Senior Clinical Project Manager Jobs in St. Louis, MO
Senior Clinical Project Manager jobs in St. Louis are in steady demand, concentrated in the Cortex Innovation Community, Midtown Medical District, and the Research Park near Washington University, across pharmaceutical development, medical device companies, and health system clinical operations. Employers hiring right now include BJC HealthCare, Washington University in St. Louis, and SSM Health. Find a role that fits below and apply directly.
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Showing 5 of 473+ Senior Clinical Project Manager jobs
Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact.
A Day in the Life
We are seeking a committed professional to join our team, required to reside within the territory and drive to multiple accounts throughout the region. A valid driver's license is essential for this role, which also includes travel outside the territory, presenting opportunities for broader engagement.As one of three comprehensive portfolios at Medtronic, Neuroscience is dedicated to improving the lives of people living with neurological disorders, spine conditions, and chronic pain. Guided by our Mission—to alleviate pain, restore health, and extend life—we develop technologies and therapies that help people regain function, reduce pain, and return to the activities that matter most.
Our Neuromodulation Operating Unit provides advanced therapies for chronic pain, movement disorders, and other neurological conditions. Through therapies such as spinal cord stimulation and targeted drug delivery systems, we deliver personalized treatments that restore function, reduce symptoms, and improve quality of life worldwide.
Check us out on LinkedIn: Pain Interventions
At Medtronic, the Clinical Specialist, supports the Neuromodulation Pain and Target Drug Delivery Therapies in the areas of surgical coverage, follow-up support, troubleshooting, customer service and education. This person will be engaged in basic market development activities depending upon the needs of the assigned territory and district.
This is a field based role.
Responsibilities may include the following and other duties may be assigned:
Represents Medtronic as device specialist during surgical procedures by ensuring all necessary equipment and products required are available, providing technical support and device selection, and performing programming and testing of all device systems
Manages patients through all phases of the clinical process as well as educate them on the features and benefits of Medtronic products
Provides clinical support in surgeries, re-programmings , trouble-shooting and follow ups in hospitals and clinics
Educates and trains physicians, hospital personnel and office staff on products and therapies. This is expected by, but not limited to, coordinating one on one teaching sessions, formal in-services, education programs, seminars and/or outside symposia (based off quarterly Plan of Action as directed by Leadership)
Responds promptly and professionally to device-related inquiries by customers and patients
Ability to be flexible with schedule while working and/or attending clinical events, possibly outside of normal business hours to include weekends and after hours and at the discretion of Clinical Specialist Manager
Adheres to company policies and complies with required event reporting and documentation, utilizing Medtronic technology tools
Responsible for managing inventory provided for case coverage, including: timely transactions when product is used, sold or transferred, maintaining a required level of cycle count accuracy, executing product retrievals as instructed, turning over inventory in a reasonable time frame , not implanting expired product or product that is on hold
Contributes to the achievement of quarterly goals associated with specific initiatives at the district, regional and/or national level by partnering with colleagues and communicating effectively and regularly with Leadership
Maintains a working knowledge of competitive products
Regularly visits accounts to establish /maintain relationships with office staff and Health care providers
Accountable for placing orders with customer service for pending purchase orders and product replacement
Expected to work with materials management to collect POs for cases covered within the territory/district
Ensures personal understanding of all quality policies/system items that are personally applicable
Assists Management and Sales Training department in education/training of new employees within the district
Effectively utilizes Excel, a mobile phone, an IPAD, a laptop, and/or a Samsung tablet regularly
Manages business expenses and budget effectively and in given timeframe
Mentors Associate Clinical Specialists
Completes all new hire therapy trainings as directed by medical education
Completes all corporate compliance training prior to date due
Travels to cover district cases as needed in the district, and occasionally to other districts at the discretion of Clinical Manager
We are committed to building a workforce that brings together a broad range of perspectives and experiences at every level. This approach fuels innovation and helps us remain an industry leader— that’s why we focus on attracting and developing employees who are patient-centric, passionate, and deeply connected to the needs of the patients we serve.
To learn more about Inclusion & Diversity at Medtronic, click here .
Qualifications
Must Have: Minimum Requirements
To be considered for this role, please ensure these minimum requirements are evident in your applicant profile.
A High School Diploma or GED with a minimum of 6 years of clinical or medical sales experience; or
An Associate's degree with a minimum of 4 years of clinical or medical sales experience; or
A Bachelor’s degree with a minimum of 2 years of clinical or medical sales experience.
Nice to Have
Bachelor's degree in a health care related field
Master’s degree
Registered nurse or HCP with experience in a sterile environment
Clinical experience with implantable neurological products and patient care
Experience in servicing medical personnel on product use
Experience with a medical device company or pharmaceutical company, and clinical experience in a specialty area: neurology, neurosurgery, orthopedic , operating room, pain management, or home health care
Understands basic reimbursement and healthcare environment
Excellent organizational skills and ability to work under pressure
Other Job Requirements
Required to function using healthcare universal precautions to minimize exposure to infectious disease and radiation
Ability to serve as the primary resource for scheduled and unscheduled clinical events, periodically required to work weekends, evenings and nights and may be required to engage in overnight travel within own district or neighboring districts
Ability to work efficiently and autonomously with little direction when outside of clinical events
Ability to attend national meetings, district meetings and other training as requested
Ability to wear a 7-9 lbs protective lead apron for extended periods of time in the operating room
Ability to lift up to 40 lbs
Ability to sitting, standing, and/or walking for 8+ hours per day
Ability to bend/stoop, squat and balance frequently
Specific vision abilities required by this job include close vision, distance vision, depth perception, and ability to adjust focus in relation to travel and operating a personal computer.
Must have a valid driver's license and active vehicle insurance policy. In addition, your driving record will be reviewed and will be considered as part of your application. Must be able to drive approximately 50% of the time within assigned territory and may require overnight travel.
For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required.
Physical Job Requirements
The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.
The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.
U.S. Work Authorization & Sponsorship
At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment.
Recruitment Fraud Alert
We are aware of phishing scams targeting job seekers. Please keep the following in mind:
Apply only through official Medtronic channels. All legitimate Medtronic recruiting communications come from approved Medtronic platforms and official @medtronic.com email addresses.
Medtronic will never ask for payment or sensitive personal information (such as bank account or Social Security details) during early stages of the hiring process. Any such requests are not legitimate.
If you receive a suspicious message claiming to be from Medtronic, do not respond, click links, or open attachments.
If you have any questions, concerns regarding the authenticity of a communication alleged to have been made by or on behalf of Medtronic, please contact us immediately at AskHR@medtronic.com .
Benefits & Compensation
Medtronic offers a competitive Salary and flexible Benefits Package
A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create. We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage.
The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others).
In addition to Base Salary, this position is eligible for a Sales Incentive Plan (SIP), which provides the opportunity to earn significant incentive compensation for achieving or exceeding your goals.
The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance , Health Savings Account , Healthcare Flexible Spending Account , Life insurance, Long-term disability leave , Dependent daycare spending account , Tuition assistance/reimbursement , and Simple Steps (global well-being program).
The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match , Short-term disability , Paid time off , Paid holidays , Employee Stock Purchase Plan , Employee Assistance Program , Non-qualified Retirement Plan Supplement (subject to IRS earning minimums) , and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums).
Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico.
Further details are available at the link below:
Medtronic benefits and compensation plans
It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities.
If you are applying to perform work for Medtronic, Inc. (“Medtronic”) in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact.
A Day in the Life
We are seeking a committed professional to join our team, required to reside within the territory and drive to multiple accounts throughout the region. A valid driver's license is essential for this role, which also includes travel outside the territory, presenting opportunities for broader engagement.As one of three comprehensive portfolios at Medtronic, Neuroscience is dedicated to improving the lives of people living with neurological disorders, spine conditions, and chronic pain. Guided by our Mission—to alleviate pain, restore health, and extend life—we develop technologies and therapies that help people regain function, reduce pain, and return to the activities that matter most.
Our Neuromodulation Operating Unit provides advanced therapies for chronic pain, movement disorders, and other neurological conditions. Through therapies such as spinal cord stimulation and targeted drug delivery systems, we deliver personalized treatments that restore function, reduce symptoms, and improve quality of life worldwide.
Check us out on LinkedIn: Pain Interventions
At Medtronic, the Clinical Specialist, supports the Neuromodulation Pain and Target Drug Delivery Therapies in the areas of surgical coverage, follow-up support, troubleshooting, customer service and education. This person will be engaged in basic market development activities depending upon the needs of the assigned territory and district.
This is a field based role.
Responsibilities may include the following and other duties may be assigned:
Represents Medtronic as device specialist during surgical procedures by ensuring all necessary equipment and products required are available, providing technical support and device selection, and performing programming and testing of all device systems
Manages patients through all phases of the clinical process as well as educate them on the features and benefits of Medtronic products
Provides clinical support in surgeries, re-programmings , trouble-shooting and follow ups in hospitals and clinics
Educates and trains physicians, hospital personnel and office staff on products and therapies. This is expected by, but not limited to, coordinating one on one teaching sessions, formal in-services, education programs, seminars and/or outside symposia (based off quarterly Plan of Action as directed by Leadership)
Responds promptly and professionally to device-related inquiries by customers and patients
Ability to be flexible with schedule while working and/or attending clinical events, possibly outside of normal business hours to include weekends and after hours and at the discretion of Clinical Specialist Manager
Adheres to company policies and complies with required event reporting and documentation, utilizing Medtronic technology tools
Responsible for managing inventory provided for case coverage, including: timely transactions when product is used, sold or transferred, maintaining a required level of cycle count accuracy, executing product retrievals as instructed, turning over inventory in a reasonable time frame , not implanting expired product or product that is on hold
Contributes to the achievement of quarterly goals associated with specific initiatives at the district, regional and/or national level by partnering with colleagues and communicating effectively and regularly with Leadership
Maintains a working knowledge of competitive products
Regularly visits accounts to establish /maintain relationships with office staff and Health care providers
Accountable for placing orders with customer service for pending purchase orders and product replacement
Expected to work with materials management to collect POs for cases covered within the territory/district
Ensures personal understanding of all quality policies/system items that are personally applicable
Assists Management and Sales Training department in education/training of new employees within the district
Effectively utilizes Excel, a mobile phone, an IPAD, a laptop, and/or a Samsung tablet regularly
Manages business expenses and budget effectively and in given timeframe
Mentors Associate Clinical Specialists
Completes all new hire therapy trainings as directed by medical education
Completes all corporate compliance training prior to date due
Travels to cover district cases as needed in the district, and occasionally to other districts at the discretion of Clinical Manager
We are committed to building a workforce that brings together a broad range of perspectives and experiences at every level. This approach fuels innovation and helps us remain an industry leader— that’s why we focus on attracting and developing employees who are patient-centric, passionate, and deeply connected to the needs of the patients we serve.
To learn more about Inclusion & Diversity at Medtronic, click here .
Qualifications
Must Have: Minimum Requirements
To be considered for this role, please ensure these minimum requirements are evident in your applicant profile.
A High School Diploma or GED with a minimum of 6 years of clinical or medical sales experience; or
An Associate's degree with a minimum of 4 years of clinical or medical sales experience; or
A Bachelor’s degree with a minimum of 2 years of clinical or medical sales experience.
Nice to Have
Bachelor's degree in a health care related field
Master’s degree
Registered nurse or HCP with experience in a sterile environment
Clinical experience with implantable neurological products and patient care
Experience in servicing medical personnel on product use
Experience with a medical device company or pharmaceutical company, and clinical experience in a specialty area: neurology, neurosurgery, orthopedic , operating room, pain management, or home health care
Understands basic reimbursement and healthcare environment
Excellent organizational skills and ability to work under pressure
Other Job Requirements
Required to function using healthcare universal precautions to minimize exposure to infectious disease and radiation
Ability to serve as the primary resource for scheduled and unscheduled clinical events, periodically required to work weekends, evenings and nights and may be required to engage in overnight travel within own district or neighboring districts
Ability to work efficiently and autonomously with little direction when outside of clinical events
Ability to attend national meetings, district meetings and other training as requested
Ability to wear a 7-9 lbs protective lead apron for extended periods of time in the operating room
Ability to lift up to 40 lbs
Ability to sitting, standing, and/or walking for 8+ hours per day
Ability to bend/stoop, squat and balance frequently
Specific vision abilities required by this job include close vision, distance vision, depth perception, and ability to adjust focus in relation to travel and operating a personal computer.
Must have a valid driver's license and active vehicle insurance policy. In addition, your driving record will be reviewed and will be considered as part of your application. Must be able to drive approximately 50% of the time within assigned territory and may require overnight travel.
For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required.
Physical Job Requirements
The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.
The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.
U.S. Work Authorization & Sponsorship
At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment.
Recruitment Fraud Alert
We are aware of phishing scams targeting job seekers. Please keep the following in mind:
Apply only through official Medtronic channels. All legitimate Medtronic recruiting communications come from approved Medtronic platforms and official @medtronic.com email addresses.
Medtronic will never ask for payment or sensitive personal information (such as bank account or Social Security details) during early stages of the hiring process. Any such requests are not legitimate.
If you receive a suspicious message claiming to be from Medtronic, do not respond, click links, or open attachments.
If you have any questions, concerns regarding the authenticity of a communication alleged to have been made by or on behalf of Medtronic, please contact us immediately at AskHR@medtronic.com .
Benefits & Compensation
Medtronic offers a competitive Salary and flexible Benefits Package
A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create. We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage.
The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others).
In addition to Base Salary, this position is eligible for a Sales Incentive Plan (SIP), which provides the opportunity to earn significant incentive compensation for achieving or exceeding your goals.
The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance , Health Savings Account , Healthcare Flexible Spending Account , Life insurance, Long-term disability leave , Dependent daycare spending account , Tuition assistance/reimbursement , and Simple Steps (global well-being program).
The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match , Short-term disability , Paid time off , Paid holidays , Employee Stock Purchase Plan , Employee Assistance Program , Non-qualified Retirement Plan Supplement (subject to IRS earning minimums) , and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums).
Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico.
Further details are available at the link below:
Medtronic benefits and compensation plans
It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities.
If you are applying to perform work for Medtronic, Inc. (“Medtronic”) in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
See All 473+ Senior Clinical Project Manager Jobs in St. Louis
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Find JobsSenior Clinical Project Manager Job Market in St. Louis
Who's Hiring
- BJC HealthCare153
- Washington University in St. Louis57
- SSM Health42
- Mercy14
- State of Missouri8
Top Industries Hiring
- Healthcare & Medical Services55
- Education45
- Consulting & Professional Services17
- Technology & Software13
- Construction & Real Estate11
Senior Clinical Project Manager Jobs in St. Louis: Frequently Asked Questions
How do I get a senior clinical project manager job in St. Louis?
The strongest path in St. Louis is targeting the city's three main hiring pockets: health systems and academic medical centers in the Midtown corridor, pharmaceutical and biotech firms in the Cortex Innovation Community, and contract research organizations serving both. Candidates with end-to-end clinical trial experience, a PMP or CAPM credential, and familiarity with FDA submission timelines stand out in this market. Networking through BJC HealthCare, SSM Health, or Mallinckrodt-affiliated research programs also opens doors that job boards alone won't.
Which companies hire senior clinical project managers in St. Louis?
Employers hiring senior clinical project managers in St. Louis right now include BJC HealthCare, Washington University in St. Louis, and SSM Health, based on current listings on Migrate Mate as of July 2026. St. Louis draws a mix of large integrated health systems, mid-size pharmaceutical manufacturers, and CROs with regional offices anchored near the Cortex and Forest Park Southeast corridors.
Are there remote senior clinical project manager jobs in St. Louis?
Yes, though with limits: senior clinical project manager work is partly remote-friendly for protocol development, vendor oversight, and reporting, but site visits and sponsor meetings often require in-person presence. About 53% of senior clinical project manager openings tied to St. Louis are remote or hybrid as of July 2026, with the fully remote share skewed toward CRO roles rather than hospital-based positions. Regulatory and data-management functions in St. Louis tend to offer the most scheduling flexibility.
How can I get a senior clinical project manager job in St. Louis with little or no experience?
The most realistic entry point in St. Louis is a clinical research coordinator or associate project manager role at one of the city's academic medical centers, such as those affiliated with Washington University School of Medicine or Saint Louis University's clinical research programs. From there, moving into a senior CPM title typically takes three to five years of direct trial management experience. Local CROs and Pfizer's regional offices also recruit coordinators who can grow into project leadership with demonstrated protocol oversight skills.
Which industries hire the most senior clinical project managers in St. Louis?
Most senior clinical project manager openings in St. Louis sit in Healthcare & Medical Services, Education, and Consulting & Professional Services, per current listings on Migrate Mate as of July 2026. St. Louis has a long-established pharmaceutical manufacturing heritage and a growing biotech cluster in Cortex, which together sustain consistent demand for experienced clinical operations leadership across both early-phase and late-phase trials.
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