Sales Jobs at Guardant Health with Visa Sponsorship
Guardant Health hires for Sales roles across oncology diagnostics, where field-based positions require deep clinical knowledge and a consultative approach to selling. The company has a track record of sponsoring work visas for qualified Sales professionals, making it a realistic target if you need employer sponsorship.
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Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer.
The Director of Sales Operations for Guardant Health’s Screening Business Unit will lead the operational backbone that enables our field teams to scale early cancer detection solutions. This role is a people leader leading sales planning and enablement teams and is responsible for driving sales productivity and operational excellence across a rapidly growing commercial organization. The ideal candidate understands the complexity of healthcare sales and brings a data-driven, process-oriented mindset to support national screening adoption. The Director will serve as a strategic partner to Shield Sales Leadership, Enterprise/IDN teams, Marketing, Market Access, and Finance to scale adoption across complex health systems and community-based primary care.
Key Responsibilities
Primary Care Commercial Strategy & Business Planning
- Partner with SHIELD Sales Leadership to develop annual and multi-year commercial operating plans.
- Build structured regional and territory-level business planning frameworks.
- Establish disciplined operating rhythms including QBRs, territory reviews, and performance dashboards.
Territory Design
- Design and optimize territories to maximize productivity and geographic efficiency.
- Continuously reassess territory alignment as SHIELD adoption scales.
Incentive Compensation
- Lead the incentive compensation team to shape incentive compensation design, quota setting, and territory planning in alignment with broader business goals.
- Ensure incentive structures reinforce call plan priorities and strategic account focus.
- Partner with Finance to ensure accurate commission processing and governance.
Call Plan Strategy, Adherence & Routing Optimization
- Develop data-driven call plans aligned with practice opportunity and usage.
- Define clear KPIs for activity frequency, quality, and adherence.
- Implement routing optimization strategies to improve field productivity and reduce drive-time inefficiencies.
- Monitor activity-to-adoption conversion metrics.
- Establish governance processes ensuring CRM discipline and accurate activity capture.
- Partner with Sales Leadership to reinforce execution accountability.
Sales Process & Analytics
- Build dashboards and performance metrics to track funnel conversion, PCP penetration, account expansion, and rep productivity.
- Support launch planning through market opportunity analysis, KPI development, and early performance tracking for new product or territory expansions.
IDN & Health System Strategy and Analytics
- Build dashboards measuring IDN penetration, cross-clinic adoption, and screening uptake trends.
- Support coordinated rollout strategies across large health systems.
- Partner with Enterprise Sales and Market Access to align EMR integration, contracting, and population health initiatives.
Systems, Tools & Data Quality
- Oversee Salesforce and related commercial systems for the Screening business.
- Drive enhancements that support lead routing, account segmentation, targeting, and data cleanliness.
- Evaluate new tools that improve screening rep efficiency, field insights, and customer engagement.
Enablement & Field Readiness
- Partner closely with Sales Enablement to support onboarding, training, territory ramp, and methodology adoption for Screening reps.
- Ensure reps have up-to-date messaging, collateral, and operational playbooks aligned with the screening product strategy.
Cross-Functional Coordination
- Work with Marketing on lead management, demand-generation analytics, and campaign influence.
- Partner with Medical Affairs, Market Access, and Product teams to ensure field visibility into coverage changes, evidence updates, and product roadmap shifts.
- Collaborate with Finance on forecasting alignment and compensation design.
Team Leadership
- Build, lead, and develop a high-performing Sales Operations team supporting Screening analytics, systems, and processes.
- Drive a culture of accountability, continuous improvement, and operational excellence.
Qualifications
- 12+ years in Sales Operations, Revenue Operations, or Commercial Operations, ideally in diagnostics, med-tech, or healthcare.
- 5+ years People Management experience.
- Experience supporting field teams in complex, multi-stakeholder healthcare environments (PCPs, health systems, IDNs, payers).
- Deep expertise in Salesforce and BI tools; strong analytical and modeling skills.
- Demonstrated ability to scale processes in high-growth or innovation-driven commercial organizations.
- Excellent communication skills and comfort engaging cross-functionally at all levels.
Hybrid Work Model:
This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need.
Primary Location: Palo Alto, CA
Primary Location Base Pay Range: $185,400 - $254,950
Other US Location(s) Base Pay Range: $185,400 - $254,950
If the role is performed in Colorado, the pay range for this job is: $185,400 - $254,950
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com.
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

Company Description
Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer.
The Director of Sales Operations for Guardant Health’s Screening Business Unit will lead the operational backbone that enables our field teams to scale early cancer detection solutions. This role is a people leader leading sales planning and enablement teams and is responsible for driving sales productivity and operational excellence across a rapidly growing commercial organization. The ideal candidate understands the complexity of healthcare sales and brings a data-driven, process-oriented mindset to support national screening adoption. The Director will serve as a strategic partner to Shield Sales Leadership, Enterprise/IDN teams, Marketing, Market Access, and Finance to scale adoption across complex health systems and community-based primary care.
Key Responsibilities
Primary Care Commercial Strategy & Business Planning
- Partner with SHIELD Sales Leadership to develop annual and multi-year commercial operating plans.
- Build structured regional and territory-level business planning frameworks.
- Establish disciplined operating rhythms including QBRs, territory reviews, and performance dashboards.
Territory Design
- Design and optimize territories to maximize productivity and geographic efficiency.
- Continuously reassess territory alignment as SHIELD adoption scales.
Incentive Compensation
- Lead the incentive compensation team to shape incentive compensation design, quota setting, and territory planning in alignment with broader business goals.
- Ensure incentive structures reinforce call plan priorities and strategic account focus.
- Partner with Finance to ensure accurate commission processing and governance.
Call Plan Strategy, Adherence & Routing Optimization
- Develop data-driven call plans aligned with practice opportunity and usage.
- Define clear KPIs for activity frequency, quality, and adherence.
- Implement routing optimization strategies to improve field productivity and reduce drive-time inefficiencies.
- Monitor activity-to-adoption conversion metrics.
- Establish governance processes ensuring CRM discipline and accurate activity capture.
- Partner with Sales Leadership to reinforce execution accountability.
Sales Process & Analytics
- Build dashboards and performance metrics to track funnel conversion, PCP penetration, account expansion, and rep productivity.
- Support launch planning through market opportunity analysis, KPI development, and early performance tracking for new product or territory expansions.
IDN & Health System Strategy and Analytics
- Build dashboards measuring IDN penetration, cross-clinic adoption, and screening uptake trends.
- Support coordinated rollout strategies across large health systems.
- Partner with Enterprise Sales and Market Access to align EMR integration, contracting, and population health initiatives.
Systems, Tools & Data Quality
- Oversee Salesforce and related commercial systems for the Screening business.
- Drive enhancements that support lead routing, account segmentation, targeting, and data cleanliness.
- Evaluate new tools that improve screening rep efficiency, field insights, and customer engagement.
Enablement & Field Readiness
- Partner closely with Sales Enablement to support onboarding, training, territory ramp, and methodology adoption for Screening reps.
- Ensure reps have up-to-date messaging, collateral, and operational playbooks aligned with the screening product strategy.
Cross-Functional Coordination
- Work with Marketing on lead management, demand-generation analytics, and campaign influence.
- Partner with Medical Affairs, Market Access, and Product teams to ensure field visibility into coverage changes, evidence updates, and product roadmap shifts.
- Collaborate with Finance on forecasting alignment and compensation design.
Team Leadership
- Build, lead, and develop a high-performing Sales Operations team supporting Screening analytics, systems, and processes.
- Drive a culture of accountability, continuous improvement, and operational excellence.
Qualifications
- 12+ years in Sales Operations, Revenue Operations, or Commercial Operations, ideally in diagnostics, med-tech, or healthcare.
- 5+ years People Management experience.
- Experience supporting field teams in complex, multi-stakeholder healthcare environments (PCPs, health systems, IDNs, payers).
- Deep expertise in Salesforce and BI tools; strong analytical and modeling skills.
- Demonstrated ability to scale processes in high-growth or innovation-driven commercial organizations.
- Excellent communication skills and comfort engaging cross-functionally at all levels.
Hybrid Work Model:
This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need.
Primary Location: Palo Alto, CA
Primary Location Base Pay Range: $185,400 - $254,950
Other US Location(s) Base Pay Range: $185,400 - $254,950
If the role is performed in Colorado, the pay range for this job is: $185,400 - $254,950
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com.
A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.
See all 28+ Sales at Guardant Health jobs
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Get Access To All JobsTips for Finding Sales Jobs at Guardant Health Jobs
Align your background to oncology diagnostics sales
Guardant Health's Sales roles center on liquid biopsy and genomic testing products sold into oncology practices and health systems. Highlight any experience selling diagnostic tools, lab services, or precision medicine products when building your resume and cover letter.
Target territories with active open headcount
Guardant Health posts Sales openings by geographic territory. Applying to a region with multiple open roles signals active hiring velocity, which typically means faster offer cycles and a recruiter with budget already approved, reducing sponsorship negotiation friction.
Raise sponsorship needs after a strong first screen
In healthcare diagnostics sales, recruiters screen heavily on clinical selling experience before discussing logistics. Lead with your quota attainment and relevant product knowledge in the first interview, then address your visa situation once the hiring manager is invested in your candidacy.
Use Migrate Mate to filter verified sponsorship openings
Search Guardant Health's Sales listings on Migrate Mate to surface roles where sponsorship has been confirmed. This filters out postings where sponsorship eligibility is ambiguous, saving you from advancing through multiple interview rounds before hitting a dead end.
Understand the PERM timeline before accepting an offer
If Guardant Health offers an EB-2 or EB-3 Green Card pathway alongside your H-1B, PERM labor certification with the DOL typically takes one to two years before USCIS even receives the immigrant petition. Factor that into any long-term career planning discussions during the offer stage.
Sales at Guardant Health jobs are hiring across the US. Find yours.
Find Sales at Guardant Health JobsFrequently Asked Questions
Does Guardant Health sponsor H-1B visas for Sales roles?
Yes, Guardant Health sponsors H-1B visas for Sales positions. The company has an established pattern of supporting both new H-1B cap-subject petitions and transfers for candidates already holding H-1B status with another employer. If you're mid-cycle on an existing H-1B, a transfer is generally the faster path since it doesn't require waiting for the October 1 start date.
How do I apply for Sales jobs at Guardant Health?
You can apply directly through Guardant Health's careers page, where Sales openings are listed by territory and role type. Tailoring your application to the specific territory and emphasizing oncology diagnostics or precision medicine sales experience will strengthen your candidacy. You can also browse confirmed sponsorship-eligible Sales openings at Guardant Health through Migrate Mate before submitting your application.
Which visa types does Guardant Health commonly use for Sales roles?
Guardant Health sponsors H-1B visas most frequently for Sales professionals, and also supports TN visas for Canadian and Mexican nationals in qualifying roles. F-1 OPT and CPT are available for students or recent graduates entering the workforce. For longer-term permanent residency, the company has sponsored EB-2 and EB-3 Green Card pathways through the PERM labor certification process.
What qualifications does Guardant Health look for in sponsored Sales candidates?
Guardant Health's Sales roles typically require a bachelor's degree in a life sciences, business, or related field, along with demonstrated experience selling into clinical or hospital settings. Familiarity with oncology workflows, molecular diagnostics, or genomic testing products is a strong differentiator. For H-1B eligibility, your degree must correspond to a specialty occupation, so a science or healthcare-adjacent background strengthens the petition.
How long does the visa sponsorship process take for a Sales role at Guardant Health?
For an H-1B transfer from an existing visa, employment can often begin within weeks of filing. A new cap-subject H-1B petition must be submitted by April 1 for an October 1 start, meaning offers extended after that window require waiting nearly a full year. PERM-based Green Card sponsorship typically adds one to two years through DOL processing before USCIS receives the immigrant petition.
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