CPT Clinical Trial Manager Jobs
Clinical Trial Manager roles sit at the intersection of regulatory compliance, protocol management, and cross-functional team coordination, exactly the kind of integrative work CPT is built for. Your DSO must authorize each position as a direct extension of your clinical research, public health, or life sciences program before you start.
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Get Access To All JobsLocation: US - California - Thousand Oaks
JOB ID: R-242106
LOCATION: US - California - Thousand Oaks
WORK LOCATION TYPE: On Site
DATE POSTED: Apr. 27, 2026
CATEGORY: Scientific
SALARY RANGE: 115,393.45 USD - 156,120.55 USD
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas – Oncology, Inflammation, General Medicine, and Rare Disease – we reach millions of patients each year.
Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.
Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
R-242106 Scientist - Cardiometabolic Disorders
What you will do
Let’s do this. Let’s change the world. In this vital role you will commit to develop a deep understanding of the causal pathogenic mechanisms that drive Obesity and Obesity-Related Comorbidities.
Key Responsibilities:
- Work collaboratively with a team of experts to conduct laboratory experiments to generate robust data supporting the preclinical validation of new therapeutic targets.
- Independently design, execute, and interpret in vitro and ex vivo experiments, including troubleshooting, optimization of assays, data collection, interpretation, biostatistical analysis, and presentation.
- The scope of work will include testing and developing cell lines, conducting gene expression and protein abundance assays, establishing functional assays based on phosphorylation, oligomerization events, or other readouts using high-content imaging or medium throughput plate-based techniques used to support both small and large molecule drug development programs.
- Participation in cross-functional drug development teams as a key intellectual and technical contributor.
- The candidate is expected to be well-versed in the pathophysiology of Obesity and Cardiometabolic Diseases and to be continuously aware of scientific developments in this disease area, with emphasis on preclinical research methodologies and models.
- Present research discoveries to Amgen colleagues and scientific meetings (oral/poster presentations and publish scientific papers in peer-reviewed journals).
- Function optimally in a team-based/collaborative environment as part of a highly integrated team, possess excellent organizational, verbal, and written communication skills and demonstrate ability to produce reliable and reproducible results.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The dedicated laboratory scientist we seek is a professional with these qualifications.
Basic Qualifications:
- Doctorate degree
OR - Master’s degree and 2 years of experience in Cardiovascular research or related discipline
OR - Bachelor’s degree and 4 years of experience in Cardiovascular research or related discipline
Preferred Qualifications:
- A PhD in a relevant field with 0-2 years of experience.
- A MS in a relevant field with 5+ years of experience.
- Ideal candidates should have broad experience working with models of cardiometabolic disease, both in vitro and in vivo.
- Ability to perform in vitro assays to dissect the mechanism of action of therapeutic molecules in cardiac myocytes, fibroblasts, adipocytes, endothelial cells, and other relevant cardiometabolic cell types.
- Ideal candidates should have in vitro experience with cultured cell lines, siRNA transfection techniques, western blotting, quantitative PCR techniques, RNA/DNA isolation, laboratory automation, high content imaging technology, and fluorescence microscopy.
- Demonstrated excellence working in a team environment and possessing good laboratory documentation skills.
What you can expect from us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
and make a lasting impact with the Amgen team.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Location: US - California - Thousand Oaks
JOB ID: R-242106
LOCATION: US - California - Thousand Oaks
WORK LOCATION TYPE: On Site
DATE POSTED: Apr. 27, 2026
CATEGORY: Scientific
SALARY RANGE: 115,393.45 USD - 156,120.55 USD
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas – Oncology, Inflammation, General Medicine, and Rare Disease – we reach millions of patients each year.
Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.
Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
R-242106 Scientist - Cardiometabolic Disorders
What you will do
Let’s do this. Let’s change the world. In this vital role you will commit to develop a deep understanding of the causal pathogenic mechanisms that drive Obesity and Obesity-Related Comorbidities.
Key Responsibilities:
- Work collaboratively with a team of experts to conduct laboratory experiments to generate robust data supporting the preclinical validation of new therapeutic targets.
- Independently design, execute, and interpret in vitro and ex vivo experiments, including troubleshooting, optimization of assays, data collection, interpretation, biostatistical analysis, and presentation.
- The scope of work will include testing and developing cell lines, conducting gene expression and protein abundance assays, establishing functional assays based on phosphorylation, oligomerization events, or other readouts using high-content imaging or medium throughput plate-based techniques used to support both small and large molecule drug development programs.
- Participation in cross-functional drug development teams as a key intellectual and technical contributor.
- The candidate is expected to be well-versed in the pathophysiology of Obesity and Cardiometabolic Diseases and to be continuously aware of scientific developments in this disease area, with emphasis on preclinical research methodologies and models.
- Present research discoveries to Amgen colleagues and scientific meetings (oral/poster presentations and publish scientific papers in peer-reviewed journals).
- Function optimally in a team-based/collaborative environment as part of a highly integrated team, possess excellent organizational, verbal, and written communication skills and demonstrate ability to produce reliable and reproducible results.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The dedicated laboratory scientist we seek is a professional with these qualifications.
Basic Qualifications:
- Doctorate degree
OR - Master’s degree and 2 years of experience in Cardiovascular research or related discipline
OR - Bachelor’s degree and 4 years of experience in Cardiovascular research or related discipline
Preferred Qualifications:
- A PhD in a relevant field with 0-2 years of experience.
- A MS in a relevant field with 5+ years of experience.
- Ideal candidates should have broad experience working with models of cardiometabolic disease, both in vitro and in vivo.
- Ability to perform in vitro assays to dissect the mechanism of action of therapeutic molecules in cardiac myocytes, fibroblasts, adipocytes, endothelial cells, and other relevant cardiometabolic cell types.
- Ideal candidates should have in vitro experience with cultured cell lines, siRNA transfection techniques, western blotting, quantitative PCR techniques, RNA/DNA isolation, laboratory automation, high content imaging technology, and fluorescence microscopy.
- Demonstrated excellence working in a team environment and possessing good laboratory documentation skills.
What you can expect from us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
and make a lasting impact with the Amgen team.
Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
See all 33+ Clinical Trial Manager jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Clinical Trial Manager roles.
Get Access To All JobsClinical Trial Manager CPT: Frequently Asked Questions
Does a Clinical Trial Manager role qualify for CPT authorization?
Yes, if the position is an integral part of your enrolled curriculum. Your DSO will evaluate whether the responsibilities, protocol oversight, site management, regulatory submissions, align with your degree program in clinical research, public health, or a related field. Generic project management roles at CROs may not qualify if the connection to your coursework isn't documented clearly.
Can I work full-time as a Clinical Trial Manager on CPT?
Full-time CPT (20 or more hours per week) is allowed but affects your OPT eligibility. If you accumulate 12 months or more of full-time CPT, you lose access to standard OPT after graduation. Part-time CPT has no such cap. Many students in clinical research programs split their authorization into part-time semesters to preserve their post-graduation options.
How do I find Clinical Trial Manager employers who accept CPT?
Search Migrate Mate to browse Clinical Trial Manager openings filtered by sponsorship history. Contract research organizations, pharmaceutical manufacturers, and academic medical centers are the most active CPT employers in this field. Targeting companies with existing regulatory infrastructure means they're more likely to have HR teams familiar with F-1 work authorization requirements.
What documents does my employer need to support my CPT application?
Your employer must provide a written offer letter that includes your job title, start and end dates, work location, and whether the role is part-time or full-time. Some DSO offices also require a brief description of how the position connects to your academic program. Get this letter before your DSO deadline, since they can't issue the updated I-20 without it.
Does CPT authorization affect my path to H-1B sponsorship after graduation?
CPT itself doesn't disqualify you from H-1B sponsorship, but the employer must separately file an H-1B petition after your graduation, typically using OPT as the bridge status. Clinical Trial Manager is a specialty occupation under USCIS criteria, so the role type isn't a barrier. The timing depends on your graduation date, the H-1B cap lottery cycle, and whether your employer has cap-exempt status.
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