Senior Clinical Project Manager Jobs in Kansas City, MO
Senior Clinical Project Manager jobs in Kansas City are concentrated across the healthcare, pharmaceuticals, and medical devices sectors, with demand centered in the Country Club Plaza medical corridor, the Westport health hub, and the growing Waddell & Reed Financial Center district. Employers actively hiring include University Health KC, University of Kansas Medical Center, and Kansas City National Security Campus. See the openings below and apply to the ones that match your experience.
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Showing 5 of 225+ Senior Clinical Project Manager jobs











- Strong SME knowledge in Healthcare Claims Processing lifecycle
- Expertise in EDI formats – 837 (P/I/D), 835, 834
- Hands-on experience in Facets (Claims + Enrollment modules)
- Proficiency in Azure DevOps (ADO) for QA tracking
- Knowledge of HIPAA compliance and payer systems
- 8+ years of experience in Healthcare QA/Testing
- 4+ years of experience as Test Lead in Facets projects
- Deep understanding of Claims Adjudication & Payment workflows
- Experience in handling claims denials, adjustments, and reprocessing
- Strong exposure to EDI claim and remittance transactions
- Experience in mocking and validating EDI files (837/835/834)
- Knowledge of ITS claims processing (SF, DF, RF)
- Experience in Member Enrollment workflows (Medicaid, Medicare, ACA)
- Understanding of Billing lifecycle for member enrollment
- Hands-on experience with ADO Test Plans, Test Suites, and Defect tracking
- Ability to perform data validation and reconciliation activities
- Strong experience in functional and end-to-end testing
- Familiarity with Agile/Scrum methodologies
- Excellent stakeholder communication and coordination skills
- Experience in risk identification, defect triage, and RCA
- Lead end-to-end testing for Claims, Enrollment, and Billing modules
- Act as SME for Claims Processing and EDI transactions
- Validate Facets Claims and Membership workflows
- Design and execute test strategies, test plans, and test cases
- Perform EDI validation (837, 835, 834) including mock data creation
- Manage defect lifecycle, triage, and resolution tracking in ADO
- Ensure HIPAA compliance in all testing activities
- Validate ITS claims processing across SF, DF, RF flows
- Drive quality metrics, reporting, and release sign-offs
- Collaborate with business, development, and partner teams for E2E validation
- Leading and Mentoring team members
- Strong problem-solving and critical thinking
- Ability to work with minimal supervision
- Documentation and knowledge sharing
- Excellent communication
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Find JobsSenior Clinical Project Manager Job Market in Kansas City
Who's Hiring
- University Health KC22

- University of Kansas Medical Center18

- Kansas City National Security Campus17

- Research Medical Center14

- Children's Mercy Hospitals & Clinics13

Top Industries Hiring
- Healthcare & Medical Services53
- Education11
- Consulting & Professional Services9
- Construction & Real Estate8
- Technology & Software5
Senior Clinical Project Manager Jobs in Kansas City: Frequently Asked Questions
How do I get a senior clinical project manager job in Kansas City?
The strongest path into a senior clinical project manager role in Kansas City is through the city's dense concentration of health systems, CROs, and pharmaceutical employers anchored in the Plaza medical corridor and surrounding Midtown districts. Candidates who bring hands-on clinical trial oversight experience, familiarity with ICH-GCP guidelines, and a history managing cross-functional teams stand out most. Building relationships through Kansas City's local healthcare networking events and targeting regional CRO offices gives you a meaningful edge over remote applicants.
Which companies hire senior clinical project managers in Kansas City?
Companies currently hiring senior clinical project managers in Kansas City include University Health KC, University of Kansas Medical Center, and Kansas City National Security Campus, per current listings on Migrate Mate as of July 2026. Kansas City's hiring base skews toward regional health systems, contract research organizations with Midwest operations, and pharmaceutical companies that have established clinical operations hubs in the metro area.
Are there remote senior clinical project manager jobs in Kansas City?
Yes, though with limits, since senior clinical project managers often need to coordinate on-site monitoring visits and investigator meetings that require periodic in-person presence. About 36% of senior clinical project manager openings tied to Kansas City are remote or hybrid as of July 2026, with availability varying by employer type. Fully remote arrangements are most common for project planning, vendor management, and regulatory documentation tasks rather than site-facing responsibilities.
How can I get a senior clinical project manager job in Kansas City with little or no experience?
The most realistic entry path in Kansas City is starting as a clinical research associate or clinical trial coordinator at one of the metro's regional health systems or CRO satellite offices, then building toward a senior PM role through demonstrated trial lifecycle ownership. Employers in the Westport and Plaza corridors frequently promote from within, so joining in a coordinator capacity and volunteering for cross-functional project work positions you for advancement without requiring a national job search.
Which industries hire the most senior clinical project managers in Kansas City?
The sectors hiring the most senior clinical project managers in Kansas City are Healthcare & Medical Services, Education, and Consulting & Professional Services, based on current listings on Migrate Mate as of July 2026. Kansas City's status as a regional healthcare hub, combined with a growing pharmaceutical and medical device presence along the I-35 corridor, keeps consistent demand for experienced clinical project managers across all three of those sectors.
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