System Administrator Visa Sponsorship Jobs in Massachusetts
System administrator visa sponsorship jobs in Massachusetts are concentrated in Greater Boston, where major employers like MIT, Harvard, Mass General Brigham, and companies in the Route 128 technology corridor regularly hire for IT infrastructure roles. The state's dense mix of universities, healthcare systems, and defense contractors creates steady demand for experienced sysadmins.
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Get Access To All JobsPrincipal System Administrator - LIMS
About Astellas
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.
Are you driven to make a real difference in the lives of patients?
We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.
Purpose & Scope
The Principal System Administrator defines requirements for implementation and ongoing operation of validated digital systems and serves as the primary interface between Operations and IT. The role supports user and role management, master data and system configuration for platforms including LIMS and electronic batch record applications, while supporting site data integrity and 21 CFR Part 11 compliance for manufacturing and laboratory equipment.
Role and Responsibilities
- Develop and maintain system configuration documentation and plans for new products, equipment, and workflows, and provide first-line troubleshooting support to users.
- Manage systems in a validated environment and develop policies and procedures supporting compliance requirements.
- Partner with end users to develop user requirements and configuration documents and coordinate vendor installation and operational qualification activities.
- Develop, revise, and review SOPs, protocols, reports, and other controlled documents supporting equipment, platforms, and computerized systems.
- Provide computerized system training, administer system access, support compliance with applicable cGMP regulations and SOPs, and support internal and external audits.
- Manage system updates, change controls, maintenance activities, and associated operational documentation.
- Troubleshoot issues, solve problems, and support investigations and deviations involving software systems.
- Create and manage master data supporting existing and new system functionality.
- Collect and report system and compliance metrics.
- Maintain the integrity and accuracy of documentation and assess compliance with protocols, SOPs, company policies, and applicable regulations.
Required Qualifications
- B.S. degree in biological sciences, cell biology, chemistry, or a related field with 7+ years of relevant experience, or M.S. degree with 5+ years of relevant experience working with analytical computerized systems.
- Experience implementing and managing LIMS and translating laboratory user requirements into IT implementations.
- Hands-on laboratory experience with a variety of analytical computerized systems.
- Expertise in regulations governing data integrity and computerized systems.
- Experience qualifying analytical equipment, including equipment with computerized systems.
- Experience with electronic document management systems.
- Strong knowledge of GMP, SOPs, quality control processes, quality systems, and regulatory requirements.
- Experience with Windows operating systems, domains, networks, and basic computing infrastructure in laboratory or production environments.
- Strong interpersonal and collaboration skills within multidisciplinary teams.
- Good to excellent technical writing and verbal communication skills.
- Ability to manage multiple concurrent tasks in a fast-paced team environment.
- Highly self-motivated and goal oriented, with a demonstrated commitment to quality standards and high-quality data.
Preferred Qualifications
- Hands-on experience implementing and managing Labware LIMS.
- Experience in a start-up, high-growth, fast-paced work environment.
- Experience with instrument integration and direct data capture from stand-alone commercial off-the-shelf systems into a LIMS application.
Location and Working Environment
- This position is based in Westborough, Massachusetts, and requires on-site work in a cGMP-regulated manufacturing facility.
- The role frequently requires extended periods of sitting or standing, use of hands, and regular movement including bending and stooping, with lifting up to 20 pounds.
- Occasional travel to other Astellas manufacturing facilities may be required (0-5%).
- Occasional weekend work as needed to accommodate production schedule.
What awaits you at Astellas?
- Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
- Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
- Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
- A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.
Our Organizational Values and Behaviors
Values: Innovation, Integrity and Impact sit at the heart of what we do.
Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
Salary Range
$105,280-$150,400 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations.)
Benefits:
- Medical, Dental and Vision Insurance
- Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
- 401(k) match and annual company contribution
- Company paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
- Long Term Incentive Plan for eligible positions
- Company fleet vehicle for eligible positions
- Referral bonus program
LI-TR1
Principal System Administrator - LIMS
About Astellas
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.
Are you driven to make a real difference in the lives of patients?
We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.
Purpose & Scope
The Principal System Administrator defines requirements for implementation and ongoing operation of validated digital systems and serves as the primary interface between Operations and IT. The role supports user and role management, master data and system configuration for platforms including LIMS and electronic batch record applications, while supporting site data integrity and 21 CFR Part 11 compliance for manufacturing and laboratory equipment.
Role and Responsibilities
- Develop and maintain system configuration documentation and plans for new products, equipment, and workflows, and provide first-line troubleshooting support to users.
- Manage systems in a validated environment and develop policies and procedures supporting compliance requirements.
- Partner with end users to develop user requirements and configuration documents and coordinate vendor installation and operational qualification activities.
- Develop, revise, and review SOPs, protocols, reports, and other controlled documents supporting equipment, platforms, and computerized systems.
- Provide computerized system training, administer system access, support compliance with applicable cGMP regulations and SOPs, and support internal and external audits.
- Manage system updates, change controls, maintenance activities, and associated operational documentation.
- Troubleshoot issues, solve problems, and support investigations and deviations involving software systems.
- Create and manage master data supporting existing and new system functionality.
- Collect and report system and compliance metrics.
- Maintain the integrity and accuracy of documentation and assess compliance with protocols, SOPs, company policies, and applicable regulations.
Required Qualifications
- B.S. degree in biological sciences, cell biology, chemistry, or a related field with 7+ years of relevant experience, or M.S. degree with 5+ years of relevant experience working with analytical computerized systems.
- Experience implementing and managing LIMS and translating laboratory user requirements into IT implementations.
- Hands-on laboratory experience with a variety of analytical computerized systems.
- Expertise in regulations governing data integrity and computerized systems.
- Experience qualifying analytical equipment, including equipment with computerized systems.
- Experience with electronic document management systems.
- Strong knowledge of GMP, SOPs, quality control processes, quality systems, and regulatory requirements.
- Experience with Windows operating systems, domains, networks, and basic computing infrastructure in laboratory or production environments.
- Strong interpersonal and collaboration skills within multidisciplinary teams.
- Good to excellent technical writing and verbal communication skills.
- Ability to manage multiple concurrent tasks in a fast-paced team environment.
- Highly self-motivated and goal oriented, with a demonstrated commitment to quality standards and high-quality data.
Preferred Qualifications
- Hands-on experience implementing and managing Labware LIMS.
- Experience in a start-up, high-growth, fast-paced work environment.
- Experience with instrument integration and direct data capture from stand-alone commercial off-the-shelf systems into a LIMS application.
Location and Working Environment
- This position is based in Westborough, Massachusetts, and requires on-site work in a cGMP-regulated manufacturing facility.
- The role frequently requires extended periods of sitting or standing, use of hands, and regular movement including bending and stooping, with lifting up to 20 pounds.
- Occasional travel to other Astellas manufacturing facilities may be required (0-5%).
- Occasional weekend work as needed to accommodate production schedule.
What awaits you at Astellas?
- Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
- Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
- Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
- A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.
Our Organizational Values and Behaviors
Values: Innovation, Integrity and Impact sit at the heart of what we do.
Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
Salary Range
$105,280-$150,400 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations.)
Benefits:
- Medical, Dental and Vision Insurance
- Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
- 401(k) match and annual company contribution
- Company paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
- Long Term Incentive Plan for eligible positions
- Company fleet vehicle for eligible positions
- Referral bonus program
LI-TR1
System Administrator Job Roles in Massachusetts
See all 87+ System Administrator Jobs in Massachusetts
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Search System Administrator Jobs in MassachusettsSystem Administrator Jobs in Massachusetts: Frequently Asked Questions
Which companies sponsor visas for system administrators in Massachusetts?
Large Massachusetts employers with consistent H-1B visa sponsorship histories for system administrator roles include Mass General Brigham, Boston Children's Hospital, MIT, Harvard University, Raytheon Technologies, and IBM. Mid-size managed service providers and financial institutions in Boston's financial district also appear regularly in Department of Labor LCA disclosure data for system administrator positions.
Which visa types are most common for system administrator roles in Massachusetts?
The H-1B is the most common visa category for system administrators in Massachusetts, provided the role qualifies as a specialty occupation requiring a bachelor's degree in computer science, information systems, or a directly related field. Some employers, particularly universities and research institutions, also sponsor TN visas for Canadian and Mexican nationals and, in rarer cases, O-1 visas for candidates with exceptional credentials.
Which cities in Massachusetts have the most system administrator sponsorship jobs?
Boston and Cambridge account for the largest share of system administrator sponsorship activity in Massachusetts, driven by major healthcare networks, universities, and technology firms concentrated there. Worcester is a secondary hub with a growing healthcare and higher-education sector. Burlington and Waltham along the Route 128 corridor also see consistent demand from mid-size and enterprise technology companies.
How to find system administrator visa sponsorship jobs in Massachusetts?
Migrate Mate filters job listings specifically for visa sponsorship, making it straightforward to browse system administrator roles in Massachusetts without sorting through positions that won't support work authorization. You can search by role and state to surface employers actively hiring sysadmins who are open to sponsoring H-1B or other work visas, saving significant time compared to unfiltered job searches.
Are there any state-specific considerations for system administrators seeking sponsorship in Massachusetts?
Massachusetts has a large concentration of defense contractors such as Raytheon and Leidos that hire system administrators, but many of those roles require security clearances that are generally unavailable to foreign nationals, which limits sponsorship in that segment. The state's university and healthcare sectors offer more accessible pathways. Massachusetts also has an active H-1B dependent employer base, so reviewing an employer's LCA filings on the Department of Labor's public disclosure portal before applying can clarify their sponsorship track record.
What is the prevailing wage for sponsored system administrator jobs in Massachusetts?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.