Green Card DevOps Consultant Jobs
DevOps Consultant roles qualify for EB-2 or EB-3 green card sponsorship through the PERM labor certification process, which requires your employer to document that no qualified U.S. worker is available for the position. Sponsorship leads to lawful permanent residency, giving you the right to work for any U.S. employer without restrictions.
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Get Access To All JobsINTRODUCTION
Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicle™ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
ROLE AND RESPONSIBILITIES:
Leads Development Sciences Operations to support nonclinical and clinical development programs across Toxicology, Pathology, DMPK, Clinical, Pharmacology, Biomarkers, and Bioanalytical functions. Oversees operational execution, external partnerships, and study delivery to ensure quality, compliance, and timelines. Manages team members and vendors while driving cross-functional coordination and operational consistency across programs.
Key Accountabilities/Core Job Responsibilities:
- Lead Development Sciences Operations activities across programs, including oversight of staff, vendors, and study execution
- Manage and develop direct reports, including goal setting, performance management, and coaching
- Serve as primary operational interface with CROs, establishing workflows, expectations, and oversight
- Manage vendor selection and contracting (RFIs, SOWs, budgets, change orders) in partnership with Legal and Finance
- Oversee execution of nonclinical and clinical studies, ensuring timelines, quality, and compliance (GLP, GCP, GCLP)
- Coordinate cross-functional activities with Discovery, Development Sciences, and Clinical Operations to support program delivery
- Establish and track study timelines, risks, and deliverables to meet program objectives
- Ensure data quality, reporting, and integration into internal systems to support decision-making
- Ensure compliance with study protocols, regulatory requirements (e.g., IACUC), and internal SOPs
- Drive operational improvements, standardization, and efficiency across Development Sciences activities
BASIC QUALIFICATIONS:
- Typically requires a Bachelor’s degree in Pharmacology, Toxicology, Pharmaceutical Sciences, or related field (advanced degree preferred)
- Typically requires 9+ years of biopharmaceutical experience with progressive responsibility in development sciences or operations and management experience
- Demonstrates experience managing direct reports and leading work through others in a matrixed environment
- Demonstrates working knowledge of nonclinical and clinical development operations, including Toxicology, DMPK, and Bioanalytical workflows
- Demonstrates experience managing CROs, vendors, and outsourced study execution
- Demonstrates ability to manage programs, including timelines, risks, budgets, and cross-functional coordination
- Demonstrates strong communication, problem-solving, and organizational skills in a fast-paced environment
COMPENSATION
- Salary Range: $171,000.00 to $223,000.00. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits.
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
INTRODUCTION
Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicle™ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
ROLE AND RESPONSIBILITIES:
Leads Development Sciences Operations to support nonclinical and clinical development programs across Toxicology, Pathology, DMPK, Clinical, Pharmacology, Biomarkers, and Bioanalytical functions. Oversees operational execution, external partnerships, and study delivery to ensure quality, compliance, and timelines. Manages team members and vendors while driving cross-functional coordination and operational consistency across programs.
Key Accountabilities/Core Job Responsibilities:
- Lead Development Sciences Operations activities across programs, including oversight of staff, vendors, and study execution
- Manage and develop direct reports, including goal setting, performance management, and coaching
- Serve as primary operational interface with CROs, establishing workflows, expectations, and oversight
- Manage vendor selection and contracting (RFIs, SOWs, budgets, change orders) in partnership with Legal and Finance
- Oversee execution of nonclinical and clinical studies, ensuring timelines, quality, and compliance (GLP, GCP, GCLP)
- Coordinate cross-functional activities with Discovery, Development Sciences, and Clinical Operations to support program delivery
- Establish and track study timelines, risks, and deliverables to meet program objectives
- Ensure data quality, reporting, and integration into internal systems to support decision-making
- Ensure compliance with study protocols, regulatory requirements (e.g., IACUC), and internal SOPs
- Drive operational improvements, standardization, and efficiency across Development Sciences activities
BASIC QUALIFICATIONS:
- Typically requires a Bachelor’s degree in Pharmacology, Toxicology, Pharmaceutical Sciences, or related field (advanced degree preferred)
- Typically requires 9+ years of biopharmaceutical experience with progressive responsibility in development sciences or operations and management experience
- Demonstrates experience managing direct reports and leading work through others in a matrixed environment
- Demonstrates working knowledge of nonclinical and clinical development operations, including Toxicology, DMPK, and Bioanalytical workflows
- Demonstrates experience managing CROs, vendors, and outsourced study execution
- Demonstrates ability to manage programs, including timelines, risks, budgets, and cross-functional coordination
- Demonstrates strong communication, problem-solving, and organizational skills in a fast-paced environment
COMPENSATION
- Salary Range: $171,000.00 to $223,000.00. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits.
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
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Get Access To All JobsTips for Finding Green Card Sponsorship as a DevOps Consultant
Align your credentials to PERM requirements
PERM requires your employer to define a minimum education and experience requirement for the role. Make sure your degree, certifications, and work history match the job description exactly, since discrepancies between your resume and the PERM application can trigger a DOL audit.
Use O*NET to anchor your specialty
DevOps Consultant maps to multiple SOC codes depending on whether your work is classified as software development, systems architecture, or IT management. Pull the O*NET occupation profile for each relevant code and confirm which one your employer's job duties match before PERM is filed.
Target employers with dedicated immigration programs
PERM sponsorship requires legal resources and a multi-stage recruitment process, so smaller employers often back out mid-process. Prioritize engineering-led companies and technology consultancies that have sponsored green cards before and have in-house or retained immigration counsel.
Search Migrate Mate for verified green card sponsors
Filter your job search to employers with documented EB-2 and EB-3 sponsorship history by using Migrate Mate, which surfaces companies actively sponsoring green cards for DevOps and infrastructure roles, so you're not guessing at willingness during the interview process.
Verify prevailing wage tier before accepting an offer
PERM requires your employer to pay at least the prevailing wage for your SOC code and work location. Use the OFLC Wage Search to look up the wage level yourself before negotiations, since an offer below the Level II or III threshold may force a refile or delay your I-140.
File your I-485 as early as your priority date allows
Nationals of India and China face significant EB-2 and EB-3 backlogs, so your priority date, the date DOL received your PERM application, determines when you can file for adjustment of status. Concurrent filing of your I-140 and I-485 is only available when your priority date is current.
Green Card DevOps Consultant: Frequently Asked Questions
Does a DevOps Consultant role qualify for EB-2 or EB-3 sponsorship?
Most DevOps Consultant positions qualify for EB-2 sponsorship if the employer requires a master's degree or a bachelor's degree plus five years of progressive experience in a specialty such as systems engineering, computer science, or a closely related field. Roles with a bachelor's degree requirement and at least two years of specialized experience typically qualify under EB-3. The employer defines the minimum requirements in the PERM application, and those requirements must genuinely reflect what the job needs, not what you personally hold.
How does green card sponsorship differ from H-1B sponsorship for DevOps roles?
H-1B visa is a temporary nonimmigrant status that requires renewal and ties you to a sponsoring employer. Green card sponsorship through PERM, followed by an I-140 petition and adjustment of status or consular processing, results in lawful permanent residency. PERM requires the employer to conduct a formal DOL-supervised recruitment test to confirm no qualified U.S. worker is available, a step with no equivalent in H-1B. Priority date backlogs also mean approval timelines vary significantly by country of birth, particularly for Indian and Chinese nationals.
What happens to my green card case if I change employers mid-process?
If your I-485 adjustment of status application has been pending for 180 days or more, AC21 job portability lets you move to a new employer in the same or a similar occupation without abandoning your case. Your priority date can also carry over to a new employer's I-140 petition once your original I-140 was approved, even if that employer later withdrew it. These two protections are separate rules, so confirm which applies to your situation with your immigration attorney before resigning.
How do I find DevOps Consultant jobs where the employer will sponsor a green card?
Most job postings don't explicitly state green card sponsorship willingness, which makes identifying the right employers time-consuming. Migrate Mate lists employers with verified EB-2 and EB-3 sponsorship history for DevOps and infrastructure roles, so you can focus your applications on companies that have already committed to the PERM process rather than raising the topic cold in an initial interview.
Can my employer start the PERM process while I'm on an H-1B?
Yes, and starting PERM early is strategically important because it locks in your priority date, which determines your place in the queue for adjustment of status. Employers can file a PERM application on your behalf while you're maintaining H-1B status, and many do so within the first year of employment. The PERM process itself does not affect your H-1B status or your authorization to work while the green card case is pending.