Pediatric Nurse Practitioner Jobs in South Carolina
Pediatric Nurse Practitioner jobs in South Carolina are open across Spartanburg, Columbia, and Denmark and other South Carolina metros, with employers like Pediatrix Medical and Family Health Centers hiring at every experience level. Find a role that fits below and apply directly.
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EXPOSURE CLASSIFICATION: Category I - All procedures or other job related tasks that involve an inherent potential for mucous membrane or skin contact with blood, body fluids, tissues, or a potential for spill or splashes of blood or body fluids.
QUALIFICATIONS: A master’s degree in nursing is required. Must possess a State of South Carolina license to practice medicine, federal DEA license and a State of South Carolina Controlled Substance license. Two years of management/supervisory experience is required. Must meet credentialing and privileging requirements of FHC.
Physical Requirements: Must possess ability to communicate in the dominant language of the geographic region. Must be able to lift 30 pounds. Vision and hearing corrected to within normal limits is required. Must be independently mobile.
Responsibilities:
- Provide direct patient care, including but not limited to conducting comprehensive medical and social histories of patients, performing comprehensive and/or problem focused physical examinations, order and/or performing laboratory and screening test in accordance with approved protocol.
- Read and evaluate lab reports, x-ray results, and consultation reports and records, relaying information and, if necessary, treatment plans to patients.
- Make independent decisions regarding management and treatment of medical problems identified, formulating, initiating and monitoring patient management plans based on established standards of care.
- Prescribe medications and perform therapeutic or corrective measures, which may include urgent care.
- Provide information, instruction and counseling on health maintenance, health promotion, social problems, illness prevention, illness management and medicine use.
- Make appropriate referrals to specialists.
- Comply with all applicable infection control and safety precautions.
- Consult with other members of the health care team as needed.
- Accurately enter all patient notes into electronic medical records system in a timely manner.
- Participate in interviewing and selecting new employees provide input for performance reviews, provide input for employee discipline, including discharge.
- Supervise students during clinical rotations as assigned.
- Exhibit compliance with FHC’s corporate compliance policy.
- Perform job activities in ways that are respectful, courteous and responsive while interacting with patients, visitors and co-workers.
- Perform other duties and assume other responsibilities as appropriate or as directed.
See All 7 Pediatric Nurse Practitioner Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
Find JobsPediatric Nurse Practitioner Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Pediatric Nurse Practitioner Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Pediatrix Medical5

- Family Health Centers2

Top Industries Hiring
- Healthcare & Medical Services7
What South Carolina Employers Look For
The qualifications that appear most often in pediatric nurse practitioner jobs across South Carolina.
- Active APRN license and national certification as a Pediatric Nurse Practitioner (CPNP-PC or CPNP-AC)
- Master of Science in Nursing (MSN) or Doctor of Nursing Practice (DNP) from an accredited program
- Current DEA registration and prescriptive authority in the state of practice
- Minimum one to three years of clinical experience in a pediatric or family practice setting
- Basic Life Support (BLS) and Pediatric Advanced Life Support (PALS) certifications
- Proficiency with electronic health record systems such as Epic, Cerner, or similar platforms
Pediatric Nurse Practitioner Jobs in South Carolina: Frequently Asked Questions
How many pediatric nurse practitioner jobs are there in South Carolina?
There are 7+ pediatric nurse practitioner openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Spartanburg, Columbia, and Denmark. New positions post regularly as employers across South Carolina hire.
How much do pediatric nurse practitioners make in South Carolina?
Pediatric nurse practitioners in South Carolina earn a median of about $123,290 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $97,080 for the lowest 10% to over $160,170 for the top 10%. Pay rises with experience, specialty, and employer.
Which South Carolina cities have the most pediatric nurse practitioner jobs?
Spartanburg, Columbia, and Denmark have the most pediatric nurse practitioner openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire pediatric nurse practitioners in South Carolina?
Employers hiring pediatric nurse practitioners in South Carolina include Pediatrix Medical and Family Health Centers, based on current listings on Migrate Mate as of June 2026.
Are there remote pediatric nurse practitioner jobs in South Carolina?
Yes. About 0% of pediatric nurse practitioner openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for pediatric nurse practitioner jobs in South Carolina?
You can apply to pediatric nurse practitioner jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 7 Pediatric Nurse Practitioner Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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