Senior Clinical Data Manager Jobs in District of Columbia
Senior Clinical Data Manager jobs in District of Columbia are concentrated in the federal health corridor anchored by Washington, D.C., where agencies, contract research organizations, and biotech firms drive steady demand for professionals with expertise in clinical trial data governance, CDISC standards, and regulatory submissions. The largest employers with a lasting presence here include ICON plc, ICF International, and Leidos, all of which maintain substantial clinical operations tied to federal health contracts. Demand is especially strong for candidates with oncology, infectious disease, and government-sponsored trial experience. Scan the live roles below and apply to whichever ones fit.
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Sr Enterprise Data Architect
Active Top Secret or DHS Clearance.
Location: Washington, D.C. - Hybrid
Job Description:
Senior Database Engineer with 10+ years of experience in data governance to design, implement, and manage enterprise-wide data governance frameworks.
The candidate must be able to establish and maintain robust metadata, data lineage, and master data management practices while ensuring alignment with organizational policies, standards, and regulatory requirements.
The position also demands hands-on experience integrating Collibra with modern data platforms, supporting business users in self-service data discovery, and leveraging automation and AI/ML capabilities to enhance data quality, streamline metadata ingestion, and optimize governance processes.
Data Governance Collibra Integration
Define and implement data governance frameworks using Collibra.
Ensure data cataloging, data lineage, and data stewardship are maintained within Collibra.
Work with business and IT teams to establish data policies, standards, and ownership.
Metadata Master Data Management (MDM)
Design and maintain enterprise metadata models and ensure metadata tagging aligns with Collibra.
Oversee data classification, business glossaries, and data dictionaries within Collibra.
Collaborate with teams to ensure consistent and accurate master data across systems.
Data Architecture Strategy
Define data models, standards, and principles for structured and unstructured data.
Work on data integration strategies to align disparate data sources with governance frameworks.
Ensure compliance with data privacy and security regulations like GDPR, CCPA, and federal standards.
Team Collaboration Stakeholder Management
Partner with CDO, Data Stewards, Engineers, and Analysts to ensure data usability and trustworthiness.
Provide technical guidance on how Collibra integrates with data platforms (e.g., Snowflake, Databricks, AWS, etc.).
Train and support business users on self-service data discovery using Collibra.
Automation AI Integration
Leverage AI/ML capabilities within Collibra for data quality monitoring and anomaly detection.
Automate metadata ingestion, data lineage, and governance processes to improve efficiency.
QUALIFICATIONS
Bachelor's Degree in Computer Science, Engineering, or a related field.
10+ years of relevant experience.
Strong knowledge of metadata management, data lineage, and master data management (MDM) practices.
Hands-on expertise integrating Collibra (or similar, e.g., Informatica) with modern data platforms (e.g., Snowflake, Databricks, AWS).
Solid understanding of data architecture principles, data modeling, and data integration strategies.
Familiarity with data privacy and regulatory standards such as GDPR, CCPA, and federal compliance requirements.
Ability to collaborate with cross-functional stakeholders and provide guidance on data governance best practices.
Strong communication skills and ability to lead and mentor a development team.
Preferred:
Hands-on experience with Collibra.
Hands-on experience integrating Collibra with BI/analytics tools (e.g., Tableau, Power BI).
Prior experience supporting large-scale enterprise data modernization initiatives.
Clearance:
U.S. Citizen; Active DHS Clearance, DoD Top Secret Clearance, or Q-level Clearance.
See All 274+ Senior Clinical Data Manager Jobs in District of Columbia
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Find JobsSenior Clinical Data Manager Jobs by City in District of Columbia
Where District of Columbia roles are concentrated, by current openings.
Senior Clinical Data Manager Job Market in District of Columbia
A snapshot from current District of Columbia openings, updated as new roles post.
Who's Hiring
- Booz Allen Hamilton18

- Meta9

- BigBear.ai7

- Guidehouse6

- Parsons5

Top Industries Hiring
- Technology & Software27
- Consulting & Professional Services16
- Education3
- Non-Profit & Social Services3
- Healthcare & Medical Services3
What District of Columbia Employers Look For
The qualifications that appear most often in senior clinical data manager jobs across District of Columbia.
- Bachelor's or advanced degree in life sciences, health informatics, or a related field
- Minimum five years of clinical data management experience including trial oversight
- Proficiency with industry-standard CDM platforms such as Medidata Rave or Oracle Clinical
- Strong working knowledge of CDISC standards including CDASH and SDTM
- Experience managing data for FDA-regulated studies and supporting regulatory submissions
- Demonstrated ability to lead data management teams and mentor junior staff
Senior Clinical Data Manager Jobs in District of Columbia: Frequently Asked Questions
How do you become a senior clinical data manager in District of Columbia?
The path to a senior clinical data manager role in D.C. typically starts with a bachelor's degree in life sciences, health informatics, or a related field, followed by several years in clinical data or clinical operations. While D.C. has no state-issued license specific to this role, many employers here favor candidates holding the Society of Clinical Data Management's Certified Clinical Data Manager credential, which signals competency recognized across the federal contracting and CRO ecosystem that dominates local hiring.
Which companies hire senior clinical data managers in District of Columbia?
District of Columbia senior clinical data manager roles are posted by Booz Allen Hamilton, Meta, and BigBear.ai and others right now, based on current listings on Migrate Mate as of July 2026. D.C.'s concentration of federal health agencies and large government contractors makes it a consistent market for this role across both full-time and contract positions.
Which District of Columbia cities have the most senior clinical data manager jobs?
Washington and District of Columbia account for the most senior clinical data manager openings in District of Columbia. Washington, D.C. itself dominates because of its density of federal agencies, CROs, and health-focused contractors, while nearby Maryland and Virginia suburbs like Bethesda and Rockville generate additional openings tied to NIH-affiliated organizations and pharmaceutical firms with regional headquarters in the broader metro area.
Are there remote senior clinical data manager jobs in District of Columbia?
Yes, and more than most fields. About 65% of senior clinical data manager openings tied to District of Columbia are remote or hybrid as of July 2026, reflecting the desk-based and software-driven nature of the work. Data review, query management, and protocol development are the functions most commonly performed fully remotely, while study kickoff meetings and sponsor audits tend to require an in-person presence.
How can I get hired as a senior clinical data manager in District of Columbia with little or no experience?
The most realistic entry point is a clinical data coordinator or data associate role at a CRO or federal health contractor in the D.C. area, where employers like ICON plc, Leidos, and ICF International regularly bring on junior staff for NIH-funded or government-sponsored trials. Building hands-on experience with CDISC standards and earning the entry-level CCDM credential gives candidates a measurable edge when applying. Adjacent roles in clinical operations, biostatistics coordination, or medical coding at D.C.-area research hospitals also provide lateral pathways into CDM.
Where can I find and apply to senior clinical data manager jobs in District of Columbia?
You can find and apply to senior clinical data manager jobs in District of Columbia on Migrate Mate, which lists current D.C. openings from employers actively hiring right now. Search the listings, find the roles that match your background and preferences, and apply directly to the ones that fit.
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