Senior Software Developer Jobs in Cambridge, MA
Senior Software Developer jobs in Cambridge, Massachusetts are concentrated in Kendall Square, East Cambridge, and the Alewife corridor, with strong demand from biotech, life sciences, and enterprise software employers. Akamai Technologies, Google, and Nanobiosym are among the companies posting roles right now. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 134+ Senior Software Developer jobs
Your Impact at LILA
You will steward Verification & Validation and software quality for our autonomous labs, where software meets real robotics hardware. On the Independent Verification & Validation team, you'll build the V&V, Hardware-in-the-Loop, and UI testing that lets us ship fast without breaking the lab, partnering with platform, simulation, and human-factors engineers to catch failures in test rather than on the bench.
What You'll Be Building
- Automate the test suites: fast, reliable Python automation — from pytest unit and API coverage to Playwright UI flows — wired into CI/CD (GitHub Actions).
- Validate against hardware: Hardware-in-the-Loop tests that exercise platform software against real and simulated robotics hardware, integrated with our simulation and digital-twin systems.
- Own V&V and test planning: verification & validation processes and test plans that map requirements to coverage across the software-to-hardware boundary.
- Test the interfaces scientists use: UI testing for the internal dashboards and orchestration UIs that drive the factory.
- Tame nondeterminism: regression and reliability testing that isolates flakiness and keeps signal high as the platform grows.
- Manage test data: fixtures that make results reproducible and failures diagnosable.
What You'll Need to Succeed
- Test/QA automation depth: 4–8 years in software test or QA automation for complex, integrated systems.
- Automation in Python: hands-on with pytest and a modern UI framework (Playwright); front-end unit testing (Vitest/Jest) a plus.
- V&V and test strategy: defining test plans and V&V processes, and reasoning about what to test at which layer.
- CI/CD integration: embedding tests into pipelines (GitHub Actions or similar) and keeping them fast and stable.
- Integration & HIL mindset: testing across service, UI, and hardware boundaries, including nondeterministic behavior.
- Cross-functional communication: working alongside platform and simulation engineers and communicating risk clearly.
Bonus Points For
- Hardware-in-the-Loop experience: prior HIL, robotics, or lab automation testing against physical or simulated devices.
- Simulation / digital twin: testing software against simulators or digital-twin environments.
- Test infrastructure: building test data management, fixtures, or reporting for large suites.
- Systems engineering & regulated industries: V&V experience in aerospace, manufacturing, or healthcare/life sciences, and a systems-thinking approach to the software-hardware boundary. Exposure to GAMP 5 / FDA CSA, 21 CFR Part 11, or DO-178C a plus.
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We're All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
Your Impact at LILA
You will steward Verification & Validation and software quality for our autonomous labs, where software meets real robotics hardware. On the Independent Verification & Validation team, you'll build the V&V, Hardware-in-the-Loop, and UI testing that lets us ship fast without breaking the lab, partnering with platform, simulation, and human-factors engineers to catch failures in test rather than on the bench.
What You'll Be Building
- Automate the test suites: fast, reliable Python automation — from pytest unit and API coverage to Playwright UI flows — wired into CI/CD (GitHub Actions).
- Validate against hardware: Hardware-in-the-Loop tests that exercise platform software against real and simulated robotics hardware, integrated with our simulation and digital-twin systems.
- Own V&V and test planning: verification & validation processes and test plans that map requirements to coverage across the software-to-hardware boundary.
- Test the interfaces scientists use: UI testing for the internal dashboards and orchestration UIs that drive the factory.
- Tame nondeterminism: regression and reliability testing that isolates flakiness and keeps signal high as the platform grows.
- Manage test data: fixtures that make results reproducible and failures diagnosable.
What You'll Need to Succeed
- Test/QA automation depth: 4–8 years in software test or QA automation for complex, integrated systems.
- Automation in Python: hands-on with pytest and a modern UI framework (Playwright); front-end unit testing (Vitest/Jest) a plus.
- V&V and test strategy: defining test plans and V&V processes, and reasoning about what to test at which layer.
- CI/CD integration: embedding tests into pipelines (GitHub Actions or similar) and keeping them fast and stable.
- Integration & HIL mindset: testing across service, UI, and hardware boundaries, including nondeterministic behavior.
- Cross-functional communication: working alongside platform and simulation engineers and communicating risk clearly.
Bonus Points For
- Hardware-in-the-Loop experience: prior HIL, robotics, or lab automation testing against physical or simulated devices.
- Simulation / digital twin: testing software against simulators or digital-twin environments.
- Test infrastructure: building test data management, fixtures, or reporting for large suites.
- Systems engineering & regulated industries: V&V experience in aerospace, manufacturing, or healthcare/life sciences, and a systems-thinking approach to the software-hardware boundary. Exposure to GAMP 5 / FDA CSA, 21 CFR Part 11, or DO-178C a plus.
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We're All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
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Find JobsSenior Software Developer Job Market in Cambridge
Who's Hiring
- Akamai Technologies34
- Google22
- Nanobiosym22
- Lila Sciences22
- Raytheon11
Top Industries Hiring
- Technology & Software34
- Education11
- Consulting & Professional Services11
Senior Software Developer Jobs in Cambridge: Frequently Asked Questions
How do I get a senior software developer job in Cambridge?
Target Kendall Square and East Cambridge first, where biotech platforms, academic spinouts, and enterprise software companies cluster most heavily. Candidates with experience in distributed systems, cloud infrastructure, or full-stack development for regulated industries tend to stand out. Engaging with the MIT and Harvard research ecosystem, whether through open-source contributions or technical talks, also builds visibility with the employers and hiring managers most active in Cambridge.
Which companies hire senior software developers in Cambridge?
Cambridge senior software developer roles are posted by Akamai Technologies, Google, and Nanobiosym and others right now, based on current listings on Migrate Mate as of August 2026. Cambridge employers range from global biotech and pharmaceutical firms to early-stage startups spun out of university research labs, giving candidates a wide spectrum of company size and technical focus to choose from.
Are there remote senior software developer jobs in Cambridge?
Yes, and senior software developers are among the more remote-friendly roles given the nature of the work. About 50% of senior software developer openings tied to Cambridge are remote or hybrid as of August 2026, which reflects strong employer flexibility across the tech and biotech sectors. Backend, platform, and data engineering responsibilities in particular are most commonly offered in fully remote or hybrid arrangements by Cambridge employers.
How can I get a senior software developer job in Cambridge with little or no experience?
The most realistic path is targeting junior or mid-level software engineering roles at Cambridge's smaller biotech startups or university-affiliated technology ventures, where teams are lean and developers often grow quickly into senior responsibilities. Contributing to open-source projects connected to MIT CSAIL or Broad Institute research can also build a visible portfolio with local employers. Lateral moves from QA engineering or data engineering roles within Cambridge companies are a common stepping stone as well.
Which industries hire the most senior software developers in Cambridge?
Most senior software developer openings in Cambridge sit in Technology & Software, Education, and Consulting & Professional Services, per current listings on Migrate Mate as of August 2026. Cambridge's density of life sciences companies, academic medical institutions, and enterprise software firms creates sustained demand across those sectors, with technology infrastructure and clinical data platforms driving a significant share of active postings.
Related Jobs in Massachusetts
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