and research protocols. Knowledge of computer analysis techniques and ability to provide routine analysis and interpretation of research data.
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Find Research Technician JobsResearch Technician Jobs by City in California
Where California roles are concentrated, by current openings.
Research Technician Job Market in California
A snapshot from current California openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Science & Research
What California Employers Look For
The qualifications that appear most often in research technician jobs across California.
- Bachelor's degree in biology, chemistry, biochemistry, or a closely related life science field
- Hands-on laboratory experience with techniques such as PCR, cell culture, or ELISA
- Familiarity with laboratory safety protocols, GLP, and California OSHA regulations
- Experience maintaining accurate laboratory notebooks and scientific data records
- Ability to operate and troubleshoot standard lab instrumentation and analytical equipment
- Strong written and verbal communication skills for reporting results to research teams
Research Technician Jobs in California: Frequently Asked Questions
How do you become a research technician in California?
Most research technician positions in California require at minimum a bachelor's degree in a life science, chemistry, or engineering discipline. Roles in clinical or public health laboratories may require a California State Department of Public Health laboratory scientist or laboratory technician license, issued through the CDPH Laboratory Field Services program. Academic and biotech positions typically prioritize hands-on research experience gained through undergraduate labs, internships, or university research programs alongside the degree.
Which companies hire research technicians in California?
Companies currently hiring research technicians in California include Keck Medicine of USC, University of Southern California, and California Institute of Technology, per current listings on Migrate Mate as of November 2026. California's dense concentration of biotech firms in the Bay Area and San Diego, combined with major university health systems and public agencies, makes it one of the broadest hiring markets for this role in the country.
Which California cities have the most research technician jobs?
Los Angeles, Pasadena, and San Diego consistently lead California for research technician openings. The San Francisco Bay Area draws the highest volume from biotech and pharmaceutical headquarters clustered in South San Francisco, Berkeley, and Emeryville, while San Diego's Torrey Pines and Sorrento Valley corridors anchor Southern California demand, and Los Angeles reflects large academic medical centers and county public health laboratories.
Are there remote research technician jobs in California?
Yes, but they are rare. Research technician work is primarily hands-on and laboratory-based, so fully remote positions are uncommon by the nature of the role. About 0% of research technician openings tied to California are remote or hybrid as of November 2026, and those tend to cover data analysis, bioinformatics support, or administrative research coordination rather than bench or field work.
How can I get hired as a research technician in California with little or no experience?
The most realistic entry path is applying to research assistant or laboratory assistant postings at University of California campuses, California State University campuses, or large health systems like UCLA Health and UCSF, which regularly hire candidates without professional experience for support roles in active research labs. Completing relevant coursework in molecular techniques and volunteering in a university lab or community college research program builds the hands-on record California employers expect. A CDPH laboratory technician license, where the role qualifies, also gives entry-level candidates a competitive edge.
Where can I find and apply to research technician jobs in California?
You can find and apply to research technician jobs in California on Migrate Mate, which lists current California openings across biotechnology, healthcare, academic research, and environmental science. Search the listings for roles that match your background and experience level, then apply directly to the ones that fit.
See All 39 Research Technician Jobs in California
Find roles in California that match your experience and apply in just a few clicks.
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