Senior Python Engineer Jobs

Senior Python Engineer jobs are open across fintech, healthtech, enterprise software, and cloud infrastructure, from mid-level to staff and principal, with specializations in data engineering, backend systems, and machine learning pipelines. Find a role that fits from the openings below and apply directly.

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Overview

Open roles32+
Top stateNew York
Top employerCiti
Top cityCharlotte, NC
Work type72% On-site
Top industryTechnology

Showing 5 of 32+ Senior Python Engineer jobs

Grid Dynamics
Senior Python Engineer
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Grid Dynamics
Added 1mo ago
Senior Python Engineer
Grid Dynamics
United States
Software Engineering
Data Science & Analytics
Data Engineering
Cloud & DevOps
Data Science
On-Site
Bachelor's

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Comcast
Senior Python Engineer
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Comcast
Added 1mo ago
Senior Python Engineer
Comcast
Washington, Washington DC
Software Engineering
Technical Product & Program Management
Backend Engineering
AI (Artificial Intelligence)
Technical Program Management
$168k - $252k/yr
On-Site
Bachelor's
10,000+

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Citi
Senior Python Engineer
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Citi
Added 2mo ago
Senior Python Engineer
Citi
New York, New York
Software Engineering
Data Science & Analytics
Technical Product & Program Management
Backend Engineering
$121k - $182k/yr
On-Site
None
10,000+

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Mancini Law Group P.C.
Sr. Python Engineer, Agentic AI
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Mancini Law Group P.C.
Added 1mo ago
Sr. Python Engineer, Agentic AI
Mancini Law Group P.C.
Washington, Washington DC
Software Engineering
Technical Product & Program Management
Backend Engineering
AI (Artificial Intelligence)
Technical Program Management
Hybrid
Bachelor's

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AHU Technologies
Senior Python Backend Engineer
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AHU Technologies
Added 1mo ago
Senior Python Backend Engineer
AHU Technologies
Washington, Washington DC
Software Engineering
Backend Engineering
On-Site
None

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Senior Python Engineer Job Market

A snapshot from current openings nationwide, updated as new roles post.

Who's Hiring

  • Citi
    Citi6
  • Synechron
    Synechron5
  • Luxoft
    Luxoft2
  • AHU Technologies
    AHU Technologies1
  • AIAEC
    AIAEC1

Top Industries Hiring

  • Technology & Software20
  • Banking & Financial Services5
  • Agriculture & Farming2
  • Consulting & Professional Services2
  • Investment & Asset Management2

What Employers Look For

The qualifications that appear most often in senior python engineer jobs.

  • Five or more years of professional Python development experience
  • Deep knowledge of at least one major web or API framework such as FastAPI or Django
  • Experience designing and maintaining distributed or microservices-based systems
  • Proficiency with SQL and at least one cloud platform such as AWS, GCP, or Azure
  • Demonstrated ability to mentor junior engineers and lead code reviews
  • Familiarity with containerization and orchestration tools including Docker and Kubernetes

Tips for Your Senior Python Engineer Job Search

Tailor your resume to each stack

Senior Python Engineer roles vary widely by infrastructure, so list the specific frameworks and tools each job mentions, whether that's FastAPI, Django, Celery, or Airflow, rather than a single generic skills block that covers everything.

Show system design decisions you owned

Hiring managers at the senior level want evidence you drove architecture, not just implemented tickets. For each project on your resume, name the design choice you made and the measurable outcome it produced.

Filter openings by domain, not just title

A senior python engineer role at a fintech firm often demands different depth than one at a data platform company. Narrow your search by industry vertical so your cover note can speak directly to the domain's specific constraints.

Apply early to roles that fit

Migrate Mate lists senior python engineer openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Prepare a live coding environment in advance

Many senior python engineer technical rounds use a shared editor or ask you to run code locally. Have your preferred IDE configured, linting enabled, and a few recent personal projects open before your first screen.

Negotiate scope before negotiating anything else

At the senior level, the technical charter matters as much as the offer. Before your final conversation, ask specifically what the first major project is, who owns the roadmap, and whether the role includes cross-team design review responsibilities.

Senior Python Engineer Jobs: Frequently Asked Questions

Which companies are hiring the most senior python engineers?

The companies hiring the most senior python engineers right now include Citi, Synechron, and Luxoft, with the largest share of openings in New York, North Carolina, and Pennsylvania, based on current listings on Migrate Mate as of June 2026. Demand is concentrated in fintech, cloud infrastructure, and enterprise data platform companies.

How many senior python engineer jobs are remote?

About 28% of senior python engineer openings are fully remote or hybrid as of June 2026, making it one of the more remote-accessible senior engineering roles. Backend API and data engineering specializations tend to carry the highest share of fully remote listings compared to roles requiring on-site infrastructure work.

How do you become a senior python engineer?

You become a senior python engineer by building deep, demonstrable expertise in Python's ecosystem and taking ownership of system-level decisions. Start by shipping production services end-to-end, then move into roles where you design architecture rather than implement specs. Consistently mentoring other engineers and leading technical reviews accelerates the transition more reliably than accumulating years alone.

Can you get hired as a senior python engineer with little experience?

Getting hired as a senior python engineer with limited professional experience is difficult through conventional applications, but candidates have succeeded by demonstrating senior-level judgment through open-source contributions, public architecture write-ups, or a well-documented side project that solved a real scalability problem. Targeting smaller companies or early-stage startups that weight portfolio evidence over years on a resume also improves the odds.

What does the senior python engineer interview process look like?

The senior python engineer interview process typically moves through a recruiter screen, a technical phone screen focused on Python internals and system design concepts, a live coding round using a shared editor, and a final system design interview where you architect a service under real constraints. Many companies add a hiring manager conversation to assess how you approach cross-team collaboration and technical leadership.

Where can I find and apply to senior python engineer jobs?

You can find and apply to senior python engineer jobs on Migrate Mate, which lists current openings from across the United States. Search the listings to find roles that match your background and apply directly to each one that fits.

See All 32+ Senior Python Engineer Jobs

Jump back to the full list of openings and apply to any senior python engineer role that fits.

Find Senior Python Engineer Jobs