Clinical Informatics Nurse Jobs

Clinical Informatics Nurse jobs are open across hospitals, health systems, integrated delivery networks, and health IT vendors, from staff-level to manager and director, with specializations in EHR implementation, clinical decision support, and workflow optimization. Find a role that fits below and apply directly.

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Overview

Open roles174+
Top stateCalifornia
Top employerCVS Health
Top citySacramento, CA
Work type46% On-site
Top industryHealthcare

Showing 5 of 174+ Clinical Informatics Nurse jobs

Clinical Innovation & Informatics, Health Informatics BI Analyst
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New 21h ago
Clinical Innovation & Informatics, Health Informatics BI Analyst
Siemens Healthineers
Remote
Business Analysis
Business Operations
Data Analytics
$113k - $156k/yr
Remote (US)
Bachelor's degree
10,000+

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Clinical Informatics Specialist
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New 22h ago
Clinical Informatics Specialist
Ascension
Milwaukee, Wisconsin
Biotech & Life Sciences
Clinical Trials
Healthcare Administration
$79k.88 - $146k.05/yr
Hybrid
High school diploma or GED
10,000+

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Pharmacist, Clinical Informatics
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Added 1d ago
Pharmacist, Clinical Informatics
Emplify Health
La Crosse, Wisconsin
Clinical Support
Healthcare Administration
Pharmacy
$125k - $188k/yr
Six Sigma Certification
5,001-10,000

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IT Clinical Informatics Pharmacist
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Added 1d ago
IT Clinical Informatics Pharmacist
Foundation Health Partners
Fairbanks, Alaska
Customer Success
Program Management
Project & Program Management
Project Management
$36.44 - $58.3/hr
Bachelor's degree
1,001-5,000

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Director Clinical Informatics and Practice Transformation-SWHR
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Added 1d ago
Director Clinical Informatics and Practice Transformation-SWHR
Southwestern Health Resources
Dallas, Texas
Business Operations
Business Strategy
Consulting & Professional Services
Hybrid
Master's degree
501-1,000

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Clinical Informatics Nurse Job Market

Who's Hiring

  • CVS Health10
  • Cone Health5
  • Medpace4
  • Sutter Health4
  • Ascension3

Top Industries Hiring

  • Healthcare & Medical Services19
  • Insurance9
  • Biotechnology & Pharmaceuticals3
  • Education2
  • Science & Research2

What Employers Look For

The qualifications that appear most often in clinical informatics nurse jobs.

  • Active registered nurse license with two or more years of direct clinical experience
  • Hands-on experience with at least one major EHR platform such as Epic or Cerner
  • Informatics certification such as ANCC's RN-BC in Nursing Informatics preferred or required
  • Demonstrated ability to build or configure clinical decision support tools and order sets
  • Experience training clinical staff on new workflows or system upgrades
  • Bachelor of Science in Nursing with preference for a graduate degree in health informatics or a related field

Tips for Your Clinical Informatics Nurse Job Search

Tailor your resume to EHR platforms

List every EHR system you've worked in by name, including version if relevant, and note whether your experience was end-user, superuser, or build-side. Hiring managers screen for specific platforms, and a vague 'EHR experience' line gets passed over fast.

Highlight workflow redesign you led

Clinical informatics roles require evidence that you've changed how clinicians work, not just trained them on a system. Describe a specific workflow you analyzed, the problem it solved, and which department adopted it. Concrete outcomes beat credentials in most postings.

Filter openings by implementation phase

Job postings often signal where a health system is in its EHR lifecycle: pre-go-live, optimization, or post-implementation support. Match your experience to that phase and call it out in your cover letter so recruiters can place you immediately.

Apply early to roles that fit

Migrate Mate lists clinical informatics nurse openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Prepare for scenario-based interview questions

Interviewers in this field routinely ask you to walk through a build decision, a go-live issue, or a clinical resistance situation. Practice narrating a specific case with a clear beginning, decision point, and outcome before your first interview.

Negotiate scope before discussing title

Many clinical informatics offers look similar on paper but differ in whether you have build access, a seat in governance meetings, or authority to recommend policy changes. Clarify which systems you'll own and what sign-off you'll need before accepting any offer.

Clinical Informatics Nurse Jobs: Frequently Asked Questions

Which companies are hiring the most clinical informatics nurses?

The most active employers for clinical informatics nurses right now are CVS Health, Cone Health, and Medpace, and the most openings are in California, North Carolina, and Texas, based on current listings on Migrate Mate as of November 2026. Large integrated health systems and EHR implementation vendors typically post the highest volume of these roles.

How many clinical informatics nurse jobs are remote?

About 54% of clinical informatics nurse openings are fully remote or hybrid as of November 2026, reflecting strong demand for virtual implementation support and training. Roles focused on training delivery, documentation governance, and clinical decision support build work tend to allow the most schedule flexibility compared to go-live command center positions.

How do you become a clinical informatics nurse?

Start by earning your registered nurse license and working directly with patients long enough to understand clinical workflows from the inside. From there, seek out EHR superuser or trainer responsibilities within your current role, then pursue a graduate certificate or degree in health informatics. The ANCC Nursing Informatics certification signals readiness for a dedicated informatics position and is listed as preferred or required in most postings.

Can you get a clinical informatics nurse job with little experience?

Some entry-level informatics roles are open to nurses who have strong clinical backgrounds but limited informatics experience, particularly at health systems rolling out a new EHR. Volunteering as a superuser or joining an implementation task force while still in a bedside role is the fastest way to build a credible informatics resume before you apply for a full transition.

What does the clinical informatics nurse interview process look like?

Most processes include an initial screening call, a technical interview where you walk through a past build or workflow redesign, and a panel with clinical leaders or IT project managers. Some employers add a scenario exercise asking you to identify a workflow gap and propose a solution. References from physicians or nursing managers who can speak to your analytical work carry significant weight at the offer stage.

Where can I find and apply to clinical informatics nurse jobs?

You can find and apply to clinical informatics nurse jobs on Migrate Mate, which lists current openings from across the United States. Find the roles that fit your specialty, experience level, and preferred location, then apply directly to each listing from the page.

See All 174+ Clinical Informatics Nurse Jobs

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