H-1B Visa Artificial Intelligence Scientist Jobs
Artificial Intelligence Scientist roles qualify as H-1B visa specialty occupations under USCIS because they require at least a bachelor's degree in computer science, mathematics, or a closely related field. Most positions fall under SOC code 15-2051, and employers must file a certified LCA with DOL before submitting your I-129 petition.
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PromptBio, established in 2023 in Pleasanton, California, is a biotechnology company dedicated to developing AI-driven workflows that automate the discovery of novel biomarkers from multi-omics data, translating them into clinical diagnostic applications.
ROLE AND RESPONSIBILITIES
We seek a motivated, hands-on AI Scientist to join our interdisciplinary team, focusing on integrating AI solutions within the life sciences domain.
- Design, prototype, and implement cutting-edge autonomous AI agents and multi-agent systems capable of dynamic planning, reasoning, memory management, and self-reflection.
- Develop and integrate core agent components, including planning modules (e.g., Tree-of-Thought, CoT-based planners), tool-use interfaces, and persistent long-term memory/retrieval mechanisms (RAG).
- Develop high-quality, production-ready code in Python/Go for integrating LLMs and other foundational models into functional agent architectures.
- Build and maintain scalable agent infrastructure using frameworks like LangChain ensuring seamless integration with cloud services (AWS preferred).
- Conduct rigorous testing, evaluation, and optimization of agent performance on complex, real-world tasks.
- Work closely with the engineering team to define agent use cases and translate research prototypes into deployable product features that deliver business value.
BASIC QUALIFICATIONS
- Minimum of 2-3 years of industry experience with demonstrated practical experience building and implementing LLM-based agents (e.g., using tool-calling, external memory, and multi-step reasoning).
- Strong understanding of key agentic concepts: Memory (Short-Term/Long-Term), Planning, Tool Use, and Self-Reflection/Evaluation.
- Hands-on experience with agentic automation/frameworks (e.g., LangChain, ReAct, etc.), vector databases (e.g., Qdrant), and infrastructure services (e.g., Bedrock AgentCore).
- Fluency with software engineering best practices, including testing, code reviews, version control (e.g., Git), and containerization.
- Knowledge of AI ethics and safety principles, particularly as they apply to autonomous decision-making systems.
- Knowledge of bioinformatics data analysis will be a significant plus.
- Ph.D. in AI, Machine Learning, Statistics, Bioinformatics or a related field.
PREFERRED QUALIFICATIONS
- Entrepreneurial mindset with comfort in ambiguous, fast-paced environments.
- Proactive, results-oriented, and driven with a "get things done" mindset.
- Strong problem-solving skills and adaptability to evolving project requirements.
- Collaborative team player who thrives in dynamic environments.
BENEFITS
- Financial security through competitive compensation, incentives, and retirement plan.
- Healthcare and well-being programs including competitive medical, dental, and vision benefits.
- Generous paid time-off including vacation, sick time, holidays, and discretionary winter shutdown.
- 401(k) retirement savings with a generous company match.
- Other comprehensive voluntary benefits include but are not limited to pet insurance, life insurance, employee assistance program (EAP), discount programs, and many more.
- We continue to optimize our benefits & wellness programs as we grow our organization to make sure they meet our diverse workforce needs.
- Hybrid work opportunities.
LOCATION
Location: Pleasanton, CA, USA
Employment: Full-time
INTRODUCTION
PromptBio, established in 2023 in Pleasanton, California, is a biotechnology company dedicated to developing AI-driven workflows that automate the discovery of novel biomarkers from multi-omics data, translating them into clinical diagnostic applications.
ROLE AND RESPONSIBILITIES
We seek a motivated, hands-on AI Scientist to join our interdisciplinary team, focusing on integrating AI solutions within the life sciences domain.
- Design, prototype, and implement cutting-edge autonomous AI agents and multi-agent systems capable of dynamic planning, reasoning, memory management, and self-reflection.
- Develop and integrate core agent components, including planning modules (e.g., Tree-of-Thought, CoT-based planners), tool-use interfaces, and persistent long-term memory/retrieval mechanisms (RAG).
- Develop high-quality, production-ready code in Python/Go for integrating LLMs and other foundational models into functional agent architectures.
- Build and maintain scalable agent infrastructure using frameworks like LangChain ensuring seamless integration with cloud services (AWS preferred).
- Conduct rigorous testing, evaluation, and optimization of agent performance on complex, real-world tasks.
- Work closely with the engineering team to define agent use cases and translate research prototypes into deployable product features that deliver business value.
BASIC QUALIFICATIONS
- Minimum of 2-3 years of industry experience with demonstrated practical experience building and implementing LLM-based agents (e.g., using tool-calling, external memory, and multi-step reasoning).
- Strong understanding of key agentic concepts: Memory (Short-Term/Long-Term), Planning, Tool Use, and Self-Reflection/Evaluation.
- Hands-on experience with agentic automation/frameworks (e.g., LangChain, ReAct, etc.), vector databases (e.g., Qdrant), and infrastructure services (e.g., Bedrock AgentCore).
- Fluency with software engineering best practices, including testing, code reviews, version control (e.g., Git), and containerization.
- Knowledge of AI ethics and safety principles, particularly as they apply to autonomous decision-making systems.
- Knowledge of bioinformatics data analysis will be a significant plus.
- Ph.D. in AI, Machine Learning, Statistics, Bioinformatics or a related field.
PREFERRED QUALIFICATIONS
- Entrepreneurial mindset with comfort in ambiguous, fast-paced environments.
- Proactive, results-oriented, and driven with a "get things done" mindset.
- Strong problem-solving skills and adaptability to evolving project requirements.
- Collaborative team player who thrives in dynamic environments.
BENEFITS
- Financial security through competitive compensation, incentives, and retirement plan.
- Healthcare and well-being programs including competitive medical, dental, and vision benefits.
- Generous paid time-off including vacation, sick time, holidays, and discretionary winter shutdown.
- 401(k) retirement savings with a generous company match.
- Other comprehensive voluntary benefits include but are not limited to pet insurance, life insurance, employee assistance program (EAP), discount programs, and many more.
- We continue to optimize our benefits & wellness programs as we grow our organization to make sure they meet our diverse workforce needs.
- Hybrid work opportunities.
LOCATION
Location: Pleasanton, CA, USA
Employment: Full-time
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Get Access To All JobsTips for Finding H-1B Visa Sponsorship as an Artificial Intelligence Scientist
Map your degree to the role
USCIS scrutinizes whether your degree field directly relates to AI science work. A computer science or statistics degree maps cleanly. A business degree with no quantitative focus can trigger an RFE, so document any coursework or credentials that bridge the gap.
Search LCA filings for AI roles
Use Migrate Mate to filter employers by H-1B LCA filing history for AI Scientist positions. DOL disclosure data shows which companies have certified wages and filed for this specific SOC code, cutting your search time significantly.
Verify the prevailing wage tier before negotiating
Your employer's LCA must certify a wage at or above the DOL prevailing wage for your location and experience level. Run the OFLC Wage Search for SOC 15-2051 before you negotiate an offer so you know the floor and can flag any underpayment risk early.
Check whether the role qualifies for cap exemption
AI Scientist positions at universities, nonprofit research institutions, and certain government research labs are cap-exempt, meaning your employer can file year-round without waiting for the April lottery. Confirm the employer's cap-exempt status before counting on that timeline.
Document your publication and patent record now
Peer-reviewed publications, patents, and conference presentations strengthen specialty occupation evidence for AI roles, especially when your job duties push into research territory. Compile a full list with dates and venues before the employer starts the I-129 package.
Clarify premium processing eligibility upfront
USCIS offers premium processing on I-129 petitions, which guarantees a 15-business-day adjudication decision. Confirm with your employer whether they'll elect premium processing before your current work authorization expires, particularly if you're transitioning from OPT.
H-1B Visa Artificial Intelligence Scientist: Frequently Asked Questions
Does an Artificial Intelligence Scientist role qualify as an H-1B specialty occupation?
Yes. USCIS classifies AI Scientist positions as specialty occupations because they require at least a bachelor's degree in a specific technical field such as computer science, applied mathematics, or statistics. The O*NET profile for this occupation confirms a graduate-level education requirement, which supports the specialty occupation determination in the I-129 petition.
Which employers sponsor H-1B visas for AI Scientist positions?
Technology companies, pharmaceutical firms, financial institutions, and university research labs are among the most active H-1B sponsors for AI Scientist roles. DOL LCA disclosure data shows which specific employers have certified wages for this SOC code. Migrate Mate surfaces that filing history by employer so you can target companies with a demonstrated sponsorship track record rather than guessing.
Can I transfer my H-1B to a new AI Scientist role without losing my priority date?
Yes. Under AC21 portability, you can transfer your H-1B to a new employer in the same or a similar occupational classification once your I-140 has been approved for 180 days or more. AI Scientist roles typically fall under the same SOC code, so a transfer to a comparable position at a new employer generally satisfies the same-or-similar requirement.
How does the H-1B lottery affect AI Scientist job seekers?
Cap-subject H-1B petitions enter the annual lottery, with 65,000 regular-cap slots and 20,000 additional slots reserved for U.S. master's degree holders. AI Scientists with a U.S. master's or PhD are eligible for the advanced-degree exemption pool, which improves selection odds. Positions at cap-exempt institutions such as universities bypass the lottery entirely.
What happens to my H-1B status if my AI Scientist role shifts significantly toward research?
If your core duties change materially, your employer may need to file an amended I-129 petition to reflect the new role description. USCIS expects the approved petition to accurately describe your actual work. Significant shifts in job duties, location, or employer entity without an amended filing can create status compliance issues, so flag changes to your employer's immigration counsel promptly.