OPT Acute Care Nurse Practitioner Jobs
Acute Care Nurse Practitioner jobs on OPT require STEM-eligible nursing programs and an employer willing to sponsor future H-1B visa status. Healthcare systems frequently sponsor NPs, but NCLEX licensure and state-specific NP certification must be in hand before your start date. Your 12-month OPT clock starts immediately upon authorization.
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City: Phoenix
State: AZ
Remote: No
Department: Hematology
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
Join Mayo Clinic and practice at the top of your license in a fast paced, high impact oncology setting. We are seeking an experienced Acute Care Nurse Practitioner or Physician Assistant to join our Hematology Oncology team.
This unique position blends inpatient and acute ambulatory care so you can keep your skills sharp while caring for complex patients across settings.
What Makes This Role Special
- Hybrid model with inpatient and clinic experience
- Strong APP led practice with high autonomy
- Exposure to advanced and evolving cancer care
- 12-hour shifts that support flexibility
- Collaborative, self-scheduling team
Where You Will Work
This full-time role is based in the Immediate Care Clinic ICC, a hospital-based clinic focused on urgent symptom management for patients receiving cancer treatment.
You will rotate across:
- Hematology Consult Service
- Oncology Consult and Admission Service
- Immediate Care Clinic
The ICC is open 7 days a week, year-round.
What You Will Do
- Evaluate and manage patients with acute oncology needs
- Order and interpret labs, imaging, and diagnostics
- Prescribe medications and develop treatment plans
- Provide education and support to patients and families
- Collaborate with physicians, nursing, and multidisciplinary teams
- Use evidence-based care to manage complex symptoms
Team and Culture
You will join a small, experienced APP team that works closely together and supports one another. This is a highly collaborative environment where your voice matters and your expertise is valued.
During the selection process you may participate in an OnDemand (pre-recorded) interview that you can complete at your convenience. During the OnDemand interview, a question will appear on your screen, and you will have time to consider each question before responding. You will have the opportunity to re-record your answer to each question – Mayo Clinic will only see the final recording. The complete interview will be reviewed by a Mayo Clinic staff member, and you will be notified of next steps.
Qualifications
New Grads will not be considered at this time, 2+ years of APP experience in Hematology or Oncology
Acute Care Nurse Practitioner: Masters-prepared graduate of an accredited school of nursing and Nurse Practitioner program. Current AZ RN and APRN license and certification as a ACNP.
Physician Assistant: Graduate of accredited Physician Assistant program with current PA certification by NCCPA and registration as a PA by the AZ State Board of Medical Practice.
Additional Qualifications:
Active BLS and ACLS certification from American Heart Association or American Red Cross at start date and DEA registration required.
Exemption Status
Exempt
Compensation Detail
Education, experience and tenure may be considered along with internal equity when job offers are extended.
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80 hours/pay period
Schedule Details
Team self schedules 12 hour schedule
Weekend Schedule
Weekends and Holidays working with 4 other team members to self schedule. Immediate Care Clinic is open 365 days a year/holidays and weekends covered. Hem C and Oncology Services inpatient all with 7 days a week coverage plan.
International Assignment
No
Site Description
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
LaTasha Perkins
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Get Access To All JobsTips for Finding OPT Sponsorship in Acute Care Nurse Practitioner
Verify your NP certification before applying
ACNPC-AG or AGACNP-BC certification is required before most acute care positions will consider you. Credentialing delays can eat into your OPT window, so sit for boards as early as possible after graduation.
Target large hospital systems over small practices
Academic medical centers and large health systems like Kaiser, Dignity Health, and HCA typically have dedicated immigration teams familiar with H-1B visa sponsorship. Smaller outpatient practices often lack the infrastructure to support visa sponsorship processes.
Confirm state licensure requirements early
NP scope of practice varies significantly by state. Some states have full practice authority; others require physician collaboration agreements. Identify states where licensing timelines align with your OPT start date to avoid authorization gaps.
Ask about H-1B sponsorship during the offer stage
Raise sponsorship intentions before accepting an offer, not after onboarding. Frame it as future planning: you are authorized now on OPT and will need H-1B filing before your authorization expires. Most large systems expect this conversation.
Use your OPT period to build specialty documentation
Document every critical care case type, procedure, and patient population you manage. This record strengthens both specialty occupation arguments for H-1B and any future O-1 visa petition if H-1B lottery selection does not occur.
Understand your STEM OPT eligibility before you graduate
Some nursing programs qualify for 24-month STEM OPT extensions; many do not. Confirm your program's CIP code with your DSO before graduation so you can plan your employer reporting requirements and 12 versus 36-month authorization timeline accurately.
Acute Care Nurse Practitioner OPT: Frequently Asked Questions
Can I work as an Acute Care Nurse Practitioner on OPT?
Yes, but your OPT authorization must be in a field directly related to your degree. If you graduated from an acute care or advanced practice nursing program, working as an Acute Care NP qualifies. You must also hold active NP certification and a valid state license before your start date. Working without these in place violates both OPT rules and state practice law.
Do hospitals commonly sponsor Acute Care NPs for H-1B visas?
Large academic medical centers and integrated health systems sponsor Acute Care NPs at meaningful rates. The specialty occupation argument is well-established for NPs because the role requires a graduate-level nursing degree and national certification. Smaller community hospitals and independent practices sponsor far less frequently, so targeting systems with existing immigration programs during your OPT period is the most practical path.
How do I find Acute Care Nurse Practitioner jobs that support OPT students?
Migrate Mate lists Acute Care NP roles specifically vetted for OPT and visa sponsorship compatibility. Filtering by sponsorship willingness saves significant time compared to applying broadly and learning mid-process that an employer does not support international candidates. Use Migrate Mate to identify employers with a documented history of sponsoring healthcare workers before investing in the application process.
Does my nursing degree qualify for STEM OPT extension?
It depends on your program's Classification of Instructional Programs code. Standard BSN and MSN programs typically do not qualify for the 24-month STEM extension. However, some nursing informatics, clinical systems, or bioinformatics-adjacent programs do qualify. Check with your Designated School Official before graduation. If you do not qualify for STEM OPT, you have 12 months of work authorization, making early H-1B planning critical.
What happens if I do not get selected in the H-1B lottery during my OPT period?
If H-1B lottery selection does not occur and your OPT authorization is expiring, you have a few options. You can explore the O-1A visa if your clinical or research record supports an extraordinary ability argument. Some Acute Care NPs also qualify for TN visa status if they are Canadian or Mexican citizens. Otherwise, returning to school for an additional degree resets your OPT eligibility and buys additional authorized time.