Lead Information Security Analyst Jobs

Lead Information Security Analyst jobs are open across financial services, healthcare, defense, and technology, from mid-level analyst to senior lead and security architect, with specializations in threat detection, compliance, and incident response. See the openings below and apply to the ones that match your experience.

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Overview

Open roles1,420+
Top stateMaryland
Top employerBooz Allen Hamilton
Top cityAnnapolis Junction, MD
Work type42% Hybrid
Top industryTechnology

Showing 5 of 1,420+ Lead Information Security Analyst jobs

Information System Security Officer (ISSO)
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Information System Security Officer (ISSO)
MTSI
Boston, Massachusetts
Customer Success
Solutions Engineering & Architecture
Technical Program Management
Bachelor's degree
1,001-5,000

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Sr Manager Information Security
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Sr Manager Information Security
DXC Technology
Washington, Washington DC
Health & Safety (EHS & OHS)
Compliance & Legal
Data Science & Analytics
Security & Protective Services
Compliance & Risk
$166k - $307k/yr
On-Site
Bachelor's
10,000+

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Manager Information Security
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Manager Information Security
DXC Technology
Washington, Washington DC
Cybersecurity
Cloud & DevOps
Technical Product & Program Management
Security Engineering
DevOps
Technical Program Management
$132k - $246k/yr
On-Site
Bachelor's
10,000+

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Information Systems Security Manager
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New 1h ago
Information Systems Security Manager
M.C. Dean, Inc.
Tysons, Virginia
Project Management
Solutions Engineering & Architecture
Technical Program Management
$150k - $188k/yr
Bachelor's degree in information technology
5,001-10,000

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Manager Information Security
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Manager Information Security
DXC Technology
Washington, District of Columbia
Project Management
Software Engineering
Technical Product & Program Management
$132k - $246k/yr
Bachelor's degree in engineering
10,000+

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Lead Information Security Analyst Job Market

Who's Hiring

  • Booz Allen Hamilton33
  • Base-2 Solutions27
  • Lockheed Martin26
  • Walmart20
  • MANTECH18

Top Industries Hiring

  • Technology & Software24
  • Education13
  • Consulting & Professional Services11
  • Healthcare & Medical Services7
  • Banking & Financial Services6

What Employers Look For

The qualifications that appear most often in lead information security analyst jobs.

  • Five or more years of hands-on information security experience, including at least two years in a lead or senior capacity
  • Active CISSP, CISM, or equivalent certification recognized by the employer
  • Demonstrated experience with SIEM platforms, endpoint detection tools, and vulnerability management systems
  • Deep knowledge of regulatory frameworks such as NIST, ISO 27001, PCI DSS, or HIPAA
  • Experience leading incident response investigations and producing executive-level security reports
  • Bachelor's degree in computer science, cybersecurity, information systems, or a closely related field

Tips for Your Lead Information Security Analyst Job Search

Tailor your resume to the threat model

Hiring managers for lead information security analyst roles scan for the specific threat landscapes you've defended against. Call out whether your experience covers cloud-native environments, OT networks, or regulated industries like HIPAA or FedRAMP, not just generic security skills.

Lead with certifications that matter here

CISSP, CISM, and GIAC certifications carry real weight for lead-level roles. Put them in your resume header, not buried in a skills section, so they clear ATS filters and catch a reviewer's eye before they read your experience.

Apply early to roles that fit

Migrate Mate lists lead information security analyst openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Filter for roles that match your clearance level

Many lead information security analyst postings in defense and federal contracting require an active Secret or Top Secret clearance. Applying to those without the right clearance wastes both parties' time, so filter by clearance requirement before you read the full description.

Prepare a threat-response narrative for interviews

Interviewers at the lead level routinely ask you to walk through a real incident you managed end to end. Prepare a structured account that covers detection, containment, root cause analysis, and what you changed afterward, with enough technical detail to hold up under follow-up questions.

Negotiate total comp, not just base salary

Lead information security analyst offers often include training budgets, certification reimbursement, and on-call premiums that vary widely. Ask HR to break out each component before you evaluate the offer so you're comparing like for like across positions.

Lead Information Security Analyst Jobs: Frequently Asked Questions

Which companies are hiring the most lead information security analysts?

Booz Allen Hamilton, Base-2 Solutions, and Lockheed Martin are hiring the most lead information security analysts right now, with openings concentrated in Maryland, Virginia, and District of Columbia, based on current listings on Migrate Mate as of November 2026. Financial services, defense contractors, and large health systems tend to post the highest volume of lead-level security roles.

How many lead information security analyst jobs are remote?

About 60% of lead information security analyst openings are fully remote or hybrid as of November 2026, with remote availability highest in cloud security, security engineering, and GRC-focused roles. Positions tied to on-premises infrastructure, data centers, or classified government environments are more likely to require an in-office or on-site presence.

How do you become a lead information security analyst?

Start with a foundation in IT or cybersecurity, then pursue a role as a security analyst to build hands-on experience with SIEM platforms, vulnerability management, and incident response. Earning a certification like CISSP or CISM signals readiness for lead-level work. From there, take on project ownership, mentor junior analysts, and document your contributions to security program improvements to position yourself for a lead title.

Can you get a lead information security analyst job with little experience?

Moving directly into a lead role with little experience is difficult because employers expect you to manage junior staff and own security decisions independently. A realistic path is to build two to three years as a mid-level analyst, specialize in a high-demand area like cloud security or threat intelligence, and demonstrate that you've led projects or cross-functional response efforts before applying to lead-level postings.

What does the lead information security analyst interview process look like?

The process typically runs three to four rounds. An initial recruiter screen is followed by a technical interview covering threat detection, incident response, and your familiarity with relevant frameworks. A panel interview with security leadership often includes a scenario-based exercise where you walk through how you'd handle a live incident or security program gap. Some employers add a final round with the CISO or VP of Security before extending an offer.

Where can I find and apply to lead information security analyst jobs?

You can find and apply to lead information security analyst jobs on Migrate Mate, which lists current openings from across the United States. Search for roles that match your certifications, clearance level, and industry background, then apply directly to each listing that fits.

See All 1,420+ Lead Information Security Analyst Jobs

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