Systems Engineer Jobs in Indianapolis, IN

Systems Engineer jobs in Indianapolis are concentrated in the tech, defense, and healthcare sectors, with hiring hubs in the Meridian-Kessler corridor, Downtown, and the Keystone at the Crossing area. Employers posting right now include V2X, Johnson Controls, and Eli Lilly. Scan the live roles below and apply to whichever ones fit.

Find Systems Engineer Jobs

Overview

Open roles44
Top employerV2X
Work type79% On-site
Top credentialBachelor's degree in engineering
Companies hiring21

Showing 5 of 44+ Systems Engineer jobs

Raytheon
Senior Systems Integration Engineer
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Raytheon
New 1m ago
Senior Systems Integration Engineer
Raytheon
Indianapolis, Indiana
IT Support
Systems Administration
Technical Program Management
On-Site
Bachelor's degree in engineering
10,000+

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V2X
Principal Systems Engineer
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V2X
New 1m ago
Principal Systems Engineer
V2X
Indianapolis, Indiana
Business Strategy
Product Management
Project & Program Management
Project Management
On-Site
Bachelor's degree in engineering
10,000+

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V2X
Sr. Principal Systems Engineer
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V2X
New 1m ago
Sr. Principal Systems Engineer
V2X
Indianapolis, Indiana
Business Strategy
Product Management
Project & Program Management
Project Management
On-Site
Bachelor's degree in engineering
10,000+

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Rolls-Royce
Structural Systems Design Engineer
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Rolls-Royce
New 1m ago
Structural Systems Design Engineer
Rolls-Royce
Indianapolis, Indiana
Engineering (Non-Software)
Manufacturing Engineering
Quality Control
Hybrid
Bachelor's degree in engineering
10,000+

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Eli Lilly
Systems Engineer (P2-P4)
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Eli Lilly
New 1m ago
Systems Engineer (P2-P4)
Eli Lilly
Indianapolis, Indiana
Customer Support
Software Engineering
Technical Program Management
On-Site
Master's degree
10,000+

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See All 44 Systems Engineer Jobs in Indianapolis

Find roles in Indianapolis that match your experience and apply in just a few clicks.

Find Systems Engineer Jobs

Systems Engineer Job Market in Indianapolis

Who's Hiring

  • V2X
    V2X10
  • Johnson Controls
    Johnson Controls6
  • Eli Lilly
    Eli Lilly4
  • Carrier
    Carrier3
  • Allison Transmission
    Allison Transmission2

Top Industries Hiring

  • Aerospace & Defense8
  • Manufacturing7
  • Biotechnology & Pharmaceuticals4
  • Government & Public Sector2
  • Consulting & Professional Services2

Systems Engineer Jobs in Indianapolis: Frequently Asked Questions

How do I get a systems engineer job in Indianapolis?

Target Indianapolis's strongest hiring sectors: defense contracting, healthcare IT, and manufacturing technology. Companies in the North Meridian and Keystone corridors as well as the Fishers and Carmel suburbs post frequently. Candidates who hold active security clearances or have experience with systems integration in regulated industries stand out. Tailoring your application to the specific domain, defense, clinical, or industrial, gives you a real edge over generalist applicants.

Which companies hire systems engineers in Indianapolis?

Indianapolis systems engineer roles are posted by V2X, Johnson Controls, and Eli Lilly and others right now, based on current listings on Migrate Mate as of July 2026. The local market blends large defense primes, regional health systems, and mid-size manufacturing and logistics firms, all of which run dedicated systems engineering teams.

Are there remote systems engineer jobs in Indianapolis?

Yes, though availability depends heavily on the role: hands-on systems integration and lab-based work is almost always on-site, while architecture, documentation, and analytical positions run more readily as hybrid or fully remote. About 21% of systems engineer openings tied to Indianapolis are remote or hybrid as of July 2026. The remote-friendliest Indianapolis roles tend to sit within enterprise IT and software-defined systems teams rather than in defense or manufacturing environments.

How can I get a systems engineer job in Indianapolis with little or no experience?

The most realistic entry path in Indianapolis is through junior or associate systems roles at regional defense contractors and healthcare technology firms, many of whom actively hire candidates fresh from Purdue, IUPUI, or Rose-Hulman with relevant project experience. Help desk, network technician, and IT operations roles at Indianapolis-based health systems and logistics companies often serve as stepping stones. A clearance-eligible background, even without an active clearance, opens additional doors with the city's growing defense sector.

Which industries hire the most systems engineers in Indianapolis?

Indianapolis systems engineer roles concentrate in Aerospace & Defense, Manufacturing, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of July 2026. Indianapolis's position as a logistics hub, combined with its large health system footprint and proximity to major defense installations, makes those sectors the consistent drivers of local systems engineering demand.

See All 44 Systems Engineer Jobs in Indianapolis

Find roles in Indianapolis that match your experience and apply in just a few clicks.

Find Systems Engineer Jobs