Mid Level Systems Development Engineer Jobs
Mid level systems development engineer jobs go to engineers ready to own complex systems end to end, drive architectural decisions with limited oversight, and mentor junior teammates through technical challenges. Openings 50% remote or hybrid cover Technology & Software, E-Commerce & Online Marketplaces, and Retail, with Amazon, Amazon Web Services, and Apple among the employers hiring at this level now.
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Systems Development Engineer II
Location: On-site, Portsmouth, NH. Relocation assistance is available for eligible candidates and their families, if needed.
The Systems Engineer will be responsible for the design, implementation, and maintenance of our critical IT infrastructure, ensuring optimal performance and reliability across our network and server environments.
What you will get:
- An agile career and dynamic working culture.
- An inclusive and ethical workplace.
- Competitive salary and performance-based bonuses.
- 401(k) matching plan.
- Competitive compensation programs that reward high performance.
- Comprehensive medical, dental, and vision insurance.
Access to our full list of global benefits: https://www.lonza.com/careers/benefits
What you will do:
- Syncade/Moda Subject Matter Expert for Manufacturing Execution Systems.
- Design, configure, and maintain Cisco network equipment, including routers, switches, and firewalls, ensuring high availability and robust security.
- Install, configure, and manage Microsoft Windows Server operating systems, including Active Directory, DNS, DHCP, and Group Policy.
- Implement and administer virtualized environments using VMware vSphere, including host management, virtual machine provisioning, and resource allocation.
- Monitor system performance and proactively identify and resolve issues related to network, server, and virtualization infrastructure.
- Participate in on-call rotations to provide 24/7 support for critical systems.
- Develop and maintain documentation for system configurations, processes, and procedures.
- Collaborate with other IT teams and departments to support business objectives and project requirements.
- Ensure compliance with company IT policies, security standards, and regulatory requirements.
- Assist in the planning and execution of system upgrades, migrations, and disaster recovery initiatives.
What we are looking for:
- Bachelor's degree in Computer Science, Information Technology, or a related field, or equivalent practical experience.
- Minimum of 3-5 years of experience in systems administration or network engineering.
- Proven expertise in configuring and managing Cisco network equipment (e.g., CCNA or equivalent experience).
- Strong proficiency in Microsoft Windows Server administration, including hands-on experience with Active Directory and related services.
- Demonstrable experience with VMware vSphere, including ESXi hosts, vCenter Server, and virtual machine management.
- Solid understanding of networking concepts (TCP/IP, routing, switching, VLANs).
- Strong communication and interpersonal skills, with the ability to work effectively in a team environment.
- Relevant certifications (e.g., CCNP, MCSA, VCP) are a plus.
About Lonza
At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.
Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.
Ready to shape the future of life sciences? Apply now.
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Who's Hiring



Top Industries Hiring
- Technology & Software
- E-Commerce & Online Marketplaces
- Retail
- Energy
- Manufacturing
Mid Level Systems Development Engineer Jobs: Frequently Asked Questions
How do I get a mid level systems development engineer job?
Position yourself around ownership, not just contribution. Highlight projects where you led design or delivery, reduced system downtime, improved build pipelines, or introduced tooling that the broader team adopted. Tailor your resume to show measurable impact at scale. Mid level hiring managers want evidence that you operate with autonomy, not just that you completed assigned tickets under close supervision.
Which companies hire mid level systems development engineers?
Companies hiring mid level systems development engineers right now include Amazon, Amazon Web Services, and Apple, based on current listings on Migrate Mate as of August 2026. Hiring at this level comes from a broad mix of technology-driven enterprises, cloud infrastructure teams, and large-scale platform organizations that need engineers who can take on substantial ownership without requiring heavy direction.
Are there remote mid level systems development engineer jobs?
Yes, remote and hybrid options are widely available at this experience level. About 50% of mid level systems development engineer openings are remote or hybrid as of August 2026, reflecting how distributed engineering teams have become standard across infrastructure, platform, and tooling functions. On-site roles still exist, particularly at employers with physical data centers or hardware-adjacent work.
How do I move up to a mid level systems development engineer role?
Growth from entry level to mid level comes from accumulating project ownership over time. Early on, focus on deepening your understanding of one or two core systems rather than sampling many. Take on tasks that require debugging under pressure, improving reliability, or reducing manual toil. Demonstrating that your contributions raised the quality or velocity of your team is what shifts you from execution to ownership.
Which industries hire the most mid level systems development engineers?
Mid Level systems development engineer roles concentrate in Technology & Software, E-Commerce & Online Marketplaces, and Retail, based on current listings on Migrate Mate as of August 2026. These sectors invest heavily at the mid level because they operate complex, high-availability systems that require engineers capable of owning reliability, scalability, and tooling improvements without constant senior oversight.