Mid Level Senior Clinical Informatics Specialist Jobs

Mid level senior clinical informatics specialist jobs go to professionals ready to own clinical system implementations end to end, lead workflow optimization projects, and guide junior analysts without waiting for direction. Roles are concentrated across Healthcare & Medical Services, Technology & Software, and Education, with a strong mix of remote and hybrid settings, and employers like Cone Health, Novant Health, and Optum hiring at this level now.

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Overview

Open roles20
Top stateNorth Carolina
Top employerCone Health
Top cityGreensboro, NC
Work type54% On-site
Top industryHealthcare

Showing 5 of 20+ Mid Level Senior Clinical Informatics Specialist jobs

Optum
Medical Director Clinical Informatics - Remote
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Optum
Added 5d ago
Medical Director Clinical Informatics - Remote
Optum
Minneapolis, Minnesota
Business Operations
Business Strategy
Consulting & Professional Services
$218k - $373k/yr
Hybrid
Bachelor of Medicine Bachelor of Surgery
10,000+

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University of California - San Francisco
Clinical Informatics Supervisor II
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University of California - San Francisco
Added 5d ago
Clinical Informatics Supervisor II
University of California - San Francisco
California
Data Analytics
Data Science
Healthcare Administration
$150k - $160k/yr
Bachelor's degree in information technology
10,000+

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Novant Health
Clinical Informatics Analyst
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Novant Health
Added 1w ago
Clinical Informatics Analyst
Novant Health
Hilton Head, South Carolina
Business Operations
Program Management
Project Management
Bachelor's degree
10,000+

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Novant Health
Clinical Informatics Analyst
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Novant Health
Added 1w ago
Clinical Informatics Analyst
Novant Health
Wilmington, North Carolina
Account Management
Customer Success
Sales
Bachelor's degree
10,000+

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Children's National Hospital
Clinical Informatics Architect
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Children's National Hospital
Added 3w ago
Clinical Informatics Architect
Children's National Hospital
Silver Spring, Maryland
Healthcare Administration
Clinical Support
Public Health & Informatics
Project & Program Management
Health Informatics
$104k - $173k/yr
On-Site
Bachelor's
5,001-10,000

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Mid Level Senior Clinical Informatics Specialist Job Market

Who's Hiring

Cone Health
Cone Health3 open roles
Novant Health
Novant Health2 open roles
Optum
Optum1 open role

Top Industries Hiring

  • Healthcare & Medical Services15
  • Technology & Software2
  • Education1
  • Insurance1
  • Non-Profit & Social Services1

Mid Level Senior Clinical Informatics Specialist Jobs: Frequently Asked Questions

How do I get a mid level senior clinical informatics specialist job?

Position your experience around ownership rather than participation. Hiring managers at this level want to see that you have led a clinical system build-out, driven an EHR optimization initiative, or served as the primary point of contact between clinical staff and IT. Highlight measurable outcomes, name the platforms you have configured, and show that your decisions improved workflows without requiring constant escalation.

Which companies hire mid level senior clinical informatics specialists?

Companies hiring mid level senior clinical informatics specialists right now include Cone Health, Novant Health, and Optum, based on current listings on Migrate Mate as of September 2026. Hiring at this level comes primarily from health systems, academic medical centers, and large managed care organizations that need specialists who can operate independently across clinical and technical teams.

Are there remote mid level senior clinical informatics specialist jobs?

Yes, though availability varies by employer and project phase. About 46% of mid level senior clinical informatics specialist openings are remote or hybrid as of September 2026, reflecting health systems' growing comfort with distributed informatics teams for roles that do not require hands-on bedside presence. Implementation-heavy roles may still require periodic on-site work during go-live periods.

How do I move up to a mid level senior clinical informatics specialist role?

The path into mid level requires building depth beyond basic EHR support. Focus on taking ownership of a full project cycle, whether a module build, a clinical decision support tool, or a data quality initiative. Demonstrating that you can translate clinical needs into technical requirements, measure your own outcomes, and train others signals the independence that separates mid level candidates from junior ones.

Which industries hire the most mid level senior clinical informatics specialists?

Mid Level senior clinical informatics specialist roles concentrate in Healthcare & Medical Services, Technology & Software, and Education, based on current listings on Migrate Mate as of September 2026. These sectors drive the most hiring because they operate large, complex clinical environments where optimizing EHR workflows and clinical data systems at scale requires experienced specialists who can work with minimal supervision.