Associate Engineering Manager Jobs
Associate Engineering Manager jobs are open across software, hardware, and infrastructure engineering, hired from startups to enterprise across tech, fintech, and manufacturing, at every level from senior individual contributor to director-track people lead. Find a role that fits below and apply directly.
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Job Description
General Summary:
Vertex is seeking a lab-based Process Development Engineering Senior Scientific Associate to support large-scale bioprocess development in a GLP pilot laboratory environment. The role focuses on the reliable execution of mammalian and stem cell culture studies in 3–10 L and 50–200 L single-use bioreactors, including perfusion-based processes. The associate will help establish reproducible operations as processes move from smaller-scale studies into pilot-scale systems.
This position is responsible for hands-on bioreactor preparation and operation, seed-train and culture support, media preparation and exchange, sampling, cell counting, harvest, and equipment turnaround. The associate will work with process development, engineering/facilities, and analytical teams to coordinate studies, maintain equipment readiness, and produce complete, traceable records. Work will be performed in accordance with applicable site procedures, safety requirements, data-integrity expectations, and GLP requirements where applicable to the study.
Key Duties and Responsibilities:
- Plan and execute pilot-scale process-development studies using Eppendorf, Sartorius, and other applicable single-use bioreactor and perfusion platforms.
- Prepare bioreactor systems for operation, including single-use assembly installation, tubing and connection setup, sensor checks, pre-run verification, and documentation of equipment readiness.
- Support seed-train activities and mammalian and stem cell culture expansion from smaller-scale vessels into 3–10 L and 50–200 L systems, using established aseptic techniques (i.e. operation of sterile tube connectors and welders).
- Operate and monitor culture processes, including feeds, media exchange, perfusion, sampling, and harvest, according to approved protocols and study plans.
- Track process parameters and culture performance, identify unexpected trends, and promptly communicate potential impacts on study execution or sample quality.
- Prepare media and process solutions; manage transfers, sampling, and sample handoff while maintaining appropriate labeling, traceability, and handling conditions.
- Operate, clean, maintain, and perform first-line troubleshooting on bioreactors, perfusion equipment, single-use mixers, cell counters, pumps, sensors, and ancillary analyzers.
- Coordinate maintenance, calibration, consumables, and equipment turnover to keep the pilot lab ready for scheduled studies.
- Follow controlled laboratory procedures and contribute to improvements in setup, aseptic operations, study execution, and equipment workflows.
- Record activities, observations, equipment status, and study data accurately and contemporaneously in Benchling and other required records. Support discrepancy investigation and escalation in accordance with applicable procedures.
- Compile data summaries and contribute to protocols, technical reports, and study documentation.
- Collaborate with analytical partners on sampling plans and timely sample processing, and with engineering/facilities partners on equipment and utility needs.
- Participate in study planning, experimental-design discussions, troubleshooting, and initiatives to reduce operational variability during scale-up.
- Participate in weekend work rotations as needed to support ongoing cell-culture and bioreactor operations.
Knowledge and Skills:
- Strong hands-on mammalian cell-culture experience, including stem cell culture, and consistently effective aseptic technique.
- Experience operating bioreactors and supporting scale-up of cell-culture processes; familiarity with 50–200 L single-use systems and perfusion workflows is strongly preferred.
- Understanding of seed-train planning, media and feed preparation, process monitoring, sampling, and harvest operations.
- Ability to recognize process deviations, equipment issues, and potential sources of variability, and to troubleshoot or escalate them appropriately.
- Experience with manual, automated, or semi-automated workflows, including liquid handling, sample processing, and cell counting; experience with SUBs/SUMs or comparable systems is preferred.
- Strong technical documentation habits, attention to detail, and understanding of data integrity and traceability in a controlled laboratory environment.
- Ability to coordinate time-sensitive activities across process development, analytical, and engineering/facilities teams while maintaining safety and quality standards.
- Clear communication skills and a practical approach to improving reproducibility and laboratory efficiency.
Education and Experience:
- Bachelor's or Master’s degree in a relevant scientific/engineering field is required.
- Bachelor's degree and 2–4 years of experience or a Master's degree and 0–2 years of experience or the equivalent combination of education and experience.
- Relevant experience must include mammalian cell culture and aseptic laboratory practices. Experience in a pilot lab or other controlled laboratory environment, particularly with large-scale single-use bioreactors, perfusion, or process-development scale-up is preferred.
At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.
Pay Range:
$73,900 - $110,900
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
On-Site Designated
Flex Eligibility Status:
In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
LI-Onsite
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
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Who's Hiring
- Lockheed Martin187

- L3Harris39

- Mesa Associates24

- UPS20

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Top Industries Hiring
- Consulting & Professional Services54
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What Employers Look For
The qualifications that appear most often in associate engineering manager jobs.
- 2-5 years of software engineering experience with at least one year in a tech lead or team lead role
- Demonstrated ability to manage or mentor engineers in a professional setting
- Proficiency in at least one primary engineering stack relevant to the team's domain
- Experience working within agile or scrum delivery frameworks
- Strong written and verbal communication skills for cross-functional collaboration
- Bachelor's degree in computer science, engineering, or a related technical field
Tips for Your Associate Engineering Manager Job Search
Tailor your resume for people leadership
Highlight moments where you influenced team velocity, mentored engineers, or unblocked delivery, not just technical output. Associate engineering manager roles are evaluated on leadership signal, so make those moments explicit and specific, not buried in a list of technologies.
Apply early to roles that fit
Migrate Mate lists associate engineering manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Show scope in your engineering experience
Hiring managers want to see that you owned something end-to-end. Quantify team size, number of services, or delivery cycles you led. Even informal tech lead experience reads as management readiness when framed around accountability and coordination.
Prepare a people-leadership story for every interview
Expect at least one behavioral round focused entirely on how you've handled underperformance, conflict, or competing priorities on a team. Candidates who arrive without a clear example from real experience lose ground quickly to those who do.
Negotiate scope, not just compensation
At the associate level, the number of direct reports and the team's stage matter as much as the offer itself. A team of two in stealth mode and a team of eight mid-scale require very different skills. Clarify both before accepting.
Target companies with structured eng manager ladders
Some companies promote strong engineers into vague hybrid roles with no clear path forward. Look for job descriptions that define what success looks like at six and twelve months, and ask in the interview how the manager role is scoped from individual contributor work.
Associate Engineering Manager Jobs: Frequently Asked Questions
Which companies are hiring the most associate engineering managers?
The most active employers for associate engineering managers right now are Lockheed Martin, L3Harris, and Mesa Associates, and the most openings are in Texas, Florida, and California, based on current listings on Migrate Mate as of November 2026. Demand is especially high at companies scaling product teams through rapid growth phases.
How many associate engineering manager jobs are remote?
About 55% of associate engineering manager openings are fully remote or hybrid as of November 2026, reflecting the people-coordination demands of the role. Backend platform and infrastructure teams tend to have the highest share of remote openings, while embedded systems and hardware-adjacent teams typically require on-site presence.
How do you become an associate engineering manager?
Most associate engineering managers move into the role after demonstrating leadership as a senior engineer or tech lead. The path typically involves taking on mentorship responsibilities, leading sprint planning or cross-team coordination, and expressing interest in a management track with your current manager. Some companies have formal rotational or internal promotion programs, while others hire externally from candidates with adjacent lead experience.
Can you get an associate engineering manager job with little management experience?
Yes, many companies hire into associate engineering manager roles from strong individual contributors who have informal leadership experience. If you've led a project, mentored junior engineers, or coordinated work across teams, those experiences are relevant. Framing your resume to highlight ownership, influence, and coordination rather than pure technical output will make a material difference in how your application reads.
What does the associate engineering manager interview process look like?
The process typically includes a recruiter screen, a hiring manager conversation focused on leadership style and experience, one or more behavioral rounds using structured situational questions, and sometimes a system design or technical discussion to confirm engineering fluency. Some companies add a panel round with engineers or cross-functional partners to assess collaboration and communication skills before extending an offer.
Where can I find and apply to associate engineering manager jobs?
You can find and apply to associate engineering manager jobs on Migrate Mate, which lists current openings from across the United States. Find roles that match your experience and apply directly to each listing from the page.
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