OPT Quantitative Jobs
Quantitative roles in finance, data science, and research are among the most OPT-friendly positions in the U.S. job market. Employers hiring quants expect advanced degrees and technical depth, which aligns well with the STEM OPT extension, giving eligible graduates up to 36 months of work authorization to build their careers.
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Get Access To All JobsJob Title: Quantitative Clinical Pharmacology PhD Post Graduate Fellow
Job Requisition ID: 2499
Posting Start Date: 11/3/26
At Daiichi Sankyo, we are united by a single purpose, to improve lives around the world through innovative medicines. With a legacy of innovation since 1899, a presence in more than 30 countries, and more than 19,000 employees, we are advancing breakthrough therapies in oncology, cardiovascular disease, rare diseases, and immune disorders. Guided by our 2030 vision to "be an innovative global healthcare company contributing to the sustainable development of society", we are shaping a healthier, more hopeful future for patients, their families, and society.
Job Summary
Daiichi Sankyo’s PhD Fellowship Program offers early-career scientists a unique opportunity to launch their careers at the forefront of drug development and innovation focusing on advancing model informed drug development. The role will serve to establish PK/PD/efficacy/safety relationships in clinical settings to drive the development of potential drug candidates. This program is designed for recent PhD graduates and provides direct placement into a full-time role while offering structured development, mentorship, and visibility to leadership.
This particular PhD Fellowship will be within the TA Oncology department with a core focus on Quantitative Clinical Pharmacology.
Program Features:
- Direct Role Placement: Begin in a high-impact, business-critical role matched to your expertise
- Structured Development: Participate in tailored learning, professional skills workshops, and technical training
- Executive Exposure: Gain access to senior leaders and mentors across the organization
- Peer Network: Join a cohort of PhD associates for shared learning and community
- Career Acceleration: Build a long-term path within Daiichi Sankyo through strategic guidance and performance development
Responsibilities
- Perform modeling and simulation in support of clinical development of clinical candidates including non-compartmental analysis, population PK analysis and exposure-response analyses
- Work closely with study and indication leads within QCP to develop skills to serve as PK scientist/study lead towards the end of the fellowship
- Develop Model-Based Drug Development Plans (MBDD) and Clinical Pharmacology plans for early development candidates and work closely with QCP WG leads and non-clinical teams (non-clinical PK, translational science and pharmacology) to identify FIH dosing and early development plans
- Collaborate with advanced pharmacometrics, QSP and bioanalytical teams to advance skills related to Clinical Pharmacology
- Present findings and learnings to QCP leadership and other functions and externally as well
Qualifications
Ph.D. in Clinical Pharmacology, Non-Clinical Pharmacokinetics or Pharmacometrics
Experience in pharmacokinetic analysis including modeling and simulation and metabolism
Proficiency in WinNonLin, NONMEM, R and other relevant software
Strong analytical, problem-solving, and communication skills
Ability to work effectively in a collaborative, multidisciplinary environment
Travel Requirements
Ability to travel up to 10% of the time.
Salary Range:
USD$100,960.00 - USD$151,440.00
Daiichi Sankyo, Inc. is an equal opportunity/affirmative action employer. Qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.
Job Title: Quantitative Clinical Pharmacology PhD Post Graduate Fellow
Job Requisition ID: 2499
Posting Start Date: 11/3/26
At Daiichi Sankyo, we are united by a single purpose, to improve lives around the world through innovative medicines. With a legacy of innovation since 1899, a presence in more than 30 countries, and more than 19,000 employees, we are advancing breakthrough therapies in oncology, cardiovascular disease, rare diseases, and immune disorders. Guided by our 2030 vision to "be an innovative global healthcare company contributing to the sustainable development of society", we are shaping a healthier, more hopeful future for patients, their families, and society.
Job Summary
Daiichi Sankyo’s PhD Fellowship Program offers early-career scientists a unique opportunity to launch their careers at the forefront of drug development and innovation focusing on advancing model informed drug development. The role will serve to establish PK/PD/efficacy/safety relationships in clinical settings to drive the development of potential drug candidates. This program is designed for recent PhD graduates and provides direct placement into a full-time role while offering structured development, mentorship, and visibility to leadership.
This particular PhD Fellowship will be within the TA Oncology department with a core focus on Quantitative Clinical Pharmacology.
Program Features:
- Direct Role Placement: Begin in a high-impact, business-critical role matched to your expertise
- Structured Development: Participate in tailored learning, professional skills workshops, and technical training
- Executive Exposure: Gain access to senior leaders and mentors across the organization
- Peer Network: Join a cohort of PhD associates for shared learning and community
- Career Acceleration: Build a long-term path within Daiichi Sankyo through strategic guidance and performance development
Responsibilities
- Perform modeling and simulation in support of clinical development of clinical candidates including non-compartmental analysis, population PK analysis and exposure-response analyses
- Work closely with study and indication leads within QCP to develop skills to serve as PK scientist/study lead towards the end of the fellowship
- Develop Model-Based Drug Development Plans (MBDD) and Clinical Pharmacology plans for early development candidates and work closely with QCP WG leads and non-clinical teams (non-clinical PK, translational science and pharmacology) to identify FIH dosing and early development plans
- Collaborate with advanced pharmacometrics, QSP and bioanalytical teams to advance skills related to Clinical Pharmacology
- Present findings and learnings to QCP leadership and other functions and externally as well
Qualifications
Ph.D. in Clinical Pharmacology, Non-Clinical Pharmacokinetics or Pharmacometrics
Experience in pharmacokinetic analysis including modeling and simulation and metabolism
Proficiency in WinNonLin, NONMEM, R and other relevant software
Strong analytical, problem-solving, and communication skills
Ability to work effectively in a collaborative, multidisciplinary environment
Travel Requirements
Ability to travel up to 10% of the time.
Salary Range:
USD$100,960.00 - USD$151,440.00
Daiichi Sankyo, Inc. is an equal opportunity/affirmative action employer. Qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.
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Get Access To All JobsTips for Finding OPT Sponsorship in Quantitative
Confirm your degree qualifies for STEM OPT
Quantitative roles typically require degrees in mathematics, statistics, computer science, or financial engineering. If your degree is on the STEM Designated Degree Program list, you're eligible for the 24-month STEM OPT extension beyond your initial 12 months.
Target firms with a history of H-1B sponsorship
Hedge funds, quantitative trading firms, and investment banks regularly sponsor H-1B visas for quant roles. Prioritize employers with established visa sponsorship pipelines, since these firms understand the process and budget for immigration costs as standard practice.
Lead with your technical stack in applications
Employers hiring for quantitative positions evaluate Python, R, C++, and statistical modeling skills before anything else. Listing these prominently on your resume signals immediate productivity and reduces perceived risk for employers who are uncertain about sponsoring international candidates.
Apply well before your OPT start date
Quantitative hiring processes often include multiple technical interview rounds spanning four to eight weeks. Starting your job search three to four months before your authorization begins gives you enough time to complete the process without gaps in your employment eligibility.
Be transparent about your OPT timeline upfront
Quant employers value precision and straightforward communication. Stating your OPT end date and STEM extension eligibility early in the process saves time for both sides and positions you as organized rather than evasive about your work authorization situation.
Document every project with quantifiable outcomes
When competing for quant roles, specific results matter far more than general descriptions. Frame internship and research work in terms of model accuracy improvements, portfolio return contributions, or computational efficiency gains to demonstrate the impact employers expect from quantitative hires.
Quantitative OPT: Frequently Asked Questions
Can I work in a quantitative role on OPT without an employer filing anything for me?
Yes. During your standard 12-month OPT period, you can begin working as soon as USCIS approves your Employment Authorization Document (EAD). Your employer does not need to file any petition on your behalf. The STEM OPT extension requires your employer to submit a formal training plan using Form I-983, but that only applies once you seek the extension.
Which quantitative job titles are most likely to qualify for the STEM OPT extension?
Roles such as quantitative analyst, quantitative researcher, quantitative developer, risk analyst, and algorithmic trading associate typically qualify when your underlying degree is in a STEM field like mathematics, statistics, financial engineering, or computer science. The key is that both your degree and the job's primary duties must align with your STEM Designated Degree Program. Your Designated School Official can confirm eligibility before you apply.
How do I find quantitative employers who are open to sponsoring OPT students?
Browse Migrate Mate to find quantitative roles from employers who have explicitly indicated openness to OPT and visa sponsorship. Searching general job boards often buries sponsorship details in fine print. Migrate Mate filters for sponsorship-friendly employers, saving you from applying to firms that will screen you out at the offer stage simply due to work authorization.
What happens to my OPT status if a quantitative role is contract or project-based rather than full-time?
OPT allows part-time work of at least 20 hours per week and permits multiple concurrent employers, so contract and project-based arrangements can qualify. However, you must be actively engaged in work related to your degree throughout your OPT period. Gaps of 90 days or more on standard OPT, or 150 days on STEM OPT, can jeopardize your status, so contract timing matters.
Do quantitative roles at smaller firms or startups typically lead to H-1B sponsorship after OPT?
Smaller quantitative firms and fintech startups do sponsor H-1B visas, but less predictably than large banks or established hedge funds. Before accepting an offer, ask directly whether the company has sponsored H-1B petitions before, whether they work with an immigration attorney, and how they handle the lottery risk. A firm that cannot answer these questions clearly may not have the infrastructure to support your long-term status.