Exact Sciences Visa Sponsorship Jobs USA
Exact Sciences is a molecular diagnostics company best known for Cologuard, its flagship colorectal cancer screening test. The company has an active visa sponsorship program spanning multiple work visa categories, making it a viable target for international candidates in healthcare, biotech, and medical research roles.
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Help us change lives
At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others.
Position Overview
Staff Bioinformatics and Machine Learning Scientist will lead the development and application of machine learning, statistical modeling, and bioinformatics for next-generation sequencing-based products. This individual will serve as a senior technical leader within Research and Development, working cross-functionally with bioinformatics, assay development, data engineering, software development, quality and product development teams.
The ideal candidate has deep experience analyzing large and complex biological datasets in an industry setting and has demonstrated successful development, validation and deployment of algorithms, statistical and machine learning models using principled and reproducible methodology.
This is a senior individual contributor role requiring strong scientific and technical leadership, and the ability to translate complex genomic data into insights and products.
Essential Duties
Include, but are not limited to, the following:
- Lead the development, evaluation and optimization of machine learning and statistical models for high-dimensional NGS and genomics datasets.
- Design and implement bioinformatics algorithms to support NGS assay development, analytical performance evaluation, quality control, signal detection, classification, or interpretation.
- Collaborate with wet-lab scientists to design experiments, interpret results, identify technical issues, and recommend next steps.
- Apply rigorous statistical and computational methods to evaluate assay performance, reproducibility, robustness, sensitivity, specificity, and sources of technical or biological variation.
- Develop reproducible analysis workflows using modern bioinformatics, data science, and software engineering practices.
- Work within cloud computing environments to process, analyze, and manage large-scale sequencing datasets.
- Present and summarize complex technical findings effectively to cross-functional audiences.
- Serve as subject matter expert for NGS bioinformatics, machine learning and statistical analysis.
- Identify opportunities and build out proof of concept implementations for new state-of-the-art methodology across machine learning, bioinformatics and software engineering.
- Provide guidance and mentorship to junior team members.
- Support development activities within a quality-managed or regulated environment.
- Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
- Support and comply with the company’s Quality Management System policies and procedures.
- Maintain regular and reliable attendance.
- Ability to act with an inclusion mindset and model these behaviors for the organization.
- Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 90% of a typical working day.
- Ability to work on a computer and phone simultaneously.
- Ability to travel 10% of working time away from work location, may include overnight/weekend travel.
Minimum Qualifications
- Ph.D. in bioinformatics, computational biology, computer science, mathematics, or related field; or Master’s degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 4 years of experience in lieu of a Ph.D.; or Bachelor’s degree in bioinformatics, computational biology, computer science, mathematics, or related field plus 6 years of experience in lieu of Ph.D.
- 8+ years of industry or academia experience in bioinformatics.
- 6+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry.
- Demonstrated experience in developing statistical and quantitative methods.
- Deep knowledge and thorough understanding of molecular biology and/or biochemistry and/or next-generation sequencing (NGS) and genomics.
- Demonstrated expertise in product/assay research, design, or development.
- Basic computer skills to include Internet navigation, Email usage, and word processing. Proficient in Microsoft Office to include Excel, Word, and PowerPoint.
- Demonstrated ability to perform the Essential Duties of the position with or without accommodation.
Preferred Qualifications
- 10+ years of experience in medical device/IVD, biotech, life science or pharmaceutical industry.
- Deep expertise in NGS bioinformatics and genomic data analysis.
- Practical experience effectively leveraging AI in regulated environments.
- Experience with modern cloud-based MLOps systems.
- Experience developing and applying advanced linear and non-linear statistical learning methods on complex datasets, including but not limited to supervised and unsupervised machine learning techniques.
- Familiarity with applying deep learning to high dimensional data.
- Previous experience as a project lead for a team of scientists.
- 2+ years of direct people leadership and management experience.
- Experience in a pharmaceutical or biotech manufacturing environment, preferably in a GMP and/or ISO environment.
- Previous industry experience in product development or technical support.
- Previous experience working in molecular diagnostics.
Salary Range:
California Ranges: $154,400.00 - $231,600.00
The annual base salary shown is for this position located in US - CA - La Jolla on a full-time basis. In addition, this position is bonus eligible.
Exact Sciences is proud to offer an employee experience that includes paid time off (including days for vacation, holidays, volunteering, and personal time), paid leave for parents and caregivers, a retirement savings plan, wellness support, and health benefits including medical, prescription drug, dental, and vision coverage. Learn more about our benefits.
Our success relies on the experiences and perspectives of a diverse team, and Exact Sciences fosters a culture where all employees can develop personally and professionally with a sense of respect and belonging. If you require an accommodation, please contact us here.
Not ready to apply? Join our Talent Community to stay updated on the latest news and opportunities at Exact Sciences.
We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to disability, protected veteran status, and any other status protected by applicable local, state, or federal law.
To view the Right to Work, E-Verify Employer, and Pay Transparency notices and Federal, Federal Contractor, and State employment law posters, visit our compliance hub. The documents summarize important details of the law and provide key points that you have a right to know.
Job Roles at Exact Sciences
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Get Access To All JobsTips for Finding Exact Sciences Visa Sponsorship Jobs USA
Target roles in molecular diagnostics and oncology R&D
Exact Sciences centers its business on cancer detection technology. Scientists, bioinformaticians, and clinical researchers in oncology-adjacent fields are well-positioned, these are the roles most likely to attract sponsorship consideration from a diagnostics-focused employer.
Understand which visa types Exact Sciences supports
Exact Sciences sponsors H-1B, TN, J-1, F-1 OPT, and F-1 CPT visas, as well as Green Card pathways. If you hold or are approaching the end of OPT, confirming early that a role includes Green Card sponsorship reduces long-term uncertainty significantly.
Apply before OPT or CPT authorization runs short
Exact Sciences participates in F-1 OPT and CPT programs, which gives students a viable entry point. Factor in hiring lead times in healthcare and start your search with enough runway to complete onboarding before your authorization period expires.
Search for roles verified as sponsorship-eligible
Not every posting at a sponsoring company will actually include sponsorship. Migrate Mate surfaces verified sponsors so you can filter by real sponsorship history and focus your effort on roles where international candidates are genuinely considered.
Lean into Exact Sciences's commercial and regulatory functions
Beyond the lab, diagnostics companies need regulatory affairs specialists, health economists, and medical science liaisons. These professional roles in healthcare services can qualify as specialty occupations for H-1B purposes, broadening your options beyond pure research tracks.
Position your application around patient impact
Exact Sciences's mission is saving lives through early cancer detection. Candidates who connect their experience to clinical outcomes or diagnostic accuracy, not just technical skills, tend to resonate more strongly in interviews at mission-driven healthcare organizations like this one.
Frequently Asked Questions
Does Exact Sciences sponsor H-1B visas?
Yes, Exact Sciences sponsors H-1B visas. The company has a consistent track record of H-1B filings, particularly for roles in research, data science, bioinformatics, and clinical development. If you're targeting Exact Sciences on an H-1B, focus on specialty occupation roles where your degree directly aligns with the position requirements, as this is central to H-1B eligibility.
What visa types does Exact Sciences sponsor?
Exact Sciences sponsors a range of visa types including H-1B, TN visa, J-1 visa, F-1 OPT, and F-1 CPT for work authorization, and supports Green Card sponsorship through EB-2 and EB-3 pathways for longer-term immigration goals. This breadth makes the company a practical option for international candidates at different stages of their U.S. immigration journey.
Which departments or roles at Exact Sciences are most likely to receive visa sponsorship?
Sponsorship at Exact Sciences is most concentrated in technical and scientific functions, roles in molecular biology, bioinformatics, clinical research, regulatory affairs, and data science are common candidates. Commercial functions such as medical affairs and health economics may also qualify. Roles requiring a specific degree field tied directly to job duties are typically the strongest fits for H-1B specialty occupation classification.
How do I find visa-sponsored job openings at Exact Sciences?
The most reliable approach is to use Migrate Mate, which aggregates job listings from companies with verified sponsorship histories and lets you filter specifically for employers like Exact Sciences. This saves time compared to manually scanning postings and guessing whether sponsorship is available. Look for roles in R&D, clinical operations, and data science, where Exact Sciences has historically been most active with international hires.
How do I time my application to Exact Sciences around H-1B cap deadlines?
H-1B cap-subject petitions must be filed by April 1 for an October 1 start date, which means you need a job offer in hand by mid-March at the latest. Target Exact Sciences roles in late 2025 or early 2026 if you need cap sponsorship for the next fiscal year. If you're already on OPT or CPT, you may be able to start sooner through a cap-exempt or concurrent filing arrangement, confirm this with the employer early in the process.