Head Of Operations Jobs in San Francisco, CA
Head Of Operations jobs in San Francisco are in strong demand, concentrated in SoMa, the Financial District, and Mission Bay across technology, healthcare, and professional services. Employers hiring right now include Genentech, Ramp, and Visa. See the openings below and apply to the ones that match your experience.
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About the Role
A small, early-stage AI company serving manufacturers is seeking a Head of Operations / COO to work closely with the founders. You will own day-to-day business operations and help build scalable customer delivery and supply chain processes.
What You'll Do
Lead end-to-end operations, including customer onboarding, order execution, supplier and carrier coordination, and issue resolution.
Build processes, metrics, and playbooks that help a lean team serve more manufacturers.
Partner with engineering to identify operational workflows that AI agents should automate.
Manage supplier and freight operations, vendor relationships, and service quality.
Hire and lead the operations team as the business grows.
Work with the founders on planning, finance, and company priorities.
What We're Looking For
Six to ten years of relevant experience, including senior operations leadership as a Head of Operations, COO, VP or Director of Operations, or in a similar role.
Hands-on experience in supply chain, procurement, logistics, or manufacturing operations.
Experience at an early-stage startup or on a small team, with the ability to build processes from the ground up and stay hands-on.
Strong numerical, systems, and process-design skills.
Experience in CPG, food, supplements, cosmetics, chemicals, or related manufacturing, or in freight brokerage or 3PL operations, is helpful.
Past founder or early startup experience is a plus.
Location
On-site in San Francisco, California, five days per week. Candidates may relocate within the United States.
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Find Head Of Operations JobsHead Of Operations Job Market in San Francisco
Who's Hiring
Top Industries Hiring
- Banking & Financial Services
Head Of Operations Jobs in San Francisco: Frequently Asked Questions
How do I get a head of operations job in San Francisco?
The strongest path into a head of operations role in San Francisco runs through the city's technology and venture-backed startup sectors, where operational leadership is a consistent hiring priority. Companies concentrated in SoMa, Mission Bay, and the Financial District look for candidates with cross-functional experience managing teams, vendor relationships, and process improvements. A background in scaling operations at a growth-stage company gives you a real edge in this market.
Which companies hire head of operationss in San Francisco?
Employers hiring head of operationss in San Francisco right now include Genentech, Ramp, and Visa, based on current listings on Migrate Mate as of November 2026. San Francisco's hiring landscape skews toward technology companies, healthcare organizations, and professional services firms that need senior operational leaders to manage complex, high-growth environments.
Are there remote head of operations jobs in San Francisco?
Yes, though remote availability depends on the role's scope, since heads of operations who oversee physical locations, facilities, or in-person teams are typically required on-site. About 89% of head of operations openings tied to San Francisco are remote or hybrid as of November 2026, skewing toward companies in technology and professional services. Strategic and analytical responsibilities tend to be the most flexible for remote work in this market.
How can I get a head of operations job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is through an operations coordinator or operations associate role at a startup or mid-size technology company in SoMa or Mission Bay, where smaller teams create faster paths to broader responsibility. Employers at this stage often value demonstrated project ownership, process documentation skills, and the ability to work across teams over years of formal experience. Building exposure through operations programs at local high-growth companies can accelerate the transition significantly.
Which industries hire the most head of operationss in San Francisco?
Most head of operations openings in San Francisco sit in Banking & Financial Services, per current listings on Migrate Mate as of November 2026. San Francisco's concentration of technology headquarters, life sciences companies near Mission Bay, and financial services firms in the Financial District drives consistent demand for senior operational leadership across those sectors.
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