INTRODUCTION

Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.

Legend Biotech is seeking an Associate Medical Director, Insights & Executive Engagements as part of the Medical Affairs team based Remotely.

Role Overview

The Associate Medical Director, Insights & Engagements, plays a critical role within the Medical Affairs organization supporting the strategic scientific and medical leadership for CARVYKTI. This role is responsible for the design and oversight of structured, centralized insight generation activities that will lead to actionable clinical and scientific insights by engaging with key opinion leaders (KOLs), cell therapy centers, and leading academic institutions and thereby inform the U.S. medical strategy.

In addition to contributing to the overall CARVYKTI medical strategy, the Associate Medical Director leads the execution strategy of national and regional insight-generation initiatives, including advisory boards, expert roundtables, and strategic scientific engagements. The individual will also lead the planning and execution of medical engagement activities at major scientific congresses and collaborate with leading U.S. cell therapy institutions on executive scientific projects. AMD will be working in close collaboration with cross-functional colleagues ensuring excellent coordination of all engagement related activities.

The role will also support the interpretation and internal communication of emerging safety themes derived from aggregated real world experience, advisory boards, and scientific exchange related to Carvykti. In collaboration with pharmacovigilance and cross-functional partners, the Associate Medical Director will help ensure that safety considerations and real-world clinical experiences are translated into medical strategy recommendations, evidence gaps, and future evidence generation priorities alongside the Real-World Evidence Generation Team.

Given the global partnership for CARVYKTI, the Associate Medical Director will work in close collaboration with cross-functional colleagues from Johnson & Johnson to ensure alignment on medical strategy, insight generation, scientific exchange, congress activities, site activation and OOS activities. The role will help facilitate effective coordination across organizations to support the shared goal of advancing scientific understanding and optimal clinical use of CARVYKTI.

This position requires strong scientific expertise, strategic thinking, and the ability to engage credibly with leading clinicians, investigators, and institutional leaders in the field of hematologic malignancies and cell therapy and will report directly to the Medical Scientific Director of US MA Strategy.

Key Responsibilities

Insights Generation & Expert Engagement:

• Leads the planning and execution of national and regional insight-generation activities, including Advisory Boards, small-group strategy meetings, scientific exchange sessions with key clinical leaders
• Capture, synthesize, and communicate strategic insights from KOLs, treatment centers, and investigators to inform medical strategy and lifecycle planning.
• Build and maintain strong scientific relationships with leading U.S. cell therapy institutions and academic experts.
• Identify emerging trends, unmet needs, and barriers to CAR-T implementation within treatment centers.

Executive Scientific Engagements:

• Develop and lead executive-level scientific collaborations with key academic institutions, transplant programs, and CAR-T centers.
• Partner with institutional leaders and experts on strategic scientific initiatives and projects designed to address key clinical and operational questions in CAR-T therapy.
• Support initiatives that promote thought leadership and scientific dialogue within the U.S. cell therapy ecosystem.

Congress Strategy & Execution

• Lead Medical Affairs planning and execution for major hematology and oncology congresses
• Coordinate CARVYKTI-related medical activities during congress including: Advisory meetings and KOL engagements, Scientific discussions and expert exchanges, Internal insight capture and post-congress reporting
• Translate congress findings and expert discussions into strategic insights and actionable recommendations for internal stakeholders.

Safety & Medical Governance

• Contribute to the scientific monitoring of safety information related to CARVYKTI through expert engagements, congress discussions, and clinical insights.
• Capture and communicate emerging safety perspectives from clinicians and treatment centers.
• Collaborate with pharmacovigilance, medical safety, and cross-functional teams to ensure appropriate escalation and alignment on safety-related insights.
• Support scientific exchange and education related to risk management and safe use of CAR-T therapies.

Alliance & Cross-Company Collaboration

• Collaborate closely with Medical Affairs Alliance counterparts at to ensure alignment on U.S. medical strategy and key scientific priorities related to CARVYKTI.
• Support joint Legend–J&J planning processes including advisory board strategy, congress engagement planning, and key expert interactions.
• Facilitate the exchange and synthesis of insights across both organizations to inform medical strategy.
• Participate in alliance medical meetings, cross-company working groups, and strategic discussions to support effective partnership execution.
• Partner with Field Medical, Clinical Development, HEOR, Market Access, and Commercial teams to ensure alignment on key initiatives and engagements.
• Contribute to the identification of evidence gaps and opportunities for real-world evidence or investigator-initiated research.
• Support internal insight dissemination and strategic decision-making through clear scientific communication.

Decision Making

The Associate Medical Director will typically have the authority to make decisions related to direction, methodologies, approaches in the engagement strategy and execution. They may also make decisions related to project execution, including timelines, milestones and resource allocation within budget. Higher-level approvals are required for those related to significant budget allocations, strategic shifts, or major collaborations that have substantial financial or long-term implications.

Requirements

• MD, PharmD, or PhD in life sciences, medicine, or a related scientific discipline preferred; other advanced medical degree (NP, PA, etc.) considered.
• 3–6+ years of experience in Medical Affairs, Clinical Development, or related roles within the pharmaceutical or biotechnology industry.
• Experience in hematology/oncology, preferably multiple myeloma, or cell therapy.
• Experience interacting with KOLs, academic institutions, and clinical investigators.
• Experience planning or supporting advisory boards, scientific meetings, or congress activities preferred.
• Demonstrated success in managing complex projects and working in cross-functional teams in a matrix environment with a results focused attitude.
• Excellent written and verbal communication skills, with the ability to translate complex scientific concepts into actionable insights for diverse audiences.
• Demonstrated proficiency with the most current computer operating systems, Microsoft Office 2013 (particularly Outlook, Word, Excel, and PowerPoint).
• SharePoint, Adobe Acrobat Professional, Concur, Veeva and other PC-based applications. Familiar with AI based platforms including Copilot.

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Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.

EEO Statement

It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.

Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.

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