Data Science Lead Jobs in Massachusetts

Data Science Lead jobs in Massachusetts are in strong demand, concentrated in life sciences, financial services, and technology sectors, with openings at every level from emerging team leads through senior principal roles. Boston, Cambridge, and the Route 128 corridor anchor most of the hiring, where employers like Biogen, Fidelity Investments, and MathWorks maintain significant data and analytics teams. The most sought-after specializations in Massachusetts are machine learning engineering, clinical and biomedical data science, and quantitative modeling for financial applications. Find a role that fits below and apply directly.

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Overview

Open roles27
Top employerCollegium Pharmaceutical
Top cityBoston, MA
Cities hiring10
Work type50% On-site
Top industryInsurance

Showing 5 of 27+ Data Science Lead jobs

Nova Biomedical
Sr. Manager, Data Science & Analytics
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Nova Biomedical
New 14h ago
Sr. Manager, Data Science & Analytics
Nova Biomedical
Waltham, Massachusetts
Business Development
Customer Success
Program Management
Project Management
$210k - $250k/yr
Hybrid
501-1,000

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Aspen Technology
Data Science Intern - Summer 2027 - Bedford, MA
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Aspen Technology
Added 2d ago
Data Science Intern - Summer 2027 - Bedford, MA
Aspen Technology
Bedford, Massachusetts
Business Operations
Product Management
Project Management
$40 - $50/hr
Hybrid
Master's degree in computer science

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XPO
Lead Scientist, Data Science (Pricing Optimization) - Hybrid
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XPO
Added 2d ago
Lead Scientist, Data Science (Pricing Optimization) - Hybrid
XPO
Boston, Massachusetts
Business Operations
Revenue Operations & Enablement
Sales
Hybrid
Doctoral degree in statistics
10,000+

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Collegium Pharmaceutical, Inc.
Senior Analyst, Data Science & Sales Analytics
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Collegium Pharmaceutical, Inc.
Added 2d ago
Senior Analyst, Data Science & Sales Analytics
Collegium Pharmaceutical, Inc.
Boston, Massachusetts
Business Analysis
Compensation & Benefits
Human Resources (HR) — Generalist
$113k - $146k/yr
On-Site
Bachelor's degree in statistics
201-500

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Collegium Pharmaceutical, Inc.
Senior Analyst, Data Science and Business Analytics
We won't show you this job again
Collegium Pharmaceutical, Inc.
Added 2d ago
Senior Analyst, Data Science and Business Analytics
Collegium Pharmaceutical, Inc.
Boston, Massachusetts
Business Analysis
Compensation & Benefits
Human Resources (HR) — Generalist
$113k - $146k/yr
On-Site
Bachelor's degree in statistics
201-500

Have you applied for this role?

See All 27 Data Science Lead Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

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Data Science Lead Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Cambridge
4 jobs
Waltham
3 jobs
Stoughton
2 jobs
Lowell
1 job
Natick
1 job
Bedford
1 job
Watertown
1 job
New Bedford
1 job

Data Science Lead Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

Collegium Pharmaceutical
Collegium Pharmaceutical4 open roles
XPO
XPO2 open roles
Novartis
Novartis2 open roles

Top Industries Hiring

  • Insurance
  • Medical Devices
  • Technology & Software
  • Biotechnology & Pharmaceuticals

What Massachusetts Employers Look For

The qualifications that appear most often in data science lead jobs across Massachusetts.

  • Bachelor's or master's degree in computer science, statistics, or a quantitative field
  • Five or more years of experience in data science or a closely related analytical discipline
  • Demonstrated experience leading and mentoring a team of data scientists or analysts
  • Proficiency in Python, R, and SQL with deep knowledge of machine learning frameworks
  • Experience translating complex analytical findings into strategy for non-technical stakeholders
  • Familiarity with cloud platforms such as AWS, Azure, or Google Cloud in production environments

Data Science Lead Jobs in Massachusetts: Frequently Asked Questions

How do you become a data science lead in Massachusetts?

There is no state-issued license required to work as a data science lead in Massachusetts. Most employers expect a master's degree or higher in data science, statistics, applied mathematics, or computer science, with several years of hands-on modeling experience before moving into a leadership role. Massachusetts has a dense graduate-program ecosystem at institutions like MIT, Harvard, and Northeastern, and completing advanced coursework or a capstone project in a domain relevant to life sciences or fintech gives candidates a concrete edge in the local market.

How much do data science leads make in Massachusetts?

Data science leads in Massachusetts earn a median of about $131,750 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $81,030 for the lowest 10% to over $206,220 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire data science leads in Massachusetts?

Employers hiring data science leads in Massachusetts right now include Collegium Pharmaceutical, XPO, and Novartis, based on current listings on Migrate Mate as of September 2026. Massachusetts's concentration of biotech, asset management, and enterprise software firms means openings are consistently distributed across multiple industries rather than being tied to a single sector.

Which Massachusetts cities have the most data science lead jobs?

Boston, Cambridge, and Waltham are the Massachusetts cities with the most data science lead openings right now. Boston and Cambridge dominate because of the density of hospitals, universities, and financial institutions headquartered there, while suburban Route 128 corridor hubs like Waltham and Burlington draw significant volume from the technology and pharmaceutical employers concentrated along that corridor.

Are there remote data science lead jobs in Massachusetts?

Yes, and more than most fields. About 50% of data science lead openings tied to Massachusetts are remote or hybrid as of September 2026, reflecting how much of the core work involves modeling, code review, and stakeholder presentations that translate naturally to distributed settings. The portions of the role most amenable to full remote work are individual contributor modeling tasks, while team mentorship and cross-functional strategy sessions are more likely to require periodic in-person presence.

How can I get hired as a data science lead in Massachusetts with little or no experience?

The most realistic entry path is moving laterally from a senior data scientist or machine learning engineer role into an informal team lead position at a Massachusetts employer. Biogen, Liberty Mutual, and several Boston-area health systems regularly post associate data scientist and data analyst roles designed for candidates early in their careers, and strong performance in those positions leads to lead-level responsibilities within a few years. Building a public portfolio of end-to-end machine learning projects, particularly in biomedical data or financial modeling given Massachusetts's industry mix, makes a candidate noticeably stronger in a competitive applicant pool.

Where can I find and apply to data science lead jobs in Massachusetts?

You can find and apply to data science lead jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings updated in real time. Find roles that fit your experience and apply directly to each one without needing to create a profile or sign up first.

See All 27 Data Science Lead Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Data Science Lead Jobs