Software Engineer Jobs at Cadence Design Systems with Visa Sponsorship
Software Engineer jobs at Cadence Design Systems involve building the EDA software and hardware verification tools that power chip design worldwide, working across simulation, RTL, embedded systems, and AI-driven tooling. Cadence has a consistent track record of sponsoring work visas for Software Engineers and supporting long-term permanent residency pathways.
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Get Access To All JobsINTRODUCTION
At Cadence, we hire and develop leaders and innovators who want to make an impact on the world of technology.
ABOUT THE JOB
OpenEye, Cadence Molecular Sciences – a division of Cadence Design Systems – is an industry leader in computational molecular design through rapid, robust, and scalable software, consulting services, and Orion®, the only cloud-native fully integrated software-as-a-service molecular modeling platform. Combining unlimited computation and storage with powerful tools for data sharing, visualization and analysis in a customizable development platform, Orion offers unprecedented capabilities for the advancement of pharmaceuticals, biologics, agrochemicals, and flavors and fragrances.
We are looking for a Computational Chemist/Cheminformatician to join our team of experts in mathematics, computational modeling, and medicinal chemistry. This highly focused team will work together to drive forward technology which leverages OpenEye’s Orion platform to better enable scientists in the pharmaceutical industry working on projects from lead development to clinical candidate selection. This role will require interactions with customers and OpenEye’s scientific and technical teams.
YOUR ROLE AND RESPONSIBILITIES
- Extend OpenEye’s programming toolkits by developing and implementing new and useful scientific and technical features to aid customers in developing bespoke solutions.
- Explore methods for further enhancing OpenEye’s virtual screening platform (including OMEGA, ROCS, FastROCS, ROCS X, OEDocking).
- Apply chemistry/cheminformatics expertise with ML experts to build robust, scalable models to support data-driven decision making.
- Work on retrospective and prospective projects both internally and with collaborators to validate methodologies.
- Work with Orion project team to further optimize compound design workflows in Orion.
BASIC QUALIFICATIONS
- PhD (or equivalent experience) in computational chemistry, chemistry, cheminformatics, or related field with 0 – 3 years relevant experience
- Knowledge of some traditional computational chemistry approaches such as docking, virtual screening, molecular modeling, etc.
- Programming expertise, ideally in c++ and/or python preferably with experience using AI coding agents
- Experience in or desire to learn about the pharmaceutical industry
- Strong desire to find practical solutions to challenging problems
- Demonstrated ability to work both as part of a team and independently
PREFERRED QUALIFICATIONS
- Experience with OpenEye software/toolkits
- Experience with synthetically accessible, pharmaceutically relevant generative chemistry
COMPENSATION
- The annual salary range for Massachusetts is $101,500 to $188,500. You may also be eligible to receive incentive compensation: bonus, equity, and benefits. Sales positions generally offer a competitive On Target Earnings (OTE) incentive compensation structure. Please note that the salary range is a guideline and compensation may vary based on factors such as qualifications, skill level, competencies and work location. Our benefits programs include: paid vacation and paid holidays, 401(k) plan with employer match, employee stock purchase plan, a variety of medical, dental and vision plan options, and more.
We’re doing work that matters. Help us solve what others can’t.
INTRODUCTION
At Cadence, we hire and develop leaders and innovators who want to make an impact on the world of technology.
ABOUT THE JOB
OpenEye, Cadence Molecular Sciences – a division of Cadence Design Systems – is an industry leader in computational molecular design through rapid, robust, and scalable software, consulting services, and Orion®, the only cloud-native fully integrated software-as-a-service molecular modeling platform. Combining unlimited computation and storage with powerful tools for data sharing, visualization and analysis in a customizable development platform, Orion offers unprecedented capabilities for the advancement of pharmaceuticals, biologics, agrochemicals, and flavors and fragrances.
We are looking for a Computational Chemist/Cheminformatician to join our team of experts in mathematics, computational modeling, and medicinal chemistry. This highly focused team will work together to drive forward technology which leverages OpenEye’s Orion platform to better enable scientists in the pharmaceutical industry working on projects from lead development to clinical candidate selection. This role will require interactions with customers and OpenEye’s scientific and technical teams.
YOUR ROLE AND RESPONSIBILITIES
- Extend OpenEye’s programming toolkits by developing and implementing new and useful scientific and technical features to aid customers in developing bespoke solutions.
- Explore methods for further enhancing OpenEye’s virtual screening platform (including OMEGA, ROCS, FastROCS, ROCS X, OEDocking).
- Apply chemistry/cheminformatics expertise with ML experts to build robust, scalable models to support data-driven decision making.
- Work on retrospective and prospective projects both internally and with collaborators to validate methodologies.
- Work with Orion project team to further optimize compound design workflows in Orion.
BASIC QUALIFICATIONS
- PhD (or equivalent experience) in computational chemistry, chemistry, cheminformatics, or related field with 0 – 3 years relevant experience
- Knowledge of some traditional computational chemistry approaches such as docking, virtual screening, molecular modeling, etc.
- Programming expertise, ideally in c++ and/or python preferably with experience using AI coding agents
- Experience in or desire to learn about the pharmaceutical industry
- Strong desire to find practical solutions to challenging problems
- Demonstrated ability to work both as part of a team and independently
PREFERRED QUALIFICATIONS
- Experience with OpenEye software/toolkits
- Experience with synthetically accessible, pharmaceutically relevant generative chemistry
COMPENSATION
- The annual salary range for Massachusetts is $101,500 to $188,500. You may also be eligible to receive incentive compensation: bonus, equity, and benefits. Sales positions generally offer a competitive On Target Earnings (OTE) incentive compensation structure. Please note that the salary range is a guideline and compensation may vary based on factors such as qualifications, skill level, competencies and work location. Our benefits programs include: paid vacation and paid holidays, 401(k) plan with employer match, employee stock purchase plan, a variety of medical, dental and vision plan options, and more.
We’re doing work that matters. Help us solve what others can’t.
See all Software Engineer Jobs at Cadence Design Systems
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Get Access To All JobsTips for Finding Software Engineer Jobs at Cadence Design Systems
Align your portfolio to EDA workflows
Cadence hires Software Engineers who understand electronic design automation, hardware simulation, or verification tooling. Before applying, document any experience with RTL, SPICE, or logic simulation, even university projects, so your resume speaks directly to their domain.
Target roles by product line not just title
Cadence's Software Engineer openings span distinct product families: Virtuoso, Xcelium, Palladium, and Allegro. Filtering by product area lets you tailor your application and signals to recruiters that you understand where your skills fit inside the company.
Confirm H-1B sponsorship in your recruiter screen
Cadence sponsors H-1B visas for Software Engineers, but individual hiring managers may not control the process. Ask your recruiter explicitly whether the specific role and team are approved for H-1B sponsorship before investing in technical interviews.
Prepare your credential equivalency documentation early
USCIS specialty occupation requirements mean your degree field must align with the Software Engineer role. If you hold a three-year bachelor's degree or a degree from outside the U.S., get a credential evaluation from a NACES-approved evaluator before your offer stage.
Understand Cadence's Green Card timeline expectations
Cadence sponsors EB-2 and EB-3 Green Cards for Software Engineers, but PERM labor certification adds 12 to 24 months before an I-140 is even filed. Ask during offer negotiation what the typical internal timeline looks like for your role level and country of birth.
Use Migrate Mate to filter verified openings
Cadence posts Software Engineer roles across multiple channels, making it hard to know which have active sponsorship attached. Use Migrate Mate to browse verified Cadence Software Engineer openings filtered by visa type, so you apply only to roles where sponsorship is confirmed.
Frequently Asked Questions
Does Cadence Design Systems sponsor H-1B visas for Software Engineers?
Yes, Cadence Design Systems sponsors H-1B visas for Software Engineers and has done so consistently across recent fiscal years. Because H-1B cap-subject petitions require USCIS lottery selection each April, your timing matters. If you're already in H-1B status with another employer, a transfer to Cadence avoids the lottery entirely and can begin as soon as your offer is accepted.
How do I apply for Software Engineer jobs at Cadence Design Systems?
Applications go through Cadence's careers portal at cadence.com. Before applying, tailor your resume to the specific product line the role supports, whether that's verification, custom IC design, or PCB. You can also browse Cadence Software Engineer openings filtered by visa sponsorship type on Migrate Mate, which makes it easier to identify roles where H-1B or Green Card sponsorship is actively supported.
Which visa types does Cadence Design Systems use for Software Engineers?
Cadence sponsors both nonimmigrant and immigrant visa categories for Software Engineers. H-1B is the primary work visa for new hires requiring sponsorship. For permanent residency, Cadence supports EB-2 and EB-3 Green Card pathways, which involve PERM labor certification filed with the DOL followed by an I-140 immigrant petition with USCIS. Your eligibility for EB-2 versus EB-3 depends on your degree level and the role's requirements.
What qualifications does Cadence Design Systems expect for Software Engineer roles?
Most Cadence Software Engineer roles require a bachelor's degree or higher in computer science, computer engineering, or electrical engineering. Practical experience with C++, Python, or hardware description languages like SystemVerilog is common across postings. For senior roles, Cadence often looks for domain depth in areas such as analog simulation, timing analysis, or hardware-software co-verification rather than general full-stack experience.
How does the H-1B filing timeline affect a Software Engineer offer at Cadence?
If you need a new H-1B and aren't transferring from an existing one, Cadence must register you in the annual USCIS lottery, which opens in March for an October 1 start date. A typical offer-to-start sequence can run six to nine months. Cadence may offer premium processing to expedite USCIS adjudication to 15 business days once selected, though lottery registration itself cannot be expedited.