Clinical Research Manager Jobs in St. Louis, MO
Clinical Research Manager jobs in St. Louis are concentrated in the Cortex Innovation Community, the Central West End medical corridor, and the Grand Center area, driven by academic medical centers, contract research organizations, and pharmaceutical firms. Employers actively hiring include Washington University in St. Louis, Mercy, and Science 37. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 80+ Clinical Research Manager jobs
Location
SAINT LOUIS, MO 63110
Scheduled Hours
40
Position Summary
The Holtz lab is seeking help with a complex observational clinical study at Washington University School of Medicine. The Maternal Offspring Microbiome (MOM) study aims to understand how the infant gut is first populated with bacteria and viruses. We are interested in defining if babies obtain their microbiome from their environment, from the people who care for them, or from their pets.
In this position, you will coordinate a complex clinical research study; serve as a resource to provide comprehensive information to clinical staff by promoting a smooth operation, prepare regulatory compliance and interact with other departments.
You will work closely with other team members and healthcare professionals to recruit and enroll study participants, explain the purpose of study and obtain informed consent from participants, conduct study visits in the hospital and the participant’s home, ensure compliance with protocol guidelines and requirements of the IRB and IACUC, enter data, assist with lab procedures, and perform data analyses.
Preferred applicants are detail orientated, clear communicators, able to provide their own transportation to study visits, curious, enthusiastic, have a flexible schedule (availability needed some weekends, evenings, and early mornings), and have experience with REDCap, Excel, and EPIC.
This position may be responsible for multiple research studies simultaneously.
Primary Duties & Responsibilities:
- Assists in developing plans for research projects and discusses the interpretation of results; collaborates in the preparation of manuscripts for publications and preparation of grant proposals to sponsoring agencies; assists in the preparation of amendments to protocols and/or modifications to study design as appropriate.
- Coordinates the development of forms, questionnaires and the application of research techniques; assists in writing instructional procedure manuals for study progress, data collection and coding; reviews journals, abstracts and scientific literature to keep abreast of new developments and to obtain information regarding previous studies to aid in the planning of new studies.
- Implements and manages all phases of study/protocol; ensures compliance with protocol guidelines and requirements of regulatory agencies; establishes record-keeping systems; makes assessments and determinations of participants’ progress in the study; analyzes, investigates and reports adverse events; makes decisions as when to notify physicians of issues, when to stop participant inclusion and/or to make and/or recommend adjustment of the protocol of particular participants; resolves protocol management issues and recommends corrective action as appropriate; serves as liaison with funding or sponsoring agency.
- Evaluates and interprets collected clinical data as appropriate; prepares oral or written presentations or reports and analyses setting forth progress trends and provides recommendations or conclusions of the same.
- Performs other duties as assigned.
Working Conditions:
Job Location/Working Conditions
- Patient care setting.
Physical Effort
- Typically sitting at desk or table.
Equipment
- Office equipment.
The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.
Required Qualifications
Education:
Bachelor’s degree or combination of education and/or experience may substitute for minimum education.
Certifications /Professional Licenses:
- Basic Life Support - American Heart Association
- Basic Life Support - American Red Cross
Work Experience:
Clinical Research (2 Years)
Skills:
Not Applicable
Driver's License:
A driver's license is not required for this position.
More About This Job
Required Qualifications:
- Basic Life Support certification must be obtained within one month of hire date.
- Basic Life Support certification (Online BLS certifications, those without a skills assessment component, are not sufficient to meet the BLS requirement).
Preferred Qualifications
Education:
No additional education unless stated elsewhere in the job posting.
Certifications /Professional Licenses:
No additional certification/professional licenses unless stated elsewhere in the job posting.
Work Experience:
No additional work experience unless stated elsewhere in the job posting.
Skills:
Clinical Research, Clinical Study Protocols, Database Management, Research Projects, Spreadsheet Analysis, Statistical Analysis Software (SAS)
Grade
C10
Salary Range
$54,600.00 - $81,900.00 / Annually
The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ.
Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.
Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Benefits Statement
Personal
- Up to 22 days of vacation, 10 recognized holidays, and sick time.
- Competitive health insurance packages with priority appointments and lower copays/coinsurance.
- Take advantage of our free Metro transit U-Pass for eligible employees.
- WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
- Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
- We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
- WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity or shared ancestry, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information. As a federal contractor, the university maintains affirmative action programs to implement its equal employment opportunity policy for individuals with disabilities and protected veterans, in accordance with Section 503 of the Rehabilitation Act of 1973, as amended, and the Vietnam Era Veterans’ Readjustment Assistance Act of 1974 (VEVRAA), as amended.
Location
SAINT LOUIS, MO 63110
Scheduled Hours
40
Position Summary
The Holtz lab is seeking help with a complex observational clinical study at Washington University School of Medicine. The Maternal Offspring Microbiome (MOM) study aims to understand how the infant gut is first populated with bacteria and viruses. We are interested in defining if babies obtain their microbiome from their environment, from the people who care for them, or from their pets.
In this position, you will coordinate a complex clinical research study; serve as a resource to provide comprehensive information to clinical staff by promoting a smooth operation, prepare regulatory compliance and interact with other departments.
You will work closely with other team members and healthcare professionals to recruit and enroll study participants, explain the purpose of study and obtain informed consent from participants, conduct study visits in the hospital and the participant’s home, ensure compliance with protocol guidelines and requirements of the IRB and IACUC, enter data, assist with lab procedures, and perform data analyses.
Preferred applicants are detail orientated, clear communicators, able to provide their own transportation to study visits, curious, enthusiastic, have a flexible schedule (availability needed some weekends, evenings, and early mornings), and have experience with REDCap, Excel, and EPIC.
This position may be responsible for multiple research studies simultaneously.
Primary Duties & Responsibilities:
- Assists in developing plans for research projects and discusses the interpretation of results; collaborates in the preparation of manuscripts for publications and preparation of grant proposals to sponsoring agencies; assists in the preparation of amendments to protocols and/or modifications to study design as appropriate.
- Coordinates the development of forms, questionnaires and the application of research techniques; assists in writing instructional procedure manuals for study progress, data collection and coding; reviews journals, abstracts and scientific literature to keep abreast of new developments and to obtain information regarding previous studies to aid in the planning of new studies.
- Implements and manages all phases of study/protocol; ensures compliance with protocol guidelines and requirements of regulatory agencies; establishes record-keeping systems; makes assessments and determinations of participants’ progress in the study; analyzes, investigates and reports adverse events; makes decisions as when to notify physicians of issues, when to stop participant inclusion and/or to make and/or recommend adjustment of the protocol of particular participants; resolves protocol management issues and recommends corrective action as appropriate; serves as liaison with funding or sponsoring agency.
- Evaluates and interprets collected clinical data as appropriate; prepares oral or written presentations or reports and analyses setting forth progress trends and provides recommendations or conclusions of the same.
- Performs other duties as assigned.
Working Conditions:
Job Location/Working Conditions
- Patient care setting.
Physical Effort
- Typically sitting at desk or table.
Equipment
- Office equipment.
The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.
Required Qualifications
Education:
Bachelor’s degree or combination of education and/or experience may substitute for minimum education.
Certifications /Professional Licenses:
- Basic Life Support - American Heart Association
- Basic Life Support - American Red Cross
Work Experience:
Clinical Research (2 Years)
Skills:
Not Applicable
Driver's License:
A driver's license is not required for this position.
More About This Job
Required Qualifications:
- Basic Life Support certification must be obtained within one month of hire date.
- Basic Life Support certification (Online BLS certifications, those without a skills assessment component, are not sufficient to meet the BLS requirement).
Preferred Qualifications
Education:
No additional education unless stated elsewhere in the job posting.
Certifications /Professional Licenses:
No additional certification/professional licenses unless stated elsewhere in the job posting.
Work Experience:
No additional work experience unless stated elsewhere in the job posting.
Skills:
Clinical Research, Clinical Study Protocols, Database Management, Research Projects, Spreadsheet Analysis, Statistical Analysis Software (SAS)
Grade
C10
Salary Range
$54,600.00 - $81,900.00 / Annually
The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ.
Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.
Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Benefits Statement
Personal
- Up to 22 days of vacation, 10 recognized holidays, and sick time.
- Competitive health insurance packages with priority appointments and lower copays/coinsurance.
- Take advantage of our free Metro transit U-Pass for eligible employees.
- WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
- Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
- We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
- WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity or shared ancestry, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information. As a federal contractor, the university maintains affirmative action programs to implement its equal employment opportunity policy for individuals with disabilities and protected veterans, in accordance with Section 503 of the Rehabilitation Act of 1973, as amended, and the Vietnam Era Veterans’ Readjustment Assistance Act of 1974 (VEVRAA), as amended.
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Find JobsClinical Research Manager Job Market in St. Louis
Who's Hiring
- Washington University in St. Louis63
- Mercy3
- Science 371
- Care Access1
- ObjectiveHealth1
Top Industries Hiring
- Education
Clinical Research Manager Jobs in St. Louis: Frequently Asked Questions
How do I get a clinical research manager job in St. Louis?
St. Louis hiring concentrates around academic medical centers in the Central West End, CROs and biotech firms in the Cortex Innovation Community, and pharmaceutical companies in the western suburbs near Chesterfield. Candidates with experience managing multi-site oncology, cardiovascular, or immunology trials stand out in this market. Building relationships with Washington University Medical Campus and SSM Health research offices gives you a direct line to roles before they are widely posted.
Which companies hire clinical research managers in St. Louis?
Companies currently hiring clinical research managers in St. Louis include Washington University in St. Louis, Mercy, and Science 37, per current listings on Migrate Mate as of November 2026. St. Louis employers tend to be a mix of large academic medical systems, regional contract research organizations, and established pharmaceutical and medical device manufacturers concentrated in and around the metro area.
Are there remote clinical research manager jobs in St. Louis?
Yes, though with limits since many clinical research manager duties involve on-site trial oversight and direct team supervision. About 42% of clinical research manager openings tied to St. Louis are remote or hybrid as of November 2026, with remote options most common in data management, regulatory coordination, and sponsor-facing roles rather than hands-on site monitoring positions.
How can I get a clinical research manager job in St. Louis with little or no experience?
The most realistic path in St. Louis is moving into a clinical research coordinator or senior coordinator role at one of the academic medical centers or regional CROs, then building toward management. Washington University, Saint Louis University Hospital, and Mercy Research are known to develop coordinators internally. Gaining experience with oncology or cardiovascular protocols, which dominate local trial activity, and earning a CCRC or CCRP credential significantly strengthens your candidacy for a first management role.
Which industries hire the most clinical research managers in St. Louis?
St. Louis clinical research manager roles concentrate in Education, based on current listings on Migrate Mate as of November 2026. St. Louis's strong academic medical infrastructure and its legacy as a center for pharmaceutical and agrochemical research have built a dense local ecosystem of sponsors, CROs, and health systems that continuously need experienced trial managers.
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