Clinical Nurse Jobs in Orlando, FL
Clinical Nurse jobs in Orlando are concentrated in the Medical City corridor near Lake Nona, the downtown health campus around Orange Avenue, and the Sand Lake Road medical district, with strong demand across hospital systems, specialty clinics, and outpatient surgery centers. Employers actively hiring right now include AdventHealth Orlando, CenterWell, and Orlando Health. Scan the live roles below and apply to whichever ones fit.
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Position Summary
- Location = 52. W Underwood St. Orlando, FL 32806
- THREE SHIFTS EACH WEEK
The Clinical Assistant Nurse Manager (CANM) is responsible for leading the shift operations within the clinical setting to ensure delivery of high-quality care, exceptional customer experience, and optimal patient flow. In conjunction with the Department Nursing Operations Manager and the Assistant Nursing Operations Manager (ANOM); the CANM provides guidance, fosters collaboration, and is responsible for the unit's clinical operations including patient care assignments, customer experience, productivity, and quality outcomes in settings where an acute care patient receives active treatment for an injury, episode of illness, a medical condition, or post intervention with assessment.
The 11LP Digestive Health Unit is a 30-bed unit dedicated to caring for patients before and after their procedure at the Digestive Health Institute. Orlando Health Digestive Health Institute is an international destination for care, offering comprehensive and coordinated services to evaluate, diagnose and treat a wide range of conditions affecting the digestive tract and gastrointestinal organs. The institute has distinguished itself worldwide in offering many diagnostic and treatment options, including artificial intelligence (AI) capabilities that improve diagnosis, treatment, and outcomes.
This is one small step in our journey towards establishing a solid organ transplant program. The newly dedicated unit will enable us to provide specialized training to a core team of nurses and staff to meet the specific needs of patients who travel 500 miles to see us and are admitted with complex digestive health problems and be familiar with cutting-edge clinical research protocols.
Common Procedures you will see on this unit:
- Peroral Endoscopic Myotomy (POEM)
- Endoscopic Retrograde Cholangiopancreatography (ERCP)
- Endoscopic Ultrasound (EUS)
- Day One Benefits
- Competitive PTO Program
- Up to 5% Retirement Match
- Tuition Reimbursement & Student Loan Assistance
- Paid Parental Leave
- Fertility & Adoption Benefits
- Employer-Paid Life & Disability Insurance
- Medical, Dental & Vision Coverage
- Career Growth & Education Programs
- Wellness Programs and Employee Discounts
Qualifications:
- Bachelor of Science in Nursing Degree (BSN) preferred.
Licensure/Certification
- Current licensure as a registered nurse in the State of Florida or Nurse Licensure Compact (NLC).
- Current Basic Life Support (BLS) certification.
Experience
- A minimum of one year of experience as a Registered Nurse; acute care setting preferred.
Position Summary
- Location = 52. W Underwood St. Orlando, FL 32806
- THREE SHIFTS EACH WEEK
The Clinical Assistant Nurse Manager (CANM) is responsible for leading the shift operations within the clinical setting to ensure delivery of high-quality care, exceptional customer experience, and optimal patient flow. In conjunction with the Department Nursing Operations Manager and the Assistant Nursing Operations Manager (ANOM); the CANM provides guidance, fosters collaboration, and is responsible for the unit's clinical operations including patient care assignments, customer experience, productivity, and quality outcomes in settings where an acute care patient receives active treatment for an injury, episode of illness, a medical condition, or post intervention with assessment.
The 11LP Digestive Health Unit is a 30-bed unit dedicated to caring for patients before and after their procedure at the Digestive Health Institute. Orlando Health Digestive Health Institute is an international destination for care, offering comprehensive and coordinated services to evaluate, diagnose and treat a wide range of conditions affecting the digestive tract and gastrointestinal organs. The institute has distinguished itself worldwide in offering many diagnostic and treatment options, including artificial intelligence (AI) capabilities that improve diagnosis, treatment, and outcomes.
This is one small step in our journey towards establishing a solid organ transplant program. The newly dedicated unit will enable us to provide specialized training to a core team of nurses and staff to meet the specific needs of patients who travel 500 miles to see us and are admitted with complex digestive health problems and be familiar with cutting-edge clinical research protocols.
Common Procedures you will see on this unit:
- Peroral Endoscopic Myotomy (POEM)
- Endoscopic Retrograde Cholangiopancreatography (ERCP)
- Endoscopic Ultrasound (EUS)
- Day One Benefits
- Competitive PTO Program
- Up to 5% Retirement Match
- Tuition Reimbursement & Student Loan Assistance
- Paid Parental Leave
- Fertility & Adoption Benefits
- Employer-Paid Life & Disability Insurance
- Medical, Dental & Vision Coverage
- Career Growth & Education Programs
- Wellness Programs and Employee Discounts
Qualifications:
- Bachelor of Science in Nursing Degree (BSN) preferred.
Licensure/Certification
- Current licensure as a registered nurse in the State of Florida or Nurse Licensure Compact (NLC).
- Current Basic Life Support (BLS) certification.
Experience
- A minimum of one year of experience as a Registered Nurse; acute care setting preferred.
See All 276+ Clinical Nurse Jobs in Orlando
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Find Clinical Nurse JobsClinical Nurse Job Market in Orlando
Who's Hiring
- AdventHealth Orlando83
- CenterWell28
- Orlando Health28
- The Cigna28
- AdventHealth East Orlando28
Clinical Nurse Jobs in Orlando: Frequently Asked Questions
How do I get a clinical nurse job in Orlando?
Focus your search on Orlando's largest hiring clusters: the Lake Nona Medical City complex, the AdventHealth and Orlando Health systems anchoring the metro, and the growing network of ambulatory surgery centers along Sand Lake Road and International Drive. Candidates with acute care or surgical experience move fastest in this market. Applying directly through hospital career portals and targeting specialty units like cardiac, oncology, or orthopedics gives you a clear edge over general applicants.
Which companies hire clinical nurses in Orlando?
Employers hiring clinical nurses in Orlando right now include AdventHealth Orlando, CenterWell, and Orlando Health, based on current listings on Migrate Mate as of November 2026. Orlando's market is anchored by large not-for-profit hospital systems alongside a dense network of outpatient clinics and specialty care centers serving the region's fast-growing population.
How can I get a clinical nurse job in Orlando with little or no experience?
The most realistic entry path in Orlando is applying to new-graduate residency programs offered by the large hospital systems anchoring the metro, which are structured specifically for nurses without acute care experience. Entry-level floor nursing roles in medical-surgical or telemetry units serve as the standard first step. Completing clinical rotations locally through Central Florida nursing programs also builds name recognition with hiring managers at those same institutions.
Related Jobs in Florida
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