Clinical Nurse Jobs in Philadelphia, PA

Clinical Nurse jobs in Philadelphia are in strong demand across the city's dense healthcare corridor, with openings concentrated in Center City, West Philadelphia, and North Philadelphia at academic medical centers, community health systems, and specialty care networks. Employers hiring right now include Penn Medicine, Children's Hospital of Philadelphia, and Thomas Jefferson University & Jefferson Health. See the openings below and apply to the ones that match your experience.

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Overview

Open roles149+
Top employerPenn Medicine
Work type100% On-site
Top credentialCPR Certification
Companies hiring13

Showing 5 of 149+ Clinical Nurse jobs

Penn Medicine
Clinical Nurse 1- Inpatient - Ortho Trauma - Penn Presbyterian Medical Center- 51 N 39th St
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Penn Medicine
Added 1d ago
Clinical Nurse 1- Inpatient - Ortho Trauma - Penn Presbyterian Medical Center- 51 N 39th St
Penn Medicine
Philadelphia, Pennsylvania
Clinical Support
Healthcare Administration
Mental & Behavioral Health
CPR Certification
10,000+

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Penn Medicine
Clinical Nurse 1- Inpatient Medical Oncology, FT Rotating Shifts at HUP
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Penn Medicine
Added 1d ago
Clinical Nurse 1- Inpatient Medical Oncology, FT Rotating Shifts at HUP
Penn Medicine
Philadelphia, Pennsylvania
Clinical Support
Healthcare Administration
Mental & Behavioral Health
CPR Certification
10,000+

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Penn Medicine
Clinical Nurse 2- Med Surg (Cathcart 5)- FT- Days- Pennsylvania Hospital
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Penn Medicine
Added 2d ago
Clinical Nurse 2- Med Surg (Cathcart 5)- FT- Days- Pennsylvania Hospital
Penn Medicine
Philadelphia, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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Children's Hospital of Philadelphia
Clinical Nurse, Sedation Unit - Philadelphia Campus
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Children's Hospital of Philadelphia
Added 2d ago
Clinical Nurse, Sedation Unit - Philadelphia Campus
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
$48.3 - $58.15/hr
CPR Certification
10,000+

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Temple University Health System
Trauma Clinical Nurse Coordinator, Full Time, 7a-3:30p
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Temple University Health System
Added 3d ago
Trauma Clinical Nurse Coordinator, Full Time, 7a-3:30p
Temple University Health System
Philadelphia, Pennsylvania
Business Operations
Customer Service
Customer Success
Master's degree
5,001-10,000

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See All 149+ Clinical Nurse Jobs in Philadelphia

Find roles in Philadelphia that match your experience and apply in just a few clicks.

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Clinical Nurse Job Market in Philadelphia

Who's Hiring

  • Penn Medicine
    Penn Medicine106
  • Children's Hospital of Philadelphia
    Children's Hospital of Philadelphia10
  • Thomas Jefferson University & Jefferson Health
    Thomas Jefferson University & Jefferson Health6
  • GSPP Rehabilitation
    GSPP Rehabilitation4
  • University of Pennsylvania
    University of Pennsylvania4

Top Industries Hiring

  • Education
  • Healthcare & Medical Services

Clinical Nurse Jobs in Philadelphia: Frequently Asked Questions

How do I get a clinical nurse job in Philadelphia?

Philadelphia's strongest hiring comes from its large academic medical systems, federally qualified health centers, and the growing network of outpatient specialty clinics anchored in Center City and West Philadelphia. Candidates with experience in critical care, oncology, or med-surg tend to move fastest through hiring here. Tailoring your application to the specific patient population and unit focus of each employer, rather than sending a generic resume, gives you a clear edge in this market.

Which companies hire clinical nurses in Philadelphia?

Employers hiring clinical nurses in Philadelphia right now include Penn Medicine, Children's Hospital of Philadelphia, and Thomas Jefferson University & Jefferson Health, based on current listings on Migrate Mate as of September 2026. Philadelphia's hiring landscape leans heavily toward large integrated health systems and nationally recognized academic medical centers, alongside a strong base of community hospital networks and specialty care practices.

Are there remote clinical nurse jobs in Philadelphia?

Yes, though remote work is uncommon for clinical nursing given the hands-on, patient-facing nature of most roles. About 0% of clinical nurse openings tied to Philadelphia are remote or hybrid as of September 2026, with those positions most often in utilization review, case management, or telehealth triage rather than direct bedside care.

How can I get a clinical nurse job in Philadelphia with little or no experience?

The most realistic entry path in Philadelphia is applying to structured new-graduate residency programs at the city's major health systems, which are specifically designed to bring RNs with limited hospital experience into supervised clinical rotations. Community health centers and long-term care facilities across neighborhoods like Kensington and Germantown also hire entry-level clinical nurses and offer a volume of hands-on experience that builds a resume quickly. Earning a BLS and ACLS certification before applying strengthens any early-career application in this market.

Which industries hire the most clinical nurses in Philadelphia?

Philadelphia clinical nurse roles concentrate in Education and Healthcare & Medical Services, based on current listings on Migrate Mate as of September 2026. Philadelphia's position as a hub for nationally ranked academic medicine, combined with a large federally qualified health center network serving dense urban neighborhoods, keeps demand across those sectors consistently high.

See All 149+ Clinical Nurse Jobs in Philadelphia

Find roles in Philadelphia that match your experience and apply in just a few clicks.

Find Clinical Nurse Jobs