Nurse Practitioner Or Physician Assistant Jobs in Indianapolis, IN
Nurse Practitioner Or Physician Assistant jobs in Indianapolis are in strong demand across hospital systems, urgent care networks, and specialty practices, with the heaviest concentration of openings in the Medical District near IUPUI, the Meridian-Kessler corridor, and Carmel to the north. Employers hiring right now include Indiana University Health, Optum, and Concentra. Scan the live roles below and apply to whichever ones fit.
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IU Health Medical Group is hiring! We are seeking a Nurse Practitioner or Physician Assistant to join our Orthopedic Trauma team at Methodist Hospital in Indianapolis, IN!
Position Details:
- PRN
- Day Shift
- Shifts available based coverage needs.
- Minimum of 8 hours every 6 weeks
- No call
- 80% Inpatient and 20% Outpatient
- Team includes 8 physicians and 16 advanced practice providers
Key Responsibilities:
- Orthopedic Trauma consults
- Inpatient Rounding
Procedures:
- Fracture/dislocation reductions
- Application of splints
- First Assist in the OR
- Joint Injections
- Joint Aspirations
- Wound Vac application and changes
- Traction Application
Qualifications:
- ACNP, AGNP, FNP or PA certification required
- At least 1 year of APP experience required
- APP experience in orthopedics preferred
Compensation Details:
- We offer a strong compensation model
- Comprehensive benefits package includes group insurance (health, dental, life, disability), 401k with company match, PTO, relocation assistance and occurrence-based malpractice insurance coverage
See how you can thrive, right here at Indiana University Health
Community Description
Indianapolis, Indiana, the 17th largest U.S. city, is a sophisticated city blending charm and culture with a wonderful balance of business and leisure. Residents of this dynamic city enjoy:
- Leading educational system and top-ranked universities, paired with a diverse population
- Vibrant downtown offering arts, theaters, world-class museums, zoo, concerts and memorials
- Named to U.S. News & World Report's 2023-2024 list of the best places to live in the United States
- Top ranked international airport: "Best Airport in North America" twelve consecutive years
- Ranked by Niche in 2023 as one of the most diverse counties in America, as well as one of the best cities to live in and buy a house in the country
- Historic neighborhoods with surrounding cultural districts and low cost of living
- Outdoor recreation includes golfing, boating and unique parks
- Home of the Colts (NFL), Fever (WNBA), Pacers (NBA), Indians (MiLB), Indianapolis 500 (IndyCar) and the nation's largest half marathon
- Close proximity to Chicago, St. Louis, Louisville, and Cincinnati
Healthcare System/Hospital Description
IU Health Methodist Hospital is a regional healthcare leader through its commitment to excellence, accessibility and preeminence. Part of the IU Health Adult Academic Health Center, it is currently ranked by U.S. News & World Report as the top hospital in the state of Indiana, with 13 procedures/conditions rated as high performing.
With 1,000 beds, IU Health Methodist Hospital is a large tertiary referral center with over 130 ICU beds. It serves as the largest trauma center in Indianapolis, as well as a highly subspecialized center for cardiovascular surgery, thoracic surgery, neurosurgery, lung transplantation, and neurocritical care.
IU Health is building a new downtown hospital and campus, which will consolidate operations of the adjacent IU Health Methodist and University Hospitals. Construction for the new hospital is well underway and set to open in late 2027. It will feature three 16-story towers with 864 beds. IU School of Medicine is also constructing a medical education and research building directly east of the new hospital.
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Find JobsNurse Practitioner Or Physician Assistant Job Market in Indianapolis
Who's Hiring
- Indiana University Health99

- Optum4

- Concentra4

- Optimal Care4

- SynergenX Health4

Top Industries Hiring
- Healthcare & Medical Services
- Consulting & Professional Services
Nurse Practitioner Or Physician Assistant Jobs in Indianapolis: Frequently Asked Questions
How do I get a nurse practitioner or physician assistant job in Indianapolis?
The strongest hiring activity in Indianapolis is concentrated in large health systems, federally qualified health centers, and the growing network of urgent care and retail clinic operators expanding across Marion County and the surrounding suburbs. Candidates with experience in primary care, emergency medicine, or surgical assist roles tend to move fastest through hiring pipelines here. Tailoring your application to the specific patient population and clinical setting of each Indianapolis employer gives you a clear edge.
Which companies hire nurse practitioner or physician assistants in Indianapolis?
Indianapolis nurse practitioner or physician assistant roles are posted by Indiana University Health, Optum, and Concentra and others right now, based on current listings on Migrate Mate as of August 2026. Indianapolis draws a wide mix of large academic health systems, regional multispecialty groups, and national urgent care chains, all of which maintain active rosters of advanced practice provider openings throughout the metro.
Are there remote nurse practitioner or physician assistant jobs in Indianapolis?
Yes, though only for a limited subset of roles, since most nurse practitioner and physician assistant positions require direct patient contact. About 28% of nurse practitioner or physician assistant openings tied to Indianapolis are remote or hybrid as of August 2026, with the most common examples being telehealth urgent care and chronic disease management roles served by Indianapolis-based platforms and payer-affiliated programs.
How can I get a nurse practitioner or physician assistant job in Indianapolis with little or no experience?
The most realistic entry path in Indianapolis is through new-graduate programs and residency fellowships offered by the larger health systems in the Medical District, which are structured specifically to build clinical confidence in advanced practice providers. Community health centers across Marion County also hire new graduates more readily than private specialty groups. Completing clinical rotations with Indianapolis employers during your training and expressing interest in transition-to-practice roles before graduation gives candidates a concrete local advantage.
Which industries hire the most nurse practitioner or physician assistants in Indianapolis?
Most nurse practitioner or physician assistant openings in Indianapolis sit in Healthcare & Medical Services and Consulting & Professional Services, per current listings on Migrate Mate as of August 2026. Indianapolis functions as a regional healthcare hub with a dense concentration of hospital systems, insurance and managed care headquarters, and life sciences employers, all of which sustain consistent advanced practice provider demand across the metro.
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