Senior Director Of Product Jobs in USA with Visa Sponsorship
Senior Director of Product roles attract strong H-1B visa and O-1 visa sponsorship from tech companies, but competition is fierce and the specialty occupation bar is high. Most sponsors require a bachelor's degree in computer science, engineering, or a related field, plus a decade or more of product leadership experience. For detailed occupation requirements, see the O*NET profile.
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Get Access To All JobsWhy Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
- Physical and Emotional Wellness
- Financial Wellness
- Support for Caregivers
The Importance of the Role
Job Title: Head of New Product Strategy and Commercialization
Department: Commercial Operations
Reports to: VP, Commercial Operations
Location: Cambridge, MA
The Opportunity to Make a Difference
The Position:
The Head of New Product Strategy and Commercialization is responsible for the global commercial strategy of our pipeline of best-in-class siRNA assets. As the Head of New Product Strategy and Commercialization, you will co-lead the program Asset Team with an R&D co-lead accountable for shaping and advancing asset strategy in partnership with cross-functional peers. The individual must be able to drive timely, high-quality decisions, align diverse stakeholders across a complex matrix organization, and be accountable for recommendations and outcomes to executive management that impact the asset.
In your capacity as program Asset Co-Lead you will work across the portfolio and in partnership with the Global Brand Team, Global Development Team, Medical Affairs, Market Access, Commercial Operations, Clinical Development, and Patient Advocacy. For our later-stage assets, you will be accountable for actionable brand strategic and tactical plans to optimize launch readiness and commercial success, including disease awareness communications for multiple stakeholders, such as HCPs and patients/caregivers, to ensure market preparation.
This role also partners closely with Business Development to provide commercial assessments of external opportunities and support discussions on potential external partnerships.
Primary Responsibilities Include:
Head of New Product Strategy and Commercialization
- Own the asset strategic roadmap and long-term vision, ensuring commercial perspective is embedded in enterprise decision-making
- Be accountable for delivery of the asset objectives against corporate goals, including key strategic recommendations, trade-off decisions, and execution milestones
- Drive asset-level cross-functional decision-making by integrating functional input, resolving ambiguity, and escalating critical issues when needed
- Identify, assess, and elevate asset-level risks and opportunities, with clear ownership of mitigation strategies and decision follow-through
- Lead the development of target product profiles for pipeline assets, based on thorough understanding of market dynamics and potential future trends
- Partner with Market Access, Medical, and HEOR to build evidence and value strategies that support payer engagement and access for commercialization
- Partner with Commercial Operations and Manufacturing to develop integrated forecasts and market potential assessments
- Lead commercial assessments of potential therapeutic targets and programs
Desired Education and Skills:
- Bachelor’s degree with 15+ years or (MBA preferred with 13+ years) of experience in biotech/pharma strategic roles with a track record demonstrating accountability, sense of urgency and cross functional leadership
- Strong commercial acumen with significant experience in commercial strategy, brand marketing, brand strategy, and product management is required; global product launch experience in rare disease is preferred
- Extensive understanding of drug development and proven track record of using deep customer and market insight to deliver informed recommendations to R&D decisions that ensure attainment of commercial objectives
- Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities
- Strong leadership abilities to influence and lead across a matrix environment, drive timely cross-functional decisions, and be accountable for asset-level recommendations and outcomes
- Experience in high science, competitive markets required
- Experience supporting business development through commercial opportunity assessment and due diligence, including evaluation of external assets, markets, and strategic fit
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
What Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
LI-Hybrid
This position is hybrid, you will be expected to work on site at one of Sarepta’s facilities in the United States and/or attend Company-sponsored in-person events from time to time.
The targeted salary range for this position is $222,400 - $278,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
- Physical and Emotional Wellness
- Financial Wellness
- Support for Caregivers
The Importance of the Role
Job Title: Head of New Product Strategy and Commercialization
Department: Commercial Operations
Reports to: VP, Commercial Operations
Location: Cambridge, MA
The Opportunity to Make a Difference
The Position:
The Head of New Product Strategy and Commercialization is responsible for the global commercial strategy of our pipeline of best-in-class siRNA assets. As the Head of New Product Strategy and Commercialization, you will co-lead the program Asset Team with an R&D co-lead accountable for shaping and advancing asset strategy in partnership with cross-functional peers. The individual must be able to drive timely, high-quality decisions, align diverse stakeholders across a complex matrix organization, and be accountable for recommendations and outcomes to executive management that impact the asset.
In your capacity as program Asset Co-Lead you will work across the portfolio and in partnership with the Global Brand Team, Global Development Team, Medical Affairs, Market Access, Commercial Operations, Clinical Development, and Patient Advocacy. For our later-stage assets, you will be accountable for actionable brand strategic and tactical plans to optimize launch readiness and commercial success, including disease awareness communications for multiple stakeholders, such as HCPs and patients/caregivers, to ensure market preparation.
This role also partners closely with Business Development to provide commercial assessments of external opportunities and support discussions on potential external partnerships.
Primary Responsibilities Include:
Head of New Product Strategy and Commercialization
- Own the asset strategic roadmap and long-term vision, ensuring commercial perspective is embedded in enterprise decision-making
- Be accountable for delivery of the asset objectives against corporate goals, including key strategic recommendations, trade-off decisions, and execution milestones
- Drive asset-level cross-functional decision-making by integrating functional input, resolving ambiguity, and escalating critical issues when needed
- Identify, assess, and elevate asset-level risks and opportunities, with clear ownership of mitigation strategies and decision follow-through
- Lead the development of target product profiles for pipeline assets, based on thorough understanding of market dynamics and potential future trends
- Partner with Market Access, Medical, and HEOR to build evidence and value strategies that support payer engagement and access for commercialization
- Partner with Commercial Operations and Manufacturing to develop integrated forecasts and market potential assessments
- Lead commercial assessments of potential therapeutic targets and programs
Desired Education and Skills:
- Bachelor’s degree with 15+ years or (MBA preferred with 13+ years) of experience in biotech/pharma strategic roles with a track record demonstrating accountability, sense of urgency and cross functional leadership
- Strong commercial acumen with significant experience in commercial strategy, brand marketing, brand strategy, and product management is required; global product launch experience in rare disease is preferred
- Extensive understanding of drug development and proven track record of using deep customer and market insight to deliver informed recommendations to R&D decisions that ensure attainment of commercial objectives
- Excellent organizational skills, sufficient to multi-task in an extremely fast-paced environment with changing priorities
- Strong leadership abilities to influence and lead across a matrix environment, drive timely cross-functional decisions, and be accountable for asset-level recommendations and outcomes
- Experience in high science, competitive markets required
- Experience supporting business development through commercial opportunity assessment and due diligence, including evaluation of external assets, markets, and strategic fit
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
What Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
LI-Hybrid
This position is hybrid, you will be expected to work on site at one of Sarepta’s facilities in the United States and/or attend Company-sponsored in-person events from time to time.
The targeted salary range for this position is $222,400 - $278,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.
Candidates must be authorized to work in the U.S.
Sarepta Therapeutics offers a competitive compensation and benefit package.
Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
See all 9,775+ Senior Director Of Product Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Senior Director Of Product roles.
Get Access To All JobsTips for Finding Senior Director Of Product Jobs
Target companies with established immigration programs
Large tech companies with dedicated legal teams sponsor Senior Director of Product roles far more reliably than early-stage startups. Look for employers with a track record of H-1B filings for senior product leadership, not just individual contributor roles.
Position your degree as a match for the role
USCIS scrutinizes specialty occupation status for senior product roles. A degree in computer science, engineering, or business with a technical focus strengthens your case considerably more than an unrelated field paired with experience alone.
Document your leadership scope in concrete terms
O-1A petitions for senior product leaders require evidence of extraordinary ability. Quantify your impact: teams led, revenue influenced, products shipped at scale, and any industry recognition. Vague leadership claims rarely satisfy adjudicators.
Engage an immigration attorney before accepting an offer
Senior director titles can trigger additional USCIS scrutiny around whether the role genuinely requires a specialty degree. An attorney can assess your specific situation and help frame the petition before your employer begins the process.
Understand the H-1B lottery timeline before your start date
If you need a new H-1B, registration opens in March with a lottery in late March or early April. Offer timing matters: starting a role in October requires your employer to file months in advance, so plan accordingly.
Ask employers about cap-exempt options if you have existing H-1B status
If you currently hold H-1B status with another employer, a transfer to a new sponsor does not require the lottery. This makes you significantly more attractive to hiring managers who would otherwise face a year-long wait.
Frequently Asked Questions
Do Senior Director of Product roles qualify as H-1B specialty occupations?
Yes, but with more scrutiny than individual contributor roles. USCIS requires that the position normally requires a bachelor's degree or higher in a specific specialty. Senior Director of Product roles typically qualify when the job description ties the position to a technical field like computer science or engineering, rather than framing it as general management. Employers with prior successful H-1B visa filings for similar titles are a safer bet.
What visa types are most common for Senior Director of Product sponsorship?
H-1B is the most common path for Senior Director of Product candidates who don't already have permanent residence. O-1A is worth considering if you have strong evidence of extraordinary ability, such as keynote speaker invitations, patents, or coverage in major industry publications. L-1A applies if you're transferring within a multinational company in a managerial or executive capacity. Browse current openings on Migrate Mate to see which employers are actively sponsoring this title.
Does my degree field matter when applying for Senior Director of Product roles with visa sponsorship?
It matters more than most candidates expect. USCIS requires that the petitioned position normally requires a degree in a specific specialty. For product leadership, degrees in computer science, engineering, or business with a quantitative or technical focus are the strongest fit. If your degree is in an unrelated field, an attorney can sometimes build the case using a combination of education and progressive specialized experience, though approval is less certain.
How does the H-1B lottery affect the hiring timeline for Senior Director of Product positions?
If you need a cap-subject H-1B, your employment can't begin before October 1 of that fiscal year, and your employer must file in April. That's a six-month gap that many companies won't absorb for senior roles, which is why employers often prefer candidates who already hold H-1B status or are on OPT. If you're in either of those situations, your candidacy is meaningfully stronger and the lottery is not a factor.
Are Senior Director of Product roles realistically available with visa sponsorship?
Yes, particularly at mid-to-large technology companies, enterprise software firms, and well-funded scale-ups with established HR and legal infrastructure. Sponsorship at the director and VP level is more common than many candidates assume, because these companies recruit internationally for senior talent. The key is targeting employers who have filed H-1B petitions for senior product roles before. Migrate Mate filters sponsoring employers specifically, so you can focus your search on companies that are already set up to sponsor.
What is the prevailing wage requirement for sponsored Senior Director Of Product jobs?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.