OPT Clinical Operations Director Jobs
Clinical Operations Director jobs are a strong fit for F-1 OPT students with backgrounds in clinical research, public health, or biomedical sciences. Most roles qualify as specialty occupations, supporting H-1B visa sponsorship after OPT. Your 12-month standard OPT window applies, with a 24-month STEM extension available if your degree qualifies.
Find OPT Clinical Operations Director JobsOverview
Showing 5 of 986+ Clinical Operations Director jobs
See all 986+ Clinical Operations Director Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Clinical Operations Director roles.
Get Access To All JobsINTRODUCTION
The AI & ML Operations Engineer designs, builds, and maintains the engineering processes and platform capabilities needed to deploy, monitor, govern, and maintain deployed AI/ML solutions at scale. The role converts validated analytical work into reliable production solutions and manages the operational lifecycle of models and related services while meeting enterprise privacy, security, and support standards.
The engineer partners with data scientists, data engineers, central cloud and infrastructure teams, API and Interoperability teams, Cybersecurity, service owners, and relevant engineering teams to deliver maintainable solutions. The role remains hands-on in engineering, testing, deployment, and troubleshooting while using enterprise-managed capabilities for production data movement, integration, and infrastructure. Scientific method validation remains with the Data Scientist and designated reviewers; this position implements the operational controls for deployed solutions.
This role is part of a new AI & Automation engineering team and will directly design, build, deploy, and support production AI applications and services. Work may include agents, retrieval-augmented generation, orchestration, APIs and integrations, automated evaluation and testing frameworks, observability, monitoring, release and rollback processes, and model/application lifecycle management.
Responsibilities
Model deployment and orchestration. Deploy batch and real-time models and related AI services using approved CI/CD, containers, APIs, and workflow patterns. Build and maintain assigned model deployment and runtime components and coordinate dependencies with enterprise platform owners.
Release management. Automate packaging, versioning, testing, promotion, rollback, and recovery for models and services. Implement retraining or recalibration workflows using criteria defined with data scientists and the required validation and release approvals.
ML platform capabilities. Implement, integrate, configure, and operate approved feature stores, model registries, experiment tracking, and related ML lifecycle capabilities with enterprise platform owners. Partner with Cloud & AI Deployment Engineering and central cloud teams on compute, storage, networking, and deployment.
Deployed-model governance. Implement approved lifecycle controls, access restrictions, lineage, audit trails, change records, and release approvals for deployed models. Maintain traceability across data, code, model, and configuration versions.
Monitoring and reliability. Implement logging, alerts, and monitoring for model performance, drift, data quality, latency, availability, and errors. Work with data scientists, service owners, and relevant engineering teams on measures, thresholds, incident response, and service objectives.
Data and API integration. Work with central data-engineering teams on managed data pipelines and with enterprise API and Interoperability teams on real-time and application integrations, including MuleSoft or other approved API capabilities. Coordinate monitoring, recovery checkpoints, restart procedures, security, and support ownership.
Enterprise support and maintainability. Ensure production solutions have documented dependencies, operational procedures, escalation paths, and ongoing ownership before release. Arrange support with the responsible enterprise teams, including 24/7 coverage where required for critical services, rather than relying on an individual project owner.
AI application operations. Operate assigned LLM, retrieval-based, and agent applications using automated quality checks, model/tool tracing, prompt and configuration versioning, and usage/cost monitoring within the common production lifecycle.
Security and engineering standards. Apply enterprise privacy, security, encryption, role-based access, and sensitive-data controls. Follow common infrastructure-as-code, pull-request, and deployment practices with the responsible teams; bring needed tooling or design exceptions through established review processes.
Collaboration and improvement. Help scientists and partner teams move prototypes into supported production solutions. Review code, tests, and documentation, resolve incidents across dependencies, provide constructive technical feedback, and improve reliability, reproducibility, performance, and efficiency.
BASIC QUALIFICATIONS
- B.S./B.A. in Computer Science, Engineering, Information Systems, or a related field, or an equivalent combination of education and relevant experience.
- At least three years of experience in software engineering, DevOps, or MLOps, including work with production systems.
- Proficiency in Python or another modern programming language, such as Java or Go, sufficient to build, test, troubleshoot, and maintain production components.
- Hands-on experience deploying and operating batch and/or real-time machine-learning models in production.
- Experience with CI/CD tools such as GitHub Actions, GitLab CI, Jenkins, or Azure DevOps; source control, code review, automated testing, and controlled releases.
- Hands-on experience with containerization and orchestration technologies using enterprise-approved platforms and tools.
- Experience in cloud and/or hybrid environments such as AWS, Azure, or GCP.
- Working knowledge of SQL and experience with large datasets and data-workflow orchestration; ability to integrate model services with enterprise-managed pipelines and APIs.
- Experience implementing logging, metrics, monitoring, alerts, and operational diagnostics and investigating failures across model, application, data, and infrastructure dependencies.
- Understanding of security best practices, role-based access control, secrets management, and handling sensitive data.
- Ability to independently deliver assigned engineering work, communicate technical tradeoffs, and collaborate with data scientists, clinicians, data/API teams, cloud/DevOps, security, and support functions.
PREFERRED QUALIFICATIONS
- Experience in healthcare, health technology, or another regulated industry handling PHI/PII.
- Familiarity with EHR/EMR integration and healthcare data standards such as HL7/FHIR, ICD, CPT, LOINC, or SNOMED.
- Experience with ML lifecycle tools such as MLflow, Kubeflow, SageMaker, Vertex AI, or Azure ML, including model registries, feature stores, and experiment tracking.
- Experience with ETL/ELT, data warehouse or lakehouse platforms, enterprise API platforms, infrastructure as code, and formal production-support practices.
- Experience monitoring model drift, fairness, and explainability and implementing healthcare AI governance controls.
- Experience operating LLM, retrieval-based, or agent applications, including quality evaluation, tracing, prompt/configuration management, and cost monitoring.
COMPENSATION
- $109,449.60 - $154,523.20 Annual
INTRODUCTION
The AI & ML Operations Engineer designs, builds, and maintains the engineering processes and platform capabilities needed to deploy, monitor, govern, and maintain deployed AI/ML solutions at scale. The role converts validated analytical work into reliable production solutions and manages the operational lifecycle of models and related services while meeting enterprise privacy, security, and support standards.
The engineer partners with data scientists, data engineers, central cloud and infrastructure teams, API and Interoperability teams, Cybersecurity, service owners, and relevant engineering teams to deliver maintainable solutions. The role remains hands-on in engineering, testing, deployment, and troubleshooting while using enterprise-managed capabilities for production data movement, integration, and infrastructure. Scientific method validation remains with the Data Scientist and designated reviewers; this position implements the operational controls for deployed solutions.
This role is part of a new AI & Automation engineering team and will directly design, build, deploy, and support production AI applications and services. Work may include agents, retrieval-augmented generation, orchestration, APIs and integrations, automated evaluation and testing frameworks, observability, monitoring, release and rollback processes, and model/application lifecycle management.
Responsibilities
Model deployment and orchestration. Deploy batch and real-time models and related AI services using approved CI/CD, containers, APIs, and workflow patterns. Build and maintain assigned model deployment and runtime components and coordinate dependencies with enterprise platform owners.
Release management. Automate packaging, versioning, testing, promotion, rollback, and recovery for models and services. Implement retraining or recalibration workflows using criteria defined with data scientists and the required validation and release approvals.
ML platform capabilities. Implement, integrate, configure, and operate approved feature stores, model registries, experiment tracking, and related ML lifecycle capabilities with enterprise platform owners. Partner with Cloud & AI Deployment Engineering and central cloud teams on compute, storage, networking, and deployment.
Deployed-model governance. Implement approved lifecycle controls, access restrictions, lineage, audit trails, change records, and release approvals for deployed models. Maintain traceability across data, code, model, and configuration versions.
Monitoring and reliability. Implement logging, alerts, and monitoring for model performance, drift, data quality, latency, availability, and errors. Work with data scientists, service owners, and relevant engineering teams on measures, thresholds, incident response, and service objectives.
Data and API integration. Work with central data-engineering teams on managed data pipelines and with enterprise API and Interoperability teams on real-time and application integrations, including MuleSoft or other approved API capabilities. Coordinate monitoring, recovery checkpoints, restart procedures, security, and support ownership.
Enterprise support and maintainability. Ensure production solutions have documented dependencies, operational procedures, escalation paths, and ongoing ownership before release. Arrange support with the responsible enterprise teams, including 24/7 coverage where required for critical services, rather than relying on an individual project owner.
AI application operations. Operate assigned LLM, retrieval-based, and agent applications using automated quality checks, model/tool tracing, prompt and configuration versioning, and usage/cost monitoring within the common production lifecycle.
Security and engineering standards. Apply enterprise privacy, security, encryption, role-based access, and sensitive-data controls. Follow common infrastructure-as-code, pull-request, and deployment practices with the responsible teams; bring needed tooling or design exceptions through established review processes.
Collaboration and improvement. Help scientists and partner teams move prototypes into supported production solutions. Review code, tests, and documentation, resolve incidents across dependencies, provide constructive technical feedback, and improve reliability, reproducibility, performance, and efficiency.
BASIC QUALIFICATIONS
- B.S./B.A. in Computer Science, Engineering, Information Systems, or a related field, or an equivalent combination of education and relevant experience.
- At least three years of experience in software engineering, DevOps, or MLOps, including work with production systems.
- Proficiency in Python or another modern programming language, such as Java or Go, sufficient to build, test, troubleshoot, and maintain production components.
- Hands-on experience deploying and operating batch and/or real-time machine-learning models in production.
- Experience with CI/CD tools such as GitHub Actions, GitLab CI, Jenkins, or Azure DevOps; source control, code review, automated testing, and controlled releases.
- Hands-on experience with containerization and orchestration technologies using enterprise-approved platforms and tools.
- Experience in cloud and/or hybrid environments such as AWS, Azure, or GCP.
- Working knowledge of SQL and experience with large datasets and data-workflow orchestration; ability to integrate model services with enterprise-managed pipelines and APIs.
- Experience implementing logging, metrics, monitoring, alerts, and operational diagnostics and investigating failures across model, application, data, and infrastructure dependencies.
- Understanding of security best practices, role-based access control, secrets management, and handling sensitive data.
- Ability to independently deliver assigned engineering work, communicate technical tradeoffs, and collaborate with data scientists, clinicians, data/API teams, cloud/DevOps, security, and support functions.
PREFERRED QUALIFICATIONS
- Experience in healthcare, health technology, or another regulated industry handling PHI/PII.
- Familiarity with EHR/EMR integration and healthcare data standards such as HL7/FHIR, ICD, CPT, LOINC, or SNOMED.
- Experience with ML lifecycle tools such as MLflow, Kubeflow, SageMaker, Vertex AI, or Azure ML, including model registries, feature stores, and experiment tracking.
- Experience with ETL/ELT, data warehouse or lakehouse platforms, enterprise API platforms, infrastructure as code, and formal production-support practices.
- Experience monitoring model drift, fairness, and explainability and implementing healthcare AI governance controls.
- Experience operating LLM, retrieval-based, or agent applications, including quality evaluation, tracing, prompt/configuration management, and cost monitoring.
COMPENSATION
- $109,449.60 - $154,523.20 Annual
See all 986+ OPT Clinical Operations Director Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new OPT Clinical Operations Director Jobs.
Get Access To All JobsTips for Finding OPT Sponsorship in Clinical Operations Director
Target employers with active clinical trial pipelines
Biopharmaceutical companies, CROs, and academic medical centers with ongoing Phase II or III trials hire Clinical Operations Directors regularly and are more likely to have established H-1B visa sponsorship infrastructure and dedicated immigration support.
Frame your degree as a specialty occupation match
Clinical operations roles typically require degrees in life sciences, public health, or healthcare administration. Make your application explicit about this alignment, since USCIS scrutinizes specialty occupation status for director-level clinical roles during H-1B petitions.
Raise sponsorship early in the process
Bring up your OPT status and H-1B sponsorship need before final interviews. Director-level hiring involves HR, legal, and executive sign-off, so surfacing your authorization timeline early prevents delays or last-minute withdrawals from employers unprepared to sponsor.
Verify your degree qualifies for the STEM OPT extension
Degrees in biological sciences, epidemiology, biomedical engineering, or health informatics typically qualify for 24-month STEM OPT extensions. Confirm your CIP code with your DSO before accepting a role, as extension eligibility significantly affects your sponsorship runway.
Prioritize large employers with dedicated HR compliance teams
Companies with 500 or more employees and established compliance teams process H-1B sponsorships more reliably. Smaller startups may offer the role but lack the legal infrastructure to file on time before your OPT authorization period ends.
Use your OPT period to build measurable clinical outcomes
Quantify your impact during OPT: trial enrollment rates improved, protocol deviations reduced, or site activation timelines shortened. Concrete operational metrics strengthen both your H-1B specialty occupation case and your negotiating position with sponsoring employers.
Clinical Operations Director OPT: Frequently Asked Questions
Can F-1 OPT students work as Clinical Operations Directors?
Yes. Clinical Operations Director roles qualify as specialty occupations under USCIS standards because they require a bachelor's degree or higher in a specific field such as life sciences, clinical research, or healthcare administration. Your F-1 OPT work authorization covers full-time employment in this role, provided the position matches the field on your EAD.
Do Clinical Operations Director roles typically lead to H-1B sponsorship?
Most do. Biopharmaceutical companies, contract research organizations, and hospital systems sponsoring Clinical Operations Directors have strong precedent for H-1B petitions, as the role consistently meets specialty occupation criteria. Employers in regulated clinical environments are accustomed to immigration compliance, making sponsorship more straightforward than in less regulated industries.
Where can I find Clinical Operations Director jobs that sponsor OPT students?
Migrate Mate is built specifically for F-1 OPT and visa-sponsored job seekers. You can browse Clinical Operations Director roles filtered by sponsorship availability, so you're not wasting time applying to employers who won't support your work authorization. This is more efficient than searching general job boards and filtering manually.
Does my degree qualify me for the 24-month STEM OPT extension in this field?
It depends on your specific CIP code. Degrees in biological sciences, epidemiology, biomedical engineering, health informatics, and related STEM-designated fields typically qualify. Clinical research degrees or MPH programs may qualify depending on how your institution filed the program classification. Confirm your CIP code with your DSO before your 12-month OPT window expires.
What happens if my OPT expires before my employer files an H-1B petition?
If you've applied for a STEM OPT extension before your initial OPT expires and your employer meets E-Verify requirements, you're authorized to continue working for up to 180 days while USCIS processes the extension. Director-level roles take time to fill and onboard, so confirming your employer's H-1B filing readiness before your OPT end date is critical.