Nurse Practitioner Or Physician Assistant Jobs in Indianapolis, IN
Nurse Practitioner Or Physician Assistant jobs in Indianapolis are in strong demand across hospital systems, urgent care networks, and specialty practices, with the heaviest concentration of openings in the Medical District near IUPUI, the Meridian-Kessler corridor, and Carmel to the north. Employers hiring right now include Indiana University Health, Altea Healthcare, and Concentra. Scan the live roles below and apply to whichever ones fit.
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We are seeking a compassionate and dedicated Nurse Practitioner to join our Pediatric Rheumatology team at Riley Children's Health! Our practice locations serve several communities across the state of Indiana, including Indianapolis, Carmel, South Bend, and Fort Wayne.
Details:
- Full-Time, Day Shift
- 40 hours per week
- No weekends or call
- 15% inpatient & 85% outpatient setting
- Work with an interdisciplinary team of 6 physicians and 7 support staff
- Patient population includes children and adolescents with a wide range of autoimmune, inflammatory and rheumatic conditions. Patients include those with juvenile arthritis, lupus, scleroderma, vasculitis, dermatomyositis, and other complex diseases that affect the joints, muscles, skin, and immune system. The practice also cares for children with rare autoinflammatory and genetic disorders, such as Familial Mediterranean Fever (FMF), TRAPS, NOMID, and recurrent fever syndromes
Responsibilities:
- Conduct comprehensive patient evaluations, including obtaining medical histories, performing physical exams, and assessing disease activity.
- Diagnose, treat, and manage children with rheumatologic and autoimmune conditions under established clinical guidelines and collaborative practice agreements.
- Develop and implement individualized treatment plans, including prescribing medications and monitoring response to therapy.
- Review and interpret laboratory results, imaging studies, and diagnostic tests.
- Provide patient and family education regarding diagnoses, medications, disease management, and treatment expectations.
- Manage medication prior authorizations, specialty medications, and biologic therapies as needed.
- Coordinate care with physicians, nurses, infusion services, therapists, primary care providers, and other specialists.
- Respond to patient calls, messages, and urgent clinical concerns, providing timely assessment and recommendations.
- Monitor patients for medication side effects, disease progression, and treatment effectiveness.
- Document clinical encounters accurately and maintain compliance with regulatory and organizational requirements.
- Participate in quality improvement initiatives, patient safety efforts, and ongoing professional development activities.
Qualifications:
- Master's degree required
- Must be BE or BC
- ACNP, PNP, FNP, or PA certification required
- Experience in pediatric rheumatology preferred
IU Health offers a value-based compensation package that includes: a sign-on forgivable loan, group insurance (health, dental, life, disability), 401k with company match, generous PTO, CME allowance/time off, relocation assistance, and malpractice insurance coverage.
Community Description
Indianapolis, Indiana, the 17th largest U.S. city, is a sophisticated city blending charm and culture with a wonderful balance of business and leisure. Residents of this dynamic city enjoy:
- Leading educational system and top-ranked universities, paired with a diverse population
- Vibrant downtown offering arts, theaters, world-class museums, zoo, concerts and memorials
- Named to U.S. News & World Report's 2023-2024 list of the best places to live in the United States
- Top ranked international airport: "Best Airport in North America" twelve consecutive years
- Ranked by Niche in 2023 as one of the most diverse counties in America, as well as one of the best cities to live in and buy a house in the country
- Historic neighborhoods with surrounding cultural districts and low cost of living
- Outdoor recreation includes golfing, boating and unique parks
- Home of the Colts (NFL), Fever (WNBA), Pacers (NBA), Indians (MiLB), Indianapolis 500 (IndyCar) and the nation's largest half marathon
- Close proximity to Chicago, St. Louis, Louisville, and Cincinnati
Healthcare System/Hospital Description
For 100 years, Riley Hospital for Children has been one of the nation's leading children's hospitals. Each year, Riley Hospital provides compassionate care, support and comfort to more than 300,000 inpatients and outpatients from across Indiana, the nation and the world. Physicians at Riley Hospital provide comprehensive care, from the routine to the most complex, in every field of pediatric medicine and surgery.
Riley Hospital is nationally ranked in 11 specialties as a top children's hospital by U.S. News & World Report, with national rankings in all ten pediatric specialties (including two specialties in the top ten), and is the only nationally ranked children's hospital in Indiana. Part of Indiana University Health, Riley Hospital enjoys a unique partnership with the Indiana University School of Medicine, giving our highly skilled physicians access to innovative treatments using the latest research and technology.
In addition, Riley Hospital is ranked sixth in the nation for NIH Research funding, totaling more than $38.5 million in 2023. The Children's Clinical Research Center, located at Riley Hospital, is one of the largest pediatric research facilities in the country. Riley Hospital also offers one of the nation's largest outpatient care facilities for children.
At Riley Hospital for Children, we are committed to advancing a culture where all people can come together while we work to equitably improve the health of all Hoosiers. Working together, our health system fosters an environment in which differences are respected and valued.
We are an equal opportunity employer. IU Health does not discriminate on the basis of race, color, religion, sex, sexual orientation, age, disability, genetic information, veteran status, national origin, gender identity and/or expression, marital status or any other characteristic protected by federal, state, or local law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Indiana University Health and Indiana University School of Medicine are EOE/AA Employers, M/F/D.
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Find JobsNurse Practitioner Or Physician Assistant Job Market in Indianapolis
Who's Hiring
- Indiana University Health22

- Altea Healthcare3

- Concentra1

- Optimal Care1

- Marathon Health1

Top Industries Hiring
- Healthcare & Medical Services
- Consulting & Professional Services
Nurse Practitioner Or Physician Assistant Jobs in Indianapolis: Frequently Asked Questions
How do I get a nurse practitioner or physician assistant job in Indianapolis?
The strongest hiring activity in Indianapolis is concentrated in large health systems, federally qualified health centers, and the growing network of urgent care and retail clinic operators expanding across Marion County and the surrounding suburbs. Candidates with experience in primary care, emergency medicine, or surgical assist roles tend to move fastest through hiring pipelines here. Tailoring your application to the specific patient population and clinical setting of each Indianapolis employer gives you a clear edge.
Which companies hire nurse practitioner or physician assistants in Indianapolis?
Indianapolis nurse practitioner or physician assistant roles are posted by Indiana University Health, Altea Healthcare, and Concentra and others right now, based on current listings on Migrate Mate as of July 2026. Indianapolis draws a wide mix of large academic health systems, regional multispecialty groups, and national urgent care chains, all of which maintain active rosters of advanced practice provider openings throughout the metro.
Are there remote nurse practitioner or physician assistant jobs in Indianapolis?
Yes, though only for a limited subset of roles, since most nurse practitioner and physician assistant positions require direct patient contact. About 18% of nurse practitioner or physician assistant openings tied to Indianapolis are remote or hybrid as of July 2026, with the most common examples being telehealth urgent care and chronic disease management roles served by Indianapolis-based platforms and payer-affiliated programs.
How can I get a nurse practitioner or physician assistant job in Indianapolis with little or no experience?
The most realistic entry path in Indianapolis is through new-graduate programs and residency fellowships offered by the larger health systems in the Medical District, which are structured specifically to build clinical confidence in advanced practice providers. Community health centers across Marion County also hire new graduates more readily than private specialty groups. Completing clinical rotations with Indianapolis employers during your training and expressing interest in transition-to-practice roles before graduation gives candidates a concrete local advantage.
Which industries hire the most nurse practitioner or physician assistants in Indianapolis?
Most nurse practitioner or physician assistant openings in Indianapolis sit in Healthcare & Medical Services and Consulting & Professional Services, per current listings on Migrate Mate as of July 2026. Indianapolis functions as a regional healthcare hub with a dense concentration of hospital systems, insurance and managed care headquarters, and life sciences employers, all of which sustain consistent advanced practice provider demand across the metro.
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