Clinical Nurse Jobs in Jacksonville, FL
Clinical Nurse jobs in Jacksonville, Florida are concentrated in Southside, Riverside, and the Downtown Medical District, with strong demand across acute care, outpatient clinics, and long-term care. Employers actively hiring include HCA Florida Memorial Hospital, Ascension, and Healogics. Find a role that fits below and apply directly.
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How you'll make an impact in this role:
- Provide advanced direct nursing care in accordance with established policies, procedures and protocols of the healthcare organization. Master of Science in Nursing (MSN) or Doctor of Nursing Practice (DNP) from an accredited CNS program.
- Active APRN / CNS Licensure and Board Certification (AGCNS-BC or equivalent). Certified Neuroscience Registered Nurse (CNRN) or Stroke Certified Registered Nurse (SCRN) preferred. Minimum of 3–5 years of clinical expertise in neuro-critical care or interventional neurovascular nursing
- Serve as an expert consultant for staff in areas of program development, clinical practice, and professional development. Contributes to defining, directing and evaluating the nursing care and functions of clinical staff.
- Manage clinical research projects in support of evidence-based practice and disseminates findings.
- Develop, implement and evaluate educational plans/programs and utilizes methods, measurements and tools to evaluate achievement of learning goals.
- BLS Provider obtained within 1 Month (30 days) of hire date or job transfer date required. American Heart Association or American Red Cross accepted.
- Clinical Nurse Specialist obtained prior to hire date or job transfer date required.
- Registered Nurse obtained prior to hire date or job transfer date required.
- Diploma from an accredited school/college of nursing required and Master's degree required.
Equal employment opportunity employer
Ascension provides Equal Employment Opportunities (EEO) to all associates and applicants for employment without regard to race, color, religion, sex/gender, sexual orientation, gender identity or expression, pregnancy, childbirth, and related medical conditions, lactation, breastfeeding, national origin, citizenship, age, disability, genetic information, veteran status, marital status, all as defined by applicable law, and any other legally protected status or characteristic in accordance with applicable federal, state and local laws. For further information, view the EEO Know Your Rights (English) poster or EEO Know Your Rights (Spanish) poster.
Fraud prevention notice
Prospective applicants should be vigilant against fraudulent job offers and interview requests. Scammers may use sophisticated tactics to impersonate Ascension employees. To ensure your safety, please remember: Ascension will never ask for payment or to provide banking or financial information as part of the job application or hiring process. Our legitimate email communications will always come from an @ascension.org email address; do not trust other domains, and an official offer will only be extended to candidates who have completed a job application through our authorized applicant tracking system.
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Benefits:
Various health insurance options & wellness plans
Retirement benefits including employer match plans
Long-term & short-term disability
Employee assistance programs (EAP)
Parental leave & adoption assistance
Tuition reimbursement
Ways to give back to your community
Benefit options and eligibility vary by position. Compensation varies based on factors including, but not limited to, experience, skills, education, performance, location and salary range at the time of the offer.
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Find Clinical Nurse JobsClinical Nurse Job Market in Jacksonville
Who's Hiring
- HCA Florida Memorial Hospital97

- Ascension77

- Healogics19

- UF Health19

- Brooks Rehabilitation19

Top Industries Hiring
- Healthcare & Medical Services
Clinical Nurse Jobs in Jacksonville: Frequently Asked Questions
How do I get a clinical nurse job in Jacksonville?
Focus your search on Jacksonville's largest hiring corridors: the Southside medical corridor along Philips Highway, the Downtown Medical District near UF Health, and the growing network of outpatient clinics in the Beaches and Mandarin areas. Acute care hospitals, specialty surgery centers, and pediatric facilities drive the most openings. Candidates with telemetry, emergency, or ICU experience move fastest, and bilingual skills are an edge given the region's diverse patient population.
Which companies hire clinical nurses in Jacksonville?
Companies currently hiring clinical nurses in Jacksonville include HCA Florida Memorial Hospital, Ascension, and Healogics, per current listings on Migrate Mate as of September 2026. Jacksonville's employer mix leans heavily toward large health systems, community hospitals, and a growing number of ambulatory surgery and urgent care networks serving the city's expanding suburban corridors.
Are there remote clinical nurse jobs in Jacksonville?
Yes, though remote opportunities are limited since most clinical nurse roles require hands-on patient care and on-site presence. About 0% of clinical nurse openings tied to Jacksonville are remote or hybrid as of September 2026, with remote roles most common in care management, utilization review, and telehealth triage functions linked to Jacksonville's larger health systems.
How can I get a clinical nurse job in Jacksonville with little or no experience?
The most realistic entry path in Jacksonville is through nurse residency or new-graduate programs offered by the city's large acute care health systems, which regularly recruit recent graduates into structured cohorts. Community health clinics, long-term care facilities, and outpatient primary care practices in the Westside and Northside neighborhoods also hire entry-level nurses. Completing clinical rotations at a Jacksonville facility and pursuing BLS or ACLS certification before applying strengthens any new-graduate application considerably.
Which industries hire the most clinical nurses in Jacksonville?
Jacksonville clinical nurse roles concentrate in Healthcare & Medical Services, based on current listings on Migrate Mate as of September 2026. Jacksonville's position as Northeast Florida's regional medical hub, anchored by major academic medical centers and a large military and veteran health infrastructure, keeps sustained demand across those sectors.
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