Senior Clinical Data Manager Jobs in St. Louis, MO
Senior Clinical Data Manager jobs in St. Louis are in active demand, concentrated in the Cortex Innovation Community, Midtown Medical District, and Maryland Heights corridor across clinical research, biopharmaceuticals, and medical device firms. Employers hiring right now include Esri, Edward Jones, and Stellar Solutions. Find a role that fits below and apply directly.
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Derex Technologies Inc specializes in providing IT consulting, staffing solutions and software services. Globally headquartered in Harrison New Jersey since 1996 Derex delivers the highest quality technology professionals and an array of customized IT talent solutions designed to improve productivity and drive results to global clients throughout North America.
With over two decades of unparalleled experience, Derex provides supports to its clientele, across such industries as Systems Integration, Banking and Finance, Telecommunications, Pharmaceutical and Life Sciences, Energy, Healthcare, Technology, Transportation, and local and federal Government agencies.
Job Description
Position: Senior MS Fabric Data Engineer - Azure
Location: St Louis, MO - Fully Onsite
Experience in the Financial or Banking Sector - Mandatory
Job Summary
The ideal candidate will have a deep understanding of Microsoft data services, including Azure Fabric, Azure Data Factory (ADF), Azure Synapse, and ETL/ELT processes. This role focuses on designing, developing, and maintaining cloud-based data pipelines and solutions to drive our analytics and business intelligence capabilities.
- Lead modernization of legacy data platforms, migrating ETL/ELT and ingestion frameworks to cloud (Azure/AWS).
- Own end-to-end data solution architecture, ensuring scalability, security, and business alignment.
- Provide technical leadership, mentoring teams and enforcing best practices.
- Drive decision-making in ambiguous environments, proactively mitigating risks and constraints.
- Implement data governance, security, and compliance frameworks (PII, regulatory standards).
- Collaborate with stakeholders to translate business needs into scalable data solutions.
- Architect and integrate data from multiple sources into high-performing cloud platforms.
- Design and optimize ETL/ELT pipelines using ADF, Databricks, Spark, and SSIS.
- Partner with analytics and BI teams to support reporting and advanced analytics use cases.
- Ensure data quality through profiling, validation, and monitoring processes.
- Establish CI/CD and DevOps practices for data engineering workflows.
- Monitor and optimize pipeline performance, scalability, and cost efficiency.
- Lead testing (unit, system, integration) and maintain comprehensive documentation.
- Drive continuous improvement and innovation across tools, frameworks, and architecture.
Required Skills and Qualifications:
- 12+ years of experience in designing and implementing data warehouse and analytics solutions (on-premises and cloud).
- Expertise in data warehousing concepts (ETL/ELT, data quality management, privacy/security, MDM) with hands-on experience using ADF, Data Factory, SSIS, and related tools.
- Experience with cloud data and cloud-native data lakes/warehouses. Microsoft Azure services (Fabric Lakehouse, ADF, Data Factory, Synapse, etc.).
- Experience in Python, Scala, or Java for use with distributed processing and analytics, such as Spark.
Familiarity with CI/CD practices and tools such as Azure DevOps, Git, or Jenkins.
Regards,
Manoj Goud
Derex Technologies INC
Contact : 973-834-5005 Ext 206
Additional Information
All your information will be kept confidential according to EEO guidelines.
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Find JobsSenior Clinical Data Manager Job Market in St. Louis
Who's Hiring
- Esri4
- Edward Jones4
- Stellar Solutions4
- Equifax3
- Core & Main3
Top Industries Hiring
- Technology & Software11
- Consulting & Professional Services8
- Education2
- Construction & Real Estate2
- Banking & Financial Services2
Senior Clinical Data Manager Jobs in St. Louis: Frequently Asked Questions
How do I get a senior clinical data manager job in St. Louis?
Focus your search on the Cortex Innovation Community, the Midtown Medical District, and the research campuses stretching toward Clayton and Maryland Heights, where clinical research organizations, biopharma firms, and academic medical centers concentrate their data management hiring. Candidates with hands-on experience in EDC platforms, CDISC standards, and Phase II or Phase III trial oversight stand out in this market. Networking through Washington University's clinical research community and local ACRP chapters also gives you a real edge.
Which companies hire senior clinical data managers in St. Louis?
Employers hiring senior clinical data managers in St. Louis right now include Esri, Edward Jones, and Stellar Solutions, based on current listings on Migrate Mate as of July 2026. The St. Louis market is anchored by contract research organizations, academic medical centers, and mid-size biopharma companies with active clinical development pipelines.
Are there remote senior clinical data manager jobs in St. Louis?
Yes, senior clinical data management is one of the more remote-compatible roles in clinical research given its analytical and system-based nature. About 79% of senior clinical data manager openings tied to St. Louis are remote or hybrid as of July 2026, reflecting broader industry trends toward distributed data teams. Database design, data review, and vendor oversight tasks are the most commonly performed remotely, while site-coordination and sponsor-facing work typically requires some in-person presence.
How can I get a senior clinical data manager job in St. Louis with little or no experience?
The most realistic entry path in St. Louis is starting as a clinical data coordinator or data specialist at one of the city's contract research organizations or academic medical centers, such as those affiliated with Washington University or SSM Health's research programs. Building proficiency in Medidata Rave or Oracle Clinical and earning a CCDM certification through SCDM strengthens your case considerably. From there, taking on study lead responsibilities on smaller trials is the typical step toward a senior title locally.
Which industries hire the most senior clinical data managers in St. Louis?
The sectors hiring the most senior clinical data managers in St. Louis are Technology & Software, Consulting & Professional Services, and Education, based on current listings on Migrate Mate as of July 2026. St. Louis's deep base of academic medical research, contract research organizations, and a growing biopharma corridor in the Cortex district drives consistent local demand for experienced data management professionals.
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