Clinical Manager Jobs in Cambridge, MA
Clinical Manager jobs in Cambridge, Massachusetts concentrate in Kendall Square, East Cambridge, and the Alewife corridor, driven by demand from biotech, academic medical, and life sciences employers including Moderna, Relay Therapeutics, and Biogen. Opportunities range from outpatient and inpatient program management to clinical operations leadership. See the openings below and apply to the ones that match your experience.
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The Opportunity
The Sr. Manager, Clinical Business Operations will be responsible for managing vendor selection, contracts, budgets and performance metrics. This person will develop and leverage relationships with external vendors for strong business results and know how to structure service agreements/contracts to drive accountability, quality and performance. This role is a key partner to the clinical study teams and will partner with senior level stakeholders to ensure vendors are achieving committed goals and service levels in accordance with executed contracts, budgets and timelines.
Your Role:
- You will identify, engage and contract with clinical vendors as well manage relationships with key vendor stakeholders.
- You will manage the RFP and vendor selection process.
- You will oversee the negotiation and execution of contractual agreements and change orders.
- You will work with the clinical study leads and cross-functional teams to establish governance process, which may include joint oversight committees, with key clinical vendors to monitor service levels and key performance indicators and manage issue escalation and resolution.
- You will partner with finance on the monthly accruals.
- You will provide support for financial planning and the financial management of clinical studies, including developing more efficient processes to calculate budgets and track expenses.
- You will proactively identify opportunities for operational and process improvements and efficiencies.
Your Background:
- You should ideally have 10+ years of experience in clinical vendor management and/or clinical financial management. Sponsor experience is strongly preferred.
- You have extensive experience with all aspects of vendor oversight or alliance management: vendor selection, RFP process, contract development, and selection to performance management and continuous improvement of the vendor relationships.
- You have expertise working with cross-functional teams, such as clinical operations, finance, legal, quality, systems and process, as well as with corresponding vendor functions
- You have a strong understanding of clinical development phase activity finance with hands on financial analytics experience
- You have effective negotiation, project management and creative problem-solving skills
- You have excellent analytical and quantitative skills
- You are a motivated self-starter who is capable of flourishing in a fast-paced small company environment.
- You are a creative problem-solver with excellent communication and public speaking skills.
- You have strong interpersonal and organizational skills, with a high degree of attention to detail.
- You are pragmatic and able to manage multiple projects and needs effectively.
Estimated Salary Range: [$124,000-$177,000]
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.
#BP1
About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!
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Find Clinical Manager JobsClinical Manager Job Market in Cambridge
Who's Hiring
- Moderna30

- Relay Therapeutics30

- Biogen10

- Sodexo10

- Philips10

Top Industries Hiring
- Science & Research20
- Biotechnology & Pharmaceuticals10
- Consulting & Professional Services10
Clinical Manager Jobs in Cambridge: Frequently Asked Questions
How do I get a clinical manager job in Cambridge?
Focus your search on Kendall Square's dense biotech and pharma cluster, the academic medical centers anchored near Harvard and MIT, and the growing life sciences corridor along the Alewife corridor. Employers in Cambridge typically prioritize candidates with direct program or departmental leadership experience, familiarity with regulated clinical environments, and a demonstrated ability to manage multidisciplinary teams. Tailoring your resume to the specific sector, whether research-driven biotech or ambulatory care, gives you a meaningful edge in this competitive local market.
Which companies hire clinical managers in Cambridge?
Employers hiring clinical managers in Cambridge right now include Moderna, Relay Therapeutics, and Biogen, based on current listings on Migrate Mate as of August 2026. Cambridge's employer mix leans heavily toward research hospitals, biotechnology firms, and specialty care organizations, many of which maintain both clinical and operational management roles across their Cambridge campuses.
Are there remote clinical manager jobs in Cambridge?
Yes, but with limits. Clinical manager roles are often tied to on-site oversight of staff and patient-facing programs, making fully remote positions less common than in purely desk-based fields. About 63% of clinical manager openings tied to Cambridge are remote or hybrid as of August 2026, and those arrangements tend to concentrate in care coordination, utilization management, and clinical operations roles where direct facility presence is less essential.
How can I get a clinical manager job in Cambridge with little or no experience?
The most realistic entry path in Cambridge is moving into a team lead or senior clinician role at one of the city's academic medical affiliates or larger biotech-sponsored clinical programs, then stepping into management from there. Cambridge employers frequently hire charge nurses, senior coordinators, and clinical supervisors as developmental roles before promoting into full management. Volunteering for quality improvement or compliance projects within your current organization also signals readiness for the supervisory responsibilities Cambridge employers expect.
Which industries hire the most clinical managers in Cambridge?
The sectors hiring the most clinical managers in Cambridge are Science & Research, Biotechnology & Pharmaceuticals, and Consulting & Professional Services, based on current listings on Migrate Mate as of August 2026. Cambridge's concentration of research institutions, biotechnology campuses, and hospital-affiliated outpatient programs creates sustained demand for clinical managers who can operate at the intersection of patient care delivery and organizational leadership.
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