Clinical Assistant Jobs in Philadelphia, PA
Clinical Assistant jobs in Philadelphia are in strong demand, concentrated in University City, Center City, and North Philadelphia across academic medical centers, hospital networks, and outpatient specialty clinics. Employers hiring right now include Thomas Jefferson University & Jefferson Health, Saint Joseph's University, and The IMA. See the openings below and apply to the ones that match your experience.
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JOB SUMMARY:
Responsible for oversight of laboratory operations, vaccine programs, clinical supply chain and management of the medical assistant team. Ensures standardized, compliant, and efficient workflows across sites and supports development of clinical programs and quality improvement interventions.
Strong oral and written communication skills required. Must communicate effectively with patients, staff, and leadership and contribute to a positive, collaborative environment. Must work effectively across disciplines including nursing, behavioral health, pharmacy, and medical providers.
KEY RESPONSIBILITIES:
Supervisory:
- Directly supervises Medical Assistants
- Provides individual and group supervision in accordance with CBA
- Enforces policies and procedures, utilizing coaching and corrective action as needed
- Participates in hiring, onboarding, and training
- Oversees scheduling and staffing in coordination with site needs
- Monitors productivity and workflow expectations
- Supports staff development and competencies
Laboratory Operations:
- Oversees all laboratory operations across sites
- Ensures compliance with CLIA-waived testing requirements
- Oversees QA/QC processes for point-of-care testing
- Develops and maintains lab policies and procedures
- Ensures staff competency for all testing performed
- Prepares for and participates in audits
- Coordinates with external lab vendors
- Ensures proper specimen handling and workflow standardization
Vaccines / Supplies / Equipment:
- Oversees vaccine program including inventory, storage, and compliance
- Ensures temperature monitoring and documentation
- Oversees clinical supply systems across sites
- Ensures disposal of expired supplies per policy
- Coordinates ordering of vaccines and supplies
Quality Improvement and Program Development:
- Supports development and implementation of quality improvement workflows and clinical programs that involve the Medical Assistant team, laboratory and vaccine services
- Participates in cross-functional initiatives to improve care delivery
- Assists in standardizing workflows across sites
Other:
- Participates in supervision, departmental meetings, and staff meetings
- Collaborates with Director on leadership development and organizational priorities
- All other tasks as assigned
GENERAL QUALIFICATIONS:
- Registered Nurse strongly preferred.
- A bachelor’s degree in laboratory science, healthcare administration, or a related field; or extensive professional experience in a comparable laboratory or clinical operations leadership role required.
- Ambulatory care experience required
- Experience with laboratory operations and point-of-care testing required
- Experience with managing vaccine programs required
- Supervisory experience required
- Phlebotomy and lab processing and CLIA-waived testing experience preferred
- Experience with quality improvement and regulatory compliance preferred
- Strong organizational, communication, and problem-solving skills
- Ability to work independently and meet deadlines
- Ability to work effectively in a multidisciplinary environment
Clearances
- Background checks required, including Criminal Background, Child Abuse, and FBI Clearances
Physical Requirements
- This position requires the ability to sit and stand for extended periods of time and to move around within a building and between clinical sites.
- Occasional lifting/carrying of items <35 pounds
- The ability to communicate using written and spoken words
- Must have all necessary vaccinations
- Tb clearance
The above statements describe the general nature of the work being performed by the individual assigned to this position. This is not intended to be an exhaustive list of all responsibilities and duties. Employees may be directed to perform tasks other than those specifically described in this description.
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Find Clinical Assistant JobsClinical Assistant Job Market in Philadelphia
Who's Hiring
- Thomas Jefferson University & Jefferson Health23

- Saint Joseph's University15

- The IMA8

- Mazzoni Center8
- Solis Mammography8

Top Industries Hiring
- Healthcare & Medical Services
Clinical Assistant Jobs in Philadelphia: Frequently Asked Questions
How do I get a clinical assistant job in Philadelphia?
Focus your search on Philadelphia's academic medical centers and large hospital networks, which generate the highest volume of clinical assistant openings in the city. University City anchors a dense cluster of healthcare employers, while Northeast Philadelphia and the suburbs along the Main Line add steady outpatient and specialty clinic volume. Candidates with phlebotomy, EHR documentation, or patient intake experience stand out in this market.
Which companies hire clinical assistants in Philadelphia?
Philadelphia clinical assistant roles are posted by Thomas Jefferson University & Jefferson Health, Saint Joseph's University, and The IMA and others right now, based on current listings on Migrate Mate as of October 2026. The Philadelphia market is shaped by a mix of major academic health systems, regional hospital networks, and a growing number of outpatient specialty and urgent care practices.
How can I get a clinical assistant job in Philadelphia with little or no experience?
The most realistic entry path in Philadelphia is through a medical assistant training program at a community college or vocational school, several of which are based in or near the city. Philadelphia's large federally qualified health centers and community health networks actively hire entry-level candidates and provide on-the-job training. Volunteering or completing a practicum at a Philadelphia hospital system is a common way to convert into a paid role.
Which industries hire the most clinical assistants in Philadelphia?
Philadelphia clinical assistant roles concentrate in Healthcare & Medical Services, based on current listings on Migrate Mate as of October 2026. Philadelphia's identity as a major academic medicine hub, anchored by its cluster of research universities and teaching hospitals, drives outsized demand relative to comparably sized cities.
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