Senior Software Development Engineer Visa Sponsorship Jobs in Tennessee

INTRODUCTION

St. Jude Children’s Research Hospital is seeking a Senior Software Developer to join our team. This position reports to the Director of High Performance Research Computing and works closely with the Center for Bioimage Informatics as a collaborative team member.

The Center for Bioimage Informatics is a dynamic, close-knit, and focused team dedicated to supporting the life-changing research conducted at St. Jude by developing and applying innovative AI and computer vision approaches for image analysis and quantification. We are looking for an individual motivated to make a meaningful impact through software development focused on image generation, management, analysis, and processing.

ROLE AND RESPONSIBILITIES

The ideal candidate will have proven experience in full-stack, open-source web development, with strong proficiency in Java, Python, and JavaScript, as well as modern application frameworks such as Node.js and Spring. Experience with RESTful API design and integration, including familiarity with Model Context Protocol (MCP) or similar tool-calling frameworks, is expected. Experience with relational database technologies is required, with PostgreSQL experience strongly preferred.

Given the bioimaging focus of this work, experience with image formats, OME Bio-Formats, microscopy techniques, imaging systems, and AI/ML-driven software development is a plus. Additional technologies in use include Docker, Maven, Git, Zarr, and Dask.

Candidates should demonstrate experience designing and developing object-oriented software solutions. This is a hands-on development role in which the successful candidate will spend a significant portion of their time architecting, building, integrating, and testing software as part of robust, production-ready solutions.

The Senior Software Developer is responsible for developing software to support object-oriented software applications. This is an onsite role in Memphis, TN.

Other tasks:
- Leads software coding, testing, debugging, documenting, and installation, and may be responsible for one or more of these components, as directed.
- Leads the design of the system’s graphical user interface.
- Assists in developing detailed specifications for programs to be written for enterprise-wide systems.
- Develops the detailed specifications from which programs will be written for group-level systems.

Job Responsibilities:

- Perform the detailed design, coding and testing of software utilizing established design/code standards and to the architectural patterns outlined by the architectural team.
- Design and implement new systems and features, as well as modify and maintain existing systems for adaptation to business and/or technology changes.
- Manage projects and provide subject matter expertise for production systems, document maintenance and system support procedures.
- Support continuous improvement by investigating alternatives and new technologies and presenting these for architectural review.
- Determine root cause for the most complex software issues and develop practical, efficient, and permanent technical solutions.
- Collaborate with internal teams and vendors to fix and improve products.
- Remain current on new technologies and available vendor packages; evaluate and make recommendations as necessary.
- Train and mentor junior teams on emerging technology systems and applications related aspects.
- Perform other duties as assigned to meet the goals and objectives of the department and institution.
- Maintains regular and predictable attendance.

MINIMUM QUALIFICATIONS

- Bachelor's degree in computer science, data science, information science, business, or related field required.

MINIMUM EXPERIENCE

- Minimum experience: 4+ years of IT experience in systems programming and development, preferably in comparable industry.
- Experience in SDLC methodologies (e.g. Agile, Waterfall, CI/CD).
- Experience in software systems design and maintenance.
- Experience working with business stakeholders to identify and document Requirements.
- Proven performance in earlier role/comparable role.

PREFERRED QUALIFICATIONS

- Proven experience in full-stack, open-source web development with strong proficiency in Java, Python, and JavaScript.
- Experience with modern application frameworks such as Node.js and Spring.
- Experience with RESTful API design and integration, including familiarity with agentic AI frameworks such as Model Context Protocol (MCP) or similar tool-calling protocols.
- PostgreSQL experience strongly preferred.
- Experience with bioimaging technologies including image formats, OME Bio-Formats, microscopy techniques, and imaging systems.
- Experience with AI/ML-driven software development.
- Familiarity with Docker, Maven, Git, Zarr, and/or Dask.
- Experience designing and developing object-oriented software solutions.

COMPENSATION

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Senior Software Developer.

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St. Jude is an Equal Opportunity Employer

No Search Firms

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.