Applications Specialist Jobs in Massachusetts

Applications Specialist jobs in Massachusetts are actively hiring, with demand concentrated in healthcare IT, life sciences, and enterprise software across one of the country's most technology-intensive state economies. Boston, Cambridge, and Worcester account for the bulk of openings, where anchor employers like Mass General Brigham, Oracle, and Thermo Fisher Scientific maintain large application support and implementation teams. The most sought-after specialties are EHR and clinical applications, CRM platform administration, and enterprise resource planning support. See the openings below and apply to the ones that match your experience.

Find Applications Specialist Jobs

Overview

Open roles6
Top employerUMass Memorial Health
Top cityBoston, MA
Cities hiring4
Work type75% Remote
Top credentialMaster's degree

Showing 5 of 6+ Applications Specialist jobs

Harvard University
Business Applications Specialist
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Harvard University
Added 2d ago
Business Applications Specialist
Harvard University
Cambridge, Massachusetts
Business Strategy
Consulting & Professional Services
Strategy & Corporate Development
Hybrid
Bachelor's degree in business administration
1,001-5,000

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UMass Memorial Health
Epic Applications Systems Specialist, Radiant
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UMass Memorial Health
Added 3d ago
Epic Applications Systems Specialist, Radiant
UMass Memorial Health
Worcester, Massachusetts
Project Management
Solutions Engineering & Architecture
Technical Program Management
$83k.8 - $150k.59/yr
Remote (US)
Bachelor's degree
10,000+

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UMass Memorial Health
EPIC/Workday Security Applications Specialist
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UMass Memorial Health
Added 4d ago
EPIC/Workday Security Applications Specialist
UMass Memorial Health
Worcester, Massachusetts
Corporate Training
Educational Administration
Program Management
$83k.8 - $150k.59/yr
Remote (US)
Bachelor's degree
10,000+

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Leica Biosystems
Field Applications Specialist - Core Histology
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Leica Biosystems
Added 1w ago
Field Applications Specialist - Core Histology
Leica Biosystems
Boston, Massachusetts
Project Management
Solutions Engineering & Architecture
Technical Program Management
$90k - $105k/yr
Remote (US)
Master's degree
5,001-10,000

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H
Applications Specialist - Laboratory Automation
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H
Added 3w ago
Applications Specialist - Laboratory Automation
HIGHRES
Beverly, Massachusetts
Business Development
Customer Success
Program Management
Project Management
$110k - $170k/yr
Bachelor of Science

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See All 6 Applications Specialist Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Applications Specialist Jobs

Applications Specialist Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Boston
2 jobs
Worcester
2 jobs
Beverly
1 job
Cambridge
1 job

Applications Specialist Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

UMass Memorial Health
UMass Memorial Health2 open roles
H
HIGHRES1 open role
Leica Biosystems
Leica Biosystems1 open role

What Massachusetts Employers Look For

The qualifications that appear most often in applications specialist jobs across Massachusetts.

  • Bachelor's degree in information technology, computer science, or a related field
  • Two or more years of hands-on experience configuring or supporting enterprise applications
  • Proficiency with at least one major platform such as Epic, Salesforce, or SAP
  • Strong troubleshooting skills with the ability to resolve application issues independently
  • Experience working cross-functionally with clinical, operations, or business teams
  • Familiarity with ITIL service management practices or formal ticketing systems

Applications Specialist Jobs in Massachusetts: Frequently Asked Questions

How do you become a applications specialist in Massachusetts?

Most applications specialist roles in Massachusetts require a bachelor's degree in information technology, computer science, or a closely related discipline paired with hands-on platform experience. Massachusetts has no state-issued license specific to this role, but employer-recognized certifications in platforms like Epic, Salesforce, or ServiceNow carry significant weight with Boston-area healthcare systems and life sciences firms. Many candidates enter through help desk or business analyst roles at large Massachusetts employers before moving into dedicated application support positions.

Which companies hire applications specialists in Massachusetts?

Companies currently hiring applications specialists in Massachusetts include UMass Memorial Health, HIGHRES, and Leica Biosystems, per current listings on Migrate Mate as of October 2026. Massachusetts's dense concentration of academic medical centers, biotech firms, and financial services companies means openings appear consistently across both large enterprise organizations and mid-size software vendors headquartered in the Greater Boston area.

Which Massachusetts cities have the most applications specialist jobs?

Boston, Worcester, and Beverly lead Massachusetts for applications specialist openings. Boston and Cambridge dominate because of the region's concentration of major hospital systems, university research institutions, and technology companies, while Worcester draws consistent demand from UMass Memorial Health and the city's growing life sciences and manufacturing sectors.

Are there remote applications specialist jobs in Massachusetts?

Yes, and more than most fields, since applications specialist work is largely desk-based and software-driven. About 100% of applications specialist openings tied to Massachusetts are remote or hybrid as of October 2026, reflecting the role's suitability for distributed teams. Configuration, user support, and documentation tasks are most likely to be offered remotely, while go-live implementations and on-site training engagements typically require in-person presence.

How can I get hired as a applications specialist in Massachusetts with little or no experience?

The most realistic entry path is a help desk or IT support analyst role at a large Massachusetts employer, which builds the platform familiarity hiring managers look for. Mass General Brigham, Boston Children's Hospital, and major enterprise software vendors in the Boston area regularly bring on associates and new graduates through structured IT rotational or entry-level support programs. Earning a platform-specific certification, such as Salesforce Administrator or Epic credentialing through a registered training partner, substantially improves a candidate's standing even without direct applications specialist experience.

Where can I find and apply to applications specialist jobs in Massachusetts?

You can find and apply to applications specialist jobs in Massachusetts on Migrate Mate, which lists current openings across the state. Search the listings to find roles that match your background and apply directly to the ones that fit.

See All 6 Applications Specialist Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Applications Specialist Jobs