Senior Software Development Engineer Jobs in Wisconsin
Senior Software Development Engineer jobs in Wisconsin are consistently active, with strong demand concentrated in healthcare technology, financial services software, and enterprise systems across Milwaukee, Madison, and the Fox Valley corridor. Major employers with lasting Wisconsin footprints include Epic Systems, Northwestern Mutual, and Fiserv, all of which maintain substantial engineering teams in the state. The most sought-after specialties are cloud-native architecture, distributed systems design, and full-stack platform engineering at scale. Find a role that fits below and apply directly.
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Join the best radiopharmaceutical company in the world!
If you’re looking to make an impact while building a meaningful career in a specialized, fast-growing field, NorthStar Medical Radioisotopes is the place to do it. NorthStar Medical Radioisotopes is a growing, commercial-stage company focused on advancing patient care by providing therapeutic radioisotopes and novel radiopharmaceuticals to detect and treat cancer.
At the forefront of NorthStar’s technological innovation is scientific excellence, using first-in-kind electron accelerator technology and integrated campus capabilities to drive progress in radiopharmaceutical manufacturing. Our work is driven by a meaningful mission—advancing life-saving radiopharmaceutical development and ensuring a reliable supply of critical medical isotopes for patients in need. As a rapidly growing organization operating on the cutting edge of science, we offer exceptional career growth and professional development opportunities, supported by world-class facilities and a competitive benefits package.
Position:This position requires a minimum onsite presence of three days per week at our Beloit, WI location.
Responsibilities:
- Design, develop, and implement AI-enabled applications and tools based on defined requirements - collaborating heavily with Process Excellence, SMEs, End Users, and IT teams.
- Participate in process re-engineering efforts applying systems engineering and lean practices, including kaizen, continuous improvement cycles, risk management, process mapping across domains.
- Translate process and functional requirements into working software solutions with user-friendly interfaces, and scalable structures.
- Plan software structure including data models, APIs, front-end/back-end structures, and AI/LLM integrations.
- Participate in rapid development cycles with other developers in building applications using AI-assisted coding tools.
- Evaluate and implement AI development tools, frameworks, and workflows to improve speed and quality of development. Develop standards for version control, testing and deployment approaches, and documentation practices.
- Test, debug, and validate applications for reliability and performance, supporting validation activities as required.
- Ensure alignment with organizational governance, data strategy, and security expectations.
After 6 months you will:
Bachelor’s degree in a technical field and minimum three (3) years of experience; or equivalent combination of education and experience. Strong experience building full-stack applications, APIs, and AI-enabled solutions for enterprise business systems.
Please note the company cannot provide immigration-related sponsorship (including H-1B status, O-1 status, Optional Practical Training support, etc.) for this position. Each successful applicant will be required to complete the Form I-9, Employment Eligibility Verification, demonstrating both identity and employment authorization, on or before the first day of employment. Under federal law, only truthful information may be provided on the Form I-9.
COMPUTER SKILLS
In addition to familiarity with Microsoft Office software programs, including Outlook, Word, and Excel, ability with the following computer skills:
- Proficiency in Python, JavaScript/TypeScript, and modern development frameworks.
- Familiarity with rapid development using AI-assisted coding tools (e.g., Claude, Codex, GitHub Copilot, similar tools).
- Experience integrating AI/ML models into applications.
- Strong debugging, testing, and code optimization skills.
- Strong understanding of data models, system integration, and application workflows.
- Experience designing and consuming REST APIs.
- Familiarity with system integration across enterprise applications (ERP, CRM, data systems, etc.).
- Knowledge of API security, authentication (OAuth, tokens), and data flows.
- Knowledge of databases (SQL and/or NoSQL).
- Experience with version control systems (Git-based workflows).
- Familiarity with CI/CD pipelines.
- Knowledge of cloud platforms (Azure, AWS, or GCP). Experience deploying and maintaining production applications.
- Experience with unit testing, integration testing, and validation practices.
- Knowledge of application security principles and best practices.
- Understanding of data governance, risk, and compliance considerations. Experience documenting systems and maintaining development standards
- Medical, dental, and vision insurance
- Healthcare Flex Spending Account (FSA) and Dependent Care FSA
- Company-paid short-term and long-term disability
- Company-paid life insurance & AD&D coverage
- Pet insurance
- 401(k) match
- Paid holidays and paid time off (PTO)
- Paid parental leave
- Bonus plan
- Equity Incentive Program
- Exposure to varying temperatures, both indoors (heated/air-conditioned spaces) and outdoors
- Noise levels range from quiet to loud, depending on the work area
- Specific vision abilities, including near vision, visual acuity, and color discrimination
- Respirators, gloves, safety glasses, and full protective clothing
- Compliance with cleanroom gowning protocols (e.g., removal of all jewelry, including piercings)
- Prohibition of cosmetics, fragrances (perfume, aftershave), and nail products, including polish, artificial nails, or extensions
- Follow strict radiation safety procedures
- Participate in dosimetry monitoring and bioassay testing as part of the company protocol
- Inform leadership of any health conditions that may affect product integrity, by cleanroom standards
NorthStar Medical Radioisotopes is proud to call Beloit, Wisconsin home. Our headquarters and primary manufacturing facility are located in this vibrant, growing community that combines the charm of a small city with the advantages of a central Midwest location. Beloit features a lively, revitalized downtown filled with local restaurants, shops, and cultural events, and is just a short drive from major metropolitan areas including Madison, Milwaukee, Chicago, and Rockford.
Situated in the heart of the South Central Wisconsin and Northern Illinois region, Beloit offers a rare blend of urban amenities and scenic natural surroundings. Whether you’re drawn to outdoor recreation, educational institutions, the arts, or historic landmarks, the area provides rich and diverse experiences for all interests. A variety of nearby communities, ranging from rural towns to suburban neighborhoods, offer flexible housing options and access to multiple school districts, making Beloit an excellent choice for individuals and families considering relocation.
Please note that this position is eligible for a lump sum relocation benefit!
NorthStar Medical Radioisotopes is an equal opportunity employer. Employment decisions are made without regard to race, color, religion, national or ethnic origin, sex, sexual orientation, gender identity or expression, age, disability, protected veteran status or other characteristics protected by law.
See All 43 Senior Software Development Engineer Jobs in Wisconsin
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Where Wisconsin roles are concentrated, by current openings.
Senior Software Development Engineer Job Market in Wisconsin
A snapshot from current Wisconsin openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Technology & Software
- Artificial Intelligence
- Manufacturing
- Investment & Asset Management
What Wisconsin Employers Look For
The qualifications that appear most often in senior software development engineer jobs across Wisconsin.
- Bachelor's or master's degree in computer science, software engineering, or a related field
- Seven or more years of professional software development experience in production environments
- Deep proficiency in at least one compiled language such as Java, C++, or C#
- Demonstrated experience designing and maintaining large-scale distributed or cloud-based systems
- Strong background in agile development practices and leading technical design reviews
- Experience mentoring junior engineers and driving engineering standards across a team
Senior Software Development Engineer Jobs in Wisconsin: Frequently Asked Questions
How do you become a senior software development engineer in Wisconsin?
Software engineering in Wisconsin carries no state-issued license or board registration, so the path runs through education and experience. Most Wisconsin employers expect a bachelor's degree in computer science, software engineering, or a closely related field, followed by several years of progressively responsible development work. Candidates who have led system design, mentored peers, and delivered complex projects at Wisconsin-based companies in healthcare IT, fintech, or enterprise software are consistently the strongest hires.
How much do senior software development engineers make in Wisconsin?
Senior software development engineers in Wisconsin earn a median of about $122,660 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $77,710 for the lowest 10% to over $168,630 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire senior software development engineers in Wisconsin?
Wisconsin senior software development engineer roles are posted by GE HealthCare, Baird, and Google and others right now, based on current listings on Migrate Mate as of November 2026. Wisconsin's concentration of healthcare IT firms, insurance and financial services headquarters, and payment technology companies means openings appear across a notably broad range of industries compared with many Midwest states.
Which Wisconsin cities have the most senior software development engineer jobs?
Madison, Milwaukee, and Waukesha account for the largest share of senior software development engineer openings in Wisconsin. Milwaukee leads because of its deep financial services and insurance sector anchored by firms like Northwestern Mutual and Fiserv, Madison draws heavily from Epic Systems and the University of Wisconsin tech ecosystem, and smaller metros like Appleton and Green Bay contribute openings tied to regional manufacturing and insurance employers that maintain in-house engineering teams.
Are there remote senior software development engineer jobs in Wisconsin?
Yes, and more than most fields. About 65% of senior software development engineer openings tied to Wisconsin are remote or hybrid as of November 2026, reflecting how naturally the role lends itself to distributed work. The portions of the role most commonly offered as fully remote are backend platform work and individual-contributor architecture roles, while positions that involve leading on-site teams or embedded client delivery tend to require in-person presence.
How can I get hired as a senior software development engineer in Wisconsin with little or no experience?
The most realistic entry path is through an associate or software engineer role at a Wisconsin employer that runs formal development programs for new graduates. Epic Systems in Verona runs a well-known technical implementation and development track for recent graduates, and Northwestern Mutual and Fiserv in Milwaukee both hire associate software engineers who move into senior roles over time. Building a portfolio of personal or open-source projects demonstrating system design thinking, and earning a cloud certification from AWS or Google, gives candidates a concrete edge when experience is limited.
Where can I find and apply to senior software development engineer jobs in Wisconsin?
You can find and apply to senior software development engineer jobs in Wisconsin on Migrate Mate, which lists current Wisconsin openings updated regularly. Search the listings for roles that match your experience and target location, then apply directly to the ones that fit.
See All 43 Senior Software Development Engineer Jobs in Wisconsin
Find roles in Wisconsin that match your experience and apply in just a few clicks.
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