Senior Clinical Data Manager Jobs in Kansas City, MO
Senior Clinical Data Manager jobs in Kansas City are in active demand, concentrated in the Country Club Plaza corridor, the Crossroads district, and the suburban campuses of Overland Park and Lenexa across clinical research organizations, pharmaceutical companies, and health systems. Employers hiring right now include Olsson, Google, and DHL. See the openings below and apply to the ones that match your experience.
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Showing 5 of 64+ Senior Clinical Data Manager jobs
This is an on-site role based in Columbia, MO or Kansas City, MO.
Candidates must be within driving distance and able to work in-office regularly. Remote work is not available for this position.
It’s a broad role with real ownership, which is both the appeal and the challenge: there isn’t a senior engineer above you reviewing every decision. We’re looking for someone ready to own the whole platform and confident enough to ask questions when needed.
What you’ll do:
Own the data pipelines
- Manage automated replication and ingestion into the warehouse
- Monitor performance, troubleshoot failures, and handle schema changes
- Add new data sources as business needs evolve
Own the platform architecture
- Maintain and evolve the cloud warehouse architecture
- Define layering, naming conventions, performance standards, and cost efficiency
- Ensure scalability across multiple subsidiaries
Own the data modeling
- Design and maintain dimensional models (facts and dimensions)
- Partner directly with Finance, HR, and Operations leaders to translate business needs into data structures
- Build models that support accurate, decision-ready reporting
Ensure data trust and reliability
- Build in testing, documentation, and data quality checks
- Maintain clear data lineage and transparency
- Ensure stakeholders trust the accuracy of reporting
What we’re looking for
- Strong data engineering fundamentals — clean, maintainable SQL and Python
- Experience building and operating production data pipelines
- Hands-on experience with a cloud data warehouse (BigQuery preferred; Snowflake, Redshift, or similar acceptable) Experience with transformation frameworks (dbt strongly preferred) and layered data architecture (raw staging
- modeled)
- Solid understanding of dimensional modeling (facts vs. dimensions, star schema design)
- Experience with ELT / data replication tools (Fivetran or similar)
- Ability to partner with non-technical stakeholders and translate business needs into scalable data solutions
- Comfortable owning decisions and operating independently
Nice to have
- Experience with Google Cloud Platform (Cloud Run, Cloud SQL/PostgreSQL, Pub/Sub, Cloud Scheduler, Secret Manager)
- Experience integrating ERP systems (Viewpoint Vista or similar) and HCM platforms (Workday)
- Familiarity with CI/CD-driven data workflows and version-controlled transformations
- Experience managing warehouse cost optimization
- Background in construction, engineering, or operations-heavy industries
Reminders:
- This is strictly an on-site role
- Must be located within driving distance of Columbia, MO or Kansas City, MO
- No remote or hybrid work options available
Who Thrives Here:
The person who does well here likes owning the whole thing rather than a corner of it, cares more about whether the numbers are right than whether the pipeline is clever, and would rather ship a model the finance team actually uses than a perfect one nobody asked for. You're comfortable being the person who knows how the data fits together, and you treat "the business owner doesn't quite know what they want yet" as part of the job rather than a blocker.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)
This is an on-site role based in Columbia, MO or Kansas City, MO.
Candidates must be within driving distance and able to work in-office regularly. Remote work is not available for this position.
It’s a broad role with real ownership, which is both the appeal and the challenge: there isn’t a senior engineer above you reviewing every decision. We’re looking for someone ready to own the whole platform and confident enough to ask questions when needed.
What you’ll do:
Own the data pipelines
- Manage automated replication and ingestion into the warehouse
- Monitor performance, troubleshoot failures, and handle schema changes
- Add new data sources as business needs evolve
Own the platform architecture
- Maintain and evolve the cloud warehouse architecture
- Define layering, naming conventions, performance standards, and cost efficiency
- Ensure scalability across multiple subsidiaries
Own the data modeling
- Design and maintain dimensional models (facts and dimensions)
- Partner directly with Finance, HR, and Operations leaders to translate business needs into data structures
- Build models that support accurate, decision-ready reporting
Ensure data trust and reliability
- Build in testing, documentation, and data quality checks
- Maintain clear data lineage and transparency
- Ensure stakeholders trust the accuracy of reporting
What we’re looking for
- Strong data engineering fundamentals — clean, maintainable SQL and Python
- Experience building and operating production data pipelines
- Hands-on experience with a cloud data warehouse (BigQuery preferred; Snowflake, Redshift, or similar acceptable) Experience with transformation frameworks (dbt strongly preferred) and layered data architecture (raw staging
- modeled)
- Solid understanding of dimensional modeling (facts vs. dimensions, star schema design)
- Experience with ELT / data replication tools (Fivetran or similar)
- Ability to partner with non-technical stakeholders and translate business needs into scalable data solutions
- Comfortable owning decisions and operating independently
Nice to have
- Experience with Google Cloud Platform (Cloud Run, Cloud SQL/PostgreSQL, Pub/Sub, Cloud Scheduler, Secret Manager)
- Experience integrating ERP systems (Viewpoint Vista or similar) and HCM platforms (Workday)
- Familiarity with CI/CD-driven data workflows and version-controlled transformations
- Experience managing warehouse cost optimization
- Background in construction, engineering, or operations-heavy industries
Reminders:
- This is strictly an on-site role
- Must be located within driving distance of Columbia, MO or Kansas City, MO
- No remote or hybrid work options available
Who Thrives Here:
The person who does well here likes owning the whole thing rather than a corner of it, cares more about whether the numbers are right than whether the pipeline is clever, and would rather ship a model the finance team actually uses than a perfect one nobody asked for. You're comfortable being the person who knows how the data fits together, and you treat "the business owner doesn't quite know what they want yet" as part of the job rather than a blocker.
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)
See All 64 Senior Clinical Data Manager Jobs in Kansas City
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Find JobsSenior Clinical Data Manager Job Market in Kansas City
Who's Hiring
- Olsson14
- Google4
- DHL3
- CBRE3
- Lockton Companies3
Top Industries Hiring
- Technology & Software7
- Consulting & Professional Services7
- Insurance3
- Artificial Intelligence3
- Education1
Senior Clinical Data Manager Jobs in Kansas City: Frequently Asked Questions
How do I get a senior clinical data manager job in Kansas City?
The strongest path is targeting Kansas City's clinical research organizations, regional health systems, and the pharmaceutical and medical device companies concentrated in the Overland Park and Lenexa suburban corridor. Candidates who can demonstrate hands-on experience with EDC platforms and a history of managing complex, multi-site trials stand out here. Familiarity with the oncology and cardiovascular therapeutic areas common in local sponsored research programs gives an additional edge in this market.
Which companies hire senior clinical data managers in Kansas City?
Employers hiring senior clinical data managers in Kansas City right now include Olsson, Google, and DHL, based on current listings on Migrate Mate as of July 2026. The Kansas City market draws from a mix of mid-size clinical research organizations, regional hospital networks with active research divisions, and pharmaceutical and biotech firms with operations on the Missouri-Kansas border.
Are there remote senior clinical data manager jobs in Kansas City?
Yes, and senior clinical data management is among the more remote-compatible roles in clinical research since the core work centers on database oversight, data review, and vendor communication rather than on-site patient contact. About 59% of senior clinical data manager openings tied to Kansas City are remote or hybrid as of July 2026, reflecting broader industry trends. Database build and close-out phases are the tasks most commonly performed remotely in Kansas City-based studies.
How can I get a senior clinical data manager job in Kansas City with little or no experience?
The most realistic entry point is a clinical data coordinator or data associate role at one of Kansas City's clinical research organizations or hospital-based research programs, where you can build EDC and regulatory experience directly. Employers at research-active systems like the University of Kansas Health System and local CRO offices regularly hire coordinators who move into management tracks within a few years. Earning a CCDM credential while working in a coordinator role accelerates that progression significantly in this market.
Which industries hire the most senior clinical data managers in Kansas City?
The sectors hiring the most senior clinical data managers in Kansas City are Technology & Software, Consulting & Professional Services, and Insurance, based on current listings on Migrate Mate as of July 2026. Kansas City's concentration of regional health systems, contract research organizations, and pharmaceutical operations along the state line corridor makes those sectors the primary and most consistent source of local openings.
See All 64 Senior Clinical Data Manager Jobs in Kansas City
Find roles in Kansas City that match your experience and apply in just a few clicks.
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