Information Systems Security Officer Jobs

Information Systems Security Officer jobs are open across defense contracting, federal agencies, healthcare, and financial services, from junior analyst to senior ISSO and program lead, with specializations in risk management frameworks, authorization and accreditation, and continuous monitoring. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles161+
Top stateMaryland
Top employerLockheed Martin
Top cityAnnapolis Junction, MD
Work type91% On-site
Top industryAerospace

Showing 5 of 161+ Information Systems Security Officer jobs

JT4
Information Systems Security Officer - China Lake
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JT4
Added 1d ago
Information Systems Security Officer - China Lake
JT4
Ridgecrest, California
Business Operations
Consulting & Professional Services
Healthcare Administration
Quality Assurance & Testing (QA Testing)
$86k - $101k/yr
On-Site
Associate's degree in information technology
1,001-5,000

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Torch Technologies
Information Systems Security Officer (ISSO)
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Torch Technologies
Added 1d ago
Information Systems Security Officer (ISSO)
Torch Technologies
Huntsville, Alabama
Compliance & Risk
Cybersecurity
Security & Protective Services
Bachelor's degree
1,001-5,000

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V
Information Systems Security Officer (ISSO) / Unit Software License Manager (USLM)
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V
Added 1d ago
Information Systems Security Officer (ISSO) / Unit Software License Manager (USLM)
Vision Information Technology Consultants LLC
Randolph AFB, Texas
Compliance & Legal
Compliance & Risk
Consulting & Professional Services

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CALIBRE Systems
Senior Information Systems Security Officer (ISSO)/Information Systems Security Manager (ISSM)
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CALIBRE Systems
Added 1d ago
Senior Information Systems Security Officer (ISSO)/Information Systems Security Manager (ISSM)
CALIBRE Systems
Aberdeen, Maryland
Account Management
Customer Success
Sales
Master's degree in cybersecurity
501-1,000

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KBR
Information Systems Security Officer (ISSO)
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KBR
Added 1d ago
Information Systems Security Officer (ISSO)
KBR
Beavercreek, Ohio
Customer Service & Support
Customer Support
IT Support
Technical Program Management
Bachelor's degree
10,000+

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Top Cities Hiring Information Systems Security Officers

Explore information systems security officer openings in the cities hiring most right now.

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Information Systems Security Officer Job Market

Who's Hiring

  • Lockheed Martin
    Lockheed Martin11
  • AMERICAN SYSTEMS
    AMERICAN SYSTEMS10
  • General Dynamics Information Technology
    General Dynamics Information Technology6
  • MTSI
    MTSI5
  • Raytheon
    Raytheon5

Top Industries Hiring

  • Aerospace & Defense
  • Technology & Software
  • Consulting & Professional Services
  • Telecommunications
  • Biotechnology & Pharmaceuticals

What Employers Look For

The qualifications that appear most often in information systems security officer jobs.

  • Active Secret or Top Secret security clearance required by most federal and defense employers
  • Hands-on experience with NIST Risk Management Framework and system authorization packages
  • Certifications such as CISSP, CAP, CompTIA Security+, or CISM strongly preferred or required
  • Experience developing and maintaining system security plans, POAMs, and security assessment reports
  • Familiarity with SIEM tools, vulnerability scanning platforms, and continuous monitoring processes
  • Bachelor's degree in information security, computer science, or a related technical discipline

Tips for Your Information Systems Security Officer Job Search

Tailor your resume to RMF language

Most ISSO postings screen for Risk Management Framework terminology. Mirror the exact language from each job listing, including control families, system boundaries, and authorization package components, so your resume clears automated screening before a human reads it.

List every active certification clearly

Certifications like CISSP, CAP, Security+, and CISM are often listed as hard filters. Put them in a dedicated section near the top of your resume with exact credential names, issuing bodies, and expiration or renewal dates so reviewers can verify them instantly.

Apply early to roles that fit

Migrate Mate lists information systems security officer openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Filter for clearance level upfront

Many ISSO postings require an active Secret or Top Secret clearance and will not consider applicants in the adjudication process. Search by clearance level before applying so you spend your time on roles where your current eligibility is a match.

Prepare a live ATO package walkthrough

Hiring panels frequently ask you to walk through an authorization to operate package you managed. Prepare a concise narrative covering the system boundary definition, control selection rationale, risk acceptance decisions, and any findings you remediated before authorization was granted.

Negotiate on clearance sponsorship, not just salary

If a role requires a clearance you don't currently hold, ask during the offer stage whether the employer will sponsor and fund the investigation. This is a standard negotiating point in this field and can significantly affect total employment value.

Information Systems Security Officer Jobs: Frequently Asked Questions

Which companies are hiring the most information systems security officers?

The companies hiring the most information systems security officers right now include Lockheed Martin, AMERICAN SYSTEMS, and General Dynamics Information Technology, with the largest share of openings in Maryland, District of Columbia, and Virginia, based on current listings on Migrate Mate as of July 2026. Defense contractors and federal agencies consistently account for a high share of active postings in this field.

How many information systems security officer jobs are remote?

About 9% of information systems security officer openings are fully remote or hybrid as of July 2026, though clearance requirements limit full remote availability for many positions. Roles focused on policy development, continuous monitoring, and compliance documentation tend to offer the most location flexibility compared to positions requiring on-site system access.

How do you become an information systems security officer?

Start by earning a bachelor's degree in information security, cybersecurity, or computer science, then pursue entry-level security analyst or IT roles to build hands-on experience. Obtain a foundational certification like CompTIA Security+ early, then work toward CISSP or CAP as you gain experience with NIST frameworks, system authorization packages, and risk management processes in a federal or defense environment.

Can you get hired as an information systems security officer with little experience?

Yes, some employers hire candidates into junior or associate ISSO roles if you hold a relevant certification and can demonstrate familiarity with NIST RMF concepts. Internships or entry-level positions in IT security, help desk, or network administration provide the foundational exposure hiring managers look for, and obtaining a security clearance early significantly expands your available opportunities in this field.

What does the information systems security officer interview process look like?

The process typically includes an initial phone screen focused on clearance eligibility and certification verification, followed by a technical interview where you walk through past authorization packages, POAMs, or audit findings you managed. A final panel interview often involves scenario-based questions on risk acceptance decisions, incident response procedures, and how you handle conflicts between security requirements and operational timelines.

Where can I find and apply to information systems security officer jobs?

You can find and apply to information systems security officer jobs on Migrate Mate, which lists current openings from across the United States. Search for roles that match your clearance level, certifications, and experience, then apply directly to each listing that fits your background.

See All 161+ Information Systems Security Officer Jobs

Find roles that match your experience and apply in just a few clicks.

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