Information Systems Security Officer Jobs
Information Systems Security Officer jobs are open across defense contracting, federal agencies, healthcare, and financial services, from junior analyst to senior ISSO and program lead, with specializations in risk management frameworks, authorization and accreditation, and continuous monitoring. Scan the live roles below and apply to whichever ones fit.
Find JobsOverview
Showing 5 of 194+ Information Systems Security Officer jobs
The Opportunity:
Join CACI as a Systems Engineer with an Information Systems Security Officer (ISSO) focus, where you will play a key role in ensuring the security, integrity, and reliability of mission‑critical systems. You will apply systems engineering principles across the full system lifecycle—from concept through retirement—while partnering closely with stakeholders, technical teams, and senior leadership. This role offers the chance to directly influence secure system design, support cloud modernization efforts, and guide programs through key security authorization activities.
Responsibilities
Serve as the primary liaison ensuring clear communication and alignment across teams.
Act as the security coordinator for all assigned products, including STE/STN activities, SSP reauthorization, and accessibility (508) compliance.
Collaborate with the cloud architecture team to support cloud migration and integration efforts.
Provide systems engineering expertise across all ISO/IEC 15288 process areas and maintain accountability for the technical quality, integrity, and completeness of associated deliverables.
Communicate effectively with sponsors, overseers, and senior executives to address engineering considerations and resolve technical issues.
Qualifications
Required:
Active TS/SCI with Polygraph.
20+ years of experience as a Systems Engineer supporting programs of similar scope, type, and complexity.
Proven ability to plan, lead, and execute systems engineering efforts.
Bachelor’s degree in Systems Engineering, Computer Science, Information Systems, Engineering Science, Engineering Management, or related field.
May substitute 5 additional years of systems engineering experience in lieu of a bachelor’s degree.)
Desired:
Experience working in hybrid SE/ISSO roles
Familiarity with cloud technologies and cloud migration initiatives
Strong communication skills with experience interfacing with senior government or program stakeholders
Knowledge of ISO/IEC 15288 processes and lifecycle management best practices.
What You Can Expect:
A culture of integrity.
At CACI, we place character and innovation at the center of everything we do. As a valued team member, you’ll be part of a high-performing group dedicated to our customer’s missions and driven by a higher purpose – to ensure the safety of our nation.
An environment of trust.
CACI values the unique contributions that every employee brings to our company and our customers - every day. You’ll have the autonomy to take the time you need through a unique flexible time off benefit and have access to robust learning resources to make your ambitions a reality.
A focus on continuous growth.
Together, we will advance our nation's most critical missions, build on our lengthy track record of business success, and find opportunities to break new ground — in your career and in our legacy.
Pay Range :
There are a host of factors that can influence final salary including, but not limited to, geographic location, Federal Government contract labor categories and contract wage rates, relevant prior work experience, specific skills and competencies, education, and certifications. Our employees value the flexibility at CACI that allows them to balance quality work and their personal lives. We offer competitive compensation, benefits and learning and development opportunities. Our broad and competitive mix of benefits options is designed to support and protect employees and their families. At CACI, you will receive comprehensive benefits such as; healthcare, wellness, financial, retirement, family support, continuing education, and time off benefits.
The proposed salary range for this position is:
$131,800 - $290,000The Opportunity:
Join CACI as a Systems Engineer with an Information Systems Security Officer (ISSO) focus, where you will play a key role in ensuring the security, integrity, and reliability of mission‑critical systems. You will apply systems engineering principles across the full system lifecycle—from concept through retirement—while partnering closely with stakeholders, technical teams, and senior leadership. This role offers the chance to directly influence secure system design, support cloud modernization efforts, and guide programs through key security authorization activities.
Responsibilities
Serve as the primary liaison ensuring clear communication and alignment across teams.
Act as the security coordinator for all assigned products, including STE/STN activities, SSP reauthorization, and accessibility (508) compliance.
Collaborate with the cloud architecture team to support cloud migration and integration efforts.
Provide systems engineering expertise across all ISO/IEC 15288 process areas and maintain accountability for the technical quality, integrity, and completeness of associated deliverables.
Communicate effectively with sponsors, overseers, and senior executives to address engineering considerations and resolve technical issues.
Qualifications
Required:
Active TS/SCI with Polygraph.
20+ years of experience as a Systems Engineer supporting programs of similar scope, type, and complexity.
Proven ability to plan, lead, and execute systems engineering efforts.
Bachelor’s degree in Systems Engineering, Computer Science, Information Systems, Engineering Science, Engineering Management, or related field.
May substitute 5 additional years of systems engineering experience in lieu of a bachelor’s degree.)
Desired:
Experience working in hybrid SE/ISSO roles
Familiarity with cloud technologies and cloud migration initiatives
Strong communication skills with experience interfacing with senior government or program stakeholders
Knowledge of ISO/IEC 15288 processes and lifecycle management best practices.
What You Can Expect:
A culture of integrity.
At CACI, we place character and innovation at the center of everything we do. As a valued team member, you’ll be part of a high-performing group dedicated to our customer’s missions and driven by a higher purpose – to ensure the safety of our nation.
An environment of trust.
CACI values the unique contributions that every employee brings to our company and our customers - every day. You’ll have the autonomy to take the time you need through a unique flexible time off benefit and have access to robust learning resources to make your ambitions a reality.
A focus on continuous growth.
Together, we will advance our nation's most critical missions, build on our lengthy track record of business success, and find opportunities to break new ground — in your career and in our legacy.
Pay Range :
There are a host of factors that can influence final salary including, but not limited to, geographic location, Federal Government contract labor categories and contract wage rates, relevant prior work experience, specific skills and competencies, education, and certifications. Our employees value the flexibility at CACI that allows them to balance quality work and their personal lives. We offer competitive compensation, benefits and learning and development opportunities. Our broad and competitive mix of benefits options is designed to support and protect employees and their families. At CACI, you will receive comprehensive benefits such as; healthcare, wellness, financial, retirement, family support, continuing education, and time off benefits.
The proposed salary range for this position is:
$131,800 - $290,000Information Systems Security Officer Jobs by Experience Level
Top Cities Hiring Information Systems Security Officers
Explore information systems security officer openings in the cities hiring most right now.
See All 194+ Information Systems Security Officer Jobs
Find roles that match your experience and apply in just a few clicks.
Find JobsInformation Systems Security Officer Job Market
Who's Hiring
- AMERICAN SYSTEMS10
- General Dynamics Information Technology9
- Leidos6
- Peraton6
- BAE Systems USA4
Top Industries Hiring
- Technology & Software
- Consulting & Professional Services
What Employers Look For
The qualifications that appear most often in information systems security officer jobs.
- Active Secret or Top Secret security clearance required by most federal and defense employers
- Hands-on experience with NIST Risk Management Framework and system authorization packages
- Certifications such as CISSP, CAP, CompTIA Security+, or CISM strongly preferred or required
- Experience developing and maintaining system security plans, POAMs, and security assessment reports
- Familiarity with SIEM tools, vulnerability scanning platforms, and continuous monitoring processes
- Bachelor's degree in information security, computer science, or a related technical discipline
Tips for Your Information Systems Security Officer Job Search
Tailor your resume to RMF language
Most ISSO postings screen for Risk Management Framework terminology. Mirror the exact language from each job listing, including control families, system boundaries, and authorization package components, so your resume clears automated screening before a human reads it.
List every active certification clearly
Certifications like CISSP, CAP, Security+, and CISM are often listed as hard filters. Put them in a dedicated section near the top of your resume with exact credential names, issuing bodies, and expiration or renewal dates so reviewers can verify them instantly.
Apply early to roles that fit
Migrate Mate lists information systems security officer openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Filter for clearance level upfront
Many ISSO postings require an active Secret or Top Secret clearance and will not consider applicants in the adjudication process. Search by clearance level before applying so you spend your time on roles where your current eligibility is a match.
Prepare a live ATO package walkthrough
Hiring panels frequently ask you to walk through an authorization to operate package you managed. Prepare a concise narrative covering the system boundary definition, control selection rationale, risk acceptance decisions, and any findings you remediated before authorization was granted.
Negotiate on clearance sponsorship, not just salary
If a role requires a clearance you don't currently hold, ask during the offer stage whether the employer will sponsor and fund the investigation. This is a standard negotiating point in this field and can significantly affect total employment value.
Information Systems Security Officer Jobs: Frequently Asked Questions
Which companies are hiring the most information systems security officers?
The companies hiring the most information systems security officers right now include AMERICAN SYSTEMS, General Dynamics Information Technology, and Leidos, with the largest share of openings in Maryland, Virginia, and District of Columbia, based on current listings on Migrate Mate as of September 2026. Defense contractors and federal agencies consistently account for a high share of active postings in this field.
How many information systems security officer jobs are remote?
About 31% of information systems security officer openings are fully remote or hybrid as of September 2026, though clearance requirements limit full remote availability for many positions. Roles focused on policy development, continuous monitoring, and compliance documentation tend to offer the most location flexibility compared to positions requiring on-site system access.
How do you become an information systems security officer?
Start by earning a bachelor's degree in information security, cybersecurity, or computer science, then pursue entry-level security analyst or IT roles to build hands-on experience. Obtain a foundational certification like CompTIA Security+ early, then work toward CISSP or CAP as you gain experience with NIST frameworks, system authorization packages, and risk management processes in a federal or defense environment.
Can you get hired as an information systems security officer with little experience?
Yes, some employers hire candidates into junior or associate ISSO roles if you hold a relevant certification and can demonstrate familiarity with NIST RMF concepts. Internships or entry-level positions in IT security, help desk, or network administration provide the foundational exposure hiring managers look for, and obtaining a security clearance early significantly expands your available opportunities in this field.
What does the information systems security officer interview process look like?
The process typically includes an initial phone screen focused on clearance eligibility and certification verification, followed by a technical interview where you walk through past authorization packages, POAMs, or audit findings you managed. A final panel interview often involves scenario-based questions on risk acceptance decisions, incident response procedures, and how you handle conflicts between security requirements and operational timelines.
Where can I find and apply to information systems security officer jobs?
You can find and apply to information systems security officer jobs on Migrate Mate, which lists current openings from across the United States. Search for roles that match your clearance level, certifications, and experience, then apply directly to each listing that fits your background.
See All 194+ Information Systems Security Officer Jobs
Find roles that match your experience and apply in just a few clicks.
Find Jobs